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A Novel Platform Featuring Nanomagnetic Ligand Fishing Based on Fixed-Orientation Immobilized Magnetic Beads for Screening Potential Cyclooxygenase-2 Inhibitors from Panax notoginseng Leaves.

• Authors : Zhang F; College of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.; Sun F

Subjects: Plant Leaves*/Plant Leaves*/Plant Leaves*/chemistry ; Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/chemistry ; Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/pharmacology

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 09; Vol. 29 (23). Date of Electronic Publication: 2024 Dec 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Two-Step Cell Death Induction by the New 2-Arachidonoyl Glycerol Analog and Its Modulation by Lysophosphatidylinositol in Human Breast Cancer Cells.

• Authors : Akimov, Mikhail G.¹ (AUTHOR) ; Gretskaya, Natalia M.¹ (AUTHOR) ; Gorbacheva, Evgenia I.¹ (AUTHOR)

Subjects: *TRPV cation channels; *CYCLOOXYGENASE 2 inhibitors; *ANTIOXIDANT analysis

• Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p820. 17p.

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Discovery of new thymol-3,4-disubstituted thiazole hybrids as dual COX-2/5-LOX inhibitors with in vivo proof.

• Authors : El-Miligy MMM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Al-Kubeisi AK

Subjects: Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/pharmacology ; Thymol*/Thymol*/Thymol*/pharmacology; Rats

• Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2024 Dec; Vol. 39 (1), pp. 2309171. Date of Electronic Publication: 2024 Jan 30.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Pyrimidine Derivatives as Selective COX-2 Inhibitors with Anti-Inflammatory and Antioxidant Properties.

• Authors : Tylińska B; Department of Organic Chemistry, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.; Janicka-Kłos A

Subjects: Pyrimidines*/Pyrimidines*/Pyrimidines*/pharmacology ; Pyrimidines*/Pyrimidines*/Pyrimidines*/chemistry ; Antioxidants*/Antioxidants*/Antioxidants*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 13; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Immunohistochemical Investigation of Cyclooxygenase-2 Expression in Rabbit Uterine Adenocarcinoma and the Potential Use of COX-2 Inhibitors in Cancer Therapy.

• Authors : Vaccaro, Emanuela¹ (AUTHOR) ; Navas, Luigi¹ (AUTHOR) ; Ercolano, Martina¹ (AUTHOR)

• Source: Animals (2076-2615). Nov2024, Vol. 14 Issue 22, p3169. 14p.

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Development of Novel Gel Formulation of Celecoxib and Bio-active Compounds of Herbs for Pain Management.

• Authors : Mudgade, Satish Channappa¹; Dharashivkar, Sanket¹; Malviya, Rajeev¹

• Source: International Journal of Pharmacy & Life Sciences. Nov2024, Vol. 15 Issue 11, p4-8. 5p.

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Synergistic Effect of Caloric Restriction and Cyclooxygenase-2 Inhibitor "Celecoxib" Against IGFs/COX-2 Mediating Chemically Induced Hepatocellular Carcinoma in Rats.

• Authors : ShamsEldeen, Asmaa Mohammed¹; El Hamzawy, Magda¹; Aboulhoda, Basma Emad²

• Source: International Journal of Morphology. 2024, Vol. 42 Issue 6, p1628-1637. 10p.

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Virtual screening of Ginsenosides for COX-2 inhibition: Insights from in silico docking studies.

• Authors : Khare, Chitransh¹; Jain, Swati¹; Prajapati, Harshal¹

• Source: Indian Journal of Biochemistry & Biophysics. Oct2024, Vol. 61 Issue 10, p581-588. 8p.

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Development, Characterization, and Cellular Toxicity Evaluation of Solid Dispersion-Loaded Hydrogel Based on Indomethacin.

• Authors : Dahma, Zaid¹ (AUTHOR) ; Ibáñez-Escribano, Alexandra² (AUTHOR) ; Fonseca-Berzal, Cristina² (AUTHOR)

Subjects: *CYCLOOXYGENASE 2 inhibitors; *DRUG solubility; *X-ray powder diffraction

• Source: Polymers (20734360). Aug2024, Vol. 16 Issue 15, p2174. 18p.

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Modification and Characterization of Some New Levofloxacin Heterocyclic Derivatives as COX-2 Enzyme Inhibitors and Evaluate Their Efficacy Pharmacokinetics by Molecular Docking and the Swiss ADME Studies.

• Authors : Rabeaa, Mustafa Moaied¹; Khalaf, Muna Ismael¹

Subjects: *CYCLOOXYGENASE 2 inhibitors; *MOLECULAR docking; *ENZYME inhibitors

• Source: Baghdad Science Journal. 2024, Vol. 21 Issue 4, p1255-1274. 20p.

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