نتائج البحث

Cyclin Dependent Kinase 2 (CDK2) Inhibitors in Oncology Clinical Trials: A Review.

• Authors : House, Isabelle¹; Valore-Caplan, Mari¹; Maris, Elijah¹

• Source: Journal of Immunotherapy & Precision Oncology. Feb2025, Vol. 8 Issue 1, p47-54. 8p.

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Clinicopathological Significance of Cyclin-Dependent Kinase 2 (CDK2) in Ductal Carcinoma In Situ and Early-Stage Invasive Breast Cancers.

• Authors : Lashen A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Nottingham University Hospital, City Campus, Nottingham NG5 1PB, UK.

Subjects: Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/metabolism ; Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 06; Vol. 25 (9). Date of Electronic Publication: 2024 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Design, Molecular Docking, Synthesis, Characterization and Preliminary Evaluation of Novel 1,3,4-Oxadiazole Derivatives as Cyclin-Dependent Kinase 2 Inhibitors

• Authors : Yousef Sabah Ali; Monther Faisal Mahdi; Basma Monjid Abd Razik

Subjects: 1,3,4-Oxadiazole; Colon Cancer; Molecular Docking

• Source: Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 25, Iss 1 (2025)

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COMPOUNDS FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEOSOME PATHWAY

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Synthesis, docking, MD simulation, ADMET, drug likeness, and DFT studies of novel furo[2,3-b]indol-3a-ol as promising Cyclin-dependent kinase 2 inhibitors.

• Authors : Gheidari D; Department of Chemistry, Faculty of Science, University of Guilan, Rasht, Iran. .; Mehrdad M

Subjects: Molecular Dynamics Simulation* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Molecular Docking Simulation

• Source: Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3084. Date of Electronic Publication: 2024 Feb 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma

• Authors : Sonntag, Roland; Giebeler, Nives; Nevzorova, Yulia

Subjects: 577.2; Ciencias Biomédicas; Biología

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Inhibition of Cyclin-dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury

• Authors : Xu, Jin; Xue, Zhengze; Zhang, Cheng

Subjects: Biomedical and Clinical Sciences; Clinical Sciences; Immunology

• Source: Transplantation, vol Publish Ahead of Print, iss &NA

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Anticancer effects of pomegranate-derived peptide PG2 on CDK2 and miRNA-339-5p-mediated apoptosis via extracellular vesicles in acute leukemia.

• Authors : Charoensedtasin K; Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, 999 Phuttamonthon sai 4 Road, Salaya, Phuttamonthon, Nakhon Pathom, 73170, Thailand.; Norkaew C

Subjects: Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/drug effects ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

• Source: Scientific reports [Sci Rep] 2024 Nov 09; Vol. 14 (1), pp. 27367. Date of Electronic Publication: 2024 Nov 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Inertial effect of cell state velocity on the quiescence-proliferation fate decision.

• Authors : Venkatachalapathy H; Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, USA.; Brzakala C

Subjects: Cell Proliferation*/Cell Proliferation*/Cell Proliferation*/physiology ; Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/metabolism ; Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/Cyclin-Dependent Kinase 2*/genetics

• Source: NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Oct 02; Vol. 10 (1), pp. 111. Date of Electronic Publication: 2024 Oct 02.Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model:

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LaCl3⋅7H2O as an Effective Catalyst for the Synthesis of α-Aminophosphonates under Solvent-Free Conditions and Docking Simulation of Ligand Bond Complexes of Cyclin-Dependent Kinase 2.

• Authors : Mirzaei, Mahdi¹ (AUTHOR); Eshghi, Hossein¹ (AUTHOR); Sabbaghzadeh, Reihaneh² (AUTHOR)

Subjects: *CATALYST synthesis; *MOLECULAR docking; *SYNTHETIC proteins

• Source: Polycyclic Aromatic Compounds. 2022, Vol. 42 Issue 9, p5882-5892. 11p.

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