نتائج البحث

The variation landscape of CYP2D6 in a multi-ethnic Asian population.

• Authors : Maulana Y; Nalagenetics Pte Ltd, Singapore, Singapore.; Toro Jimenez R

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism ; Asian People*/Asian People*/Asian People*/genetics

• Source: Scientific reports [Sci Rep] 2024 Jul 20; Vol. 14 (1), pp. 16725. Date of Electronic Publication: 2024 Jul 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Into a Deeper Understanding of CYP2D6's Role in Risperidone Monotherapy and the Potential Side Effects in Schizophrenia Spectrum Disorders.

• Authors : Bondrescu M; Department of Neurosciences-Psychiatry, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Timis County Emergency Clinical Hospital 'Pius Brinzeu', Liviu Rebreanu 156, 300723 Timisoara, Romania.

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism ; Risperidone*/Risperidone*/Risperidone*/adverse effects

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 08; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

Rationale and design for a pragmatic randomized trial to assess gene-based prescribing for SSRIs in the treatment of depression.

• Authors : Hines LJ; IGNITE Pragmatic Trials Network

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Depression*/Depression*/Depression*/drug therapy

• Source: Clinical and translational science [Clin Transl Sci] 2024 Jun; Vol. 17 (6), pp. e13822.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

تفاصيل العنوان

Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study.

• Authors : Brouwer JMJL; Research School of Behavioral and Cognitive Neurosciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. .; GGZ Drenthe Mental Health Center Drenthe, Assen, The Netherlands. .

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/therapeutic use

• Source: BMC psychiatry [BMC Psychiatry] 2024 May 27; Vol. 24 (1), pp. 394. Date of Electronic Publication: 2024 May 27.Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X

تفاصيل العنوان

Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea.

• Authors : Huh KY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, Seoul, South Korea.; Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul, South Korea.

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Pharmacogenetics*; Female

• Source: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13772.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

تفاصيل العنوان

Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine.

• Authors : Smith, Robert Løvsletten^1,2 (AUTHOR); Wollmann, Birgit M.¹ (AUTHOR); Størset, Elisabet¹ (AUTHOR)

• Source: CTS: Clinical & Translational Science. Feb2024, Vol. 17 Issue 2, p1-7. 7p.

تفاصيل العنوان

A consideration of CYP2D6 genetic variations in the Ghanaian population as a potential 'culprit' for the tramadol 'abuse crisis'.

• Authors : Thomford, Nicholas Ekow^1,2,3 (AUTHOR) ; Abraham, Susanna Aba⁴ (AUTHOR); Nyarko, Samuel Badu^1,2 (AUTHOR)

• Source: BMC Medical Genomics. 1/22/2024, Vol. 17 Issue 1, p1-6. 6p.

تفاصيل العنوان

Impact of CYP2D6 and CYP2B6 phenotypes on the response to tramadol in patients with acute post‐surgical pain.

• Authors : Casajús, Ana¹ (AUTHOR); Zubiaur, Pablo¹ (AUTHOR) ; Alday, Enrique² (AUTHOR)

• Source: CTS: Clinical & Translational Science. Jan2024, Vol. 17 Issue 1, p1-14. 14p.

تفاصيل العنوان

No drug-drug interactions between selective prolyl-tRNA synthetase inhibitor, bersiporocin, and pirfenidone or nintedanib in healthy participants.

• Authors : Shin W; Department of Clinical Pharmacology and Therapeutics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea.; CHA Global Clinical Trial Center, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.

Subjects: Cytochrome P-450 CYP2D6* ; Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/chemically induced ; Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/drug therapy

• Source: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13701.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

تفاصيل العنوان

N, N -dimethyltryptamine forms oxygenated metabolites via CYP2D6 - an in vitro investigation.

• Authors : Eckernäs E; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Macan-Schönleben A

Subjects: Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism ; N,N-Dimethyltryptamine*/N,N-Dimethyltryptamine*/N,N-Dimethyltryptamine*/metabolism; Humans

• Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2023 Dec; Vol. 53 (8-9), pp. 515-522. Date of Electronic Publication: 2023 Nov 26.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان