نتائج البحث

Regulation and Pharmacology of the Cyclic GMP and Nitric Oxide Pathway in Embryonic and Adult Stem Cells.

• Authors : Kots AY; Veteran Affairs Palo Alto Health Care System, US Department of Veteran Affairs, Palo Alto, CA 90304, USA.; Bian K

Subjects: Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/cytology ; Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/drug effects ; Adult Stem Cells*/Adult Stem Cells*/Adult Stem Cells*/metabolism

• Source: Cells [Cells] 2024 Dec 05; Vol. 13 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

تفاصيل العنوان

Auto/Paracrine C-Type Natriuretic Peptide/Cyclic GMP Signaling Prevents Endothelial Dysfunction.

• Authors : Werner F; Institute of Physiology, University Würzburg, 97070 Würzburg, Germany.; Naruke T

Subjects: Natriuretic Peptide, C-Type*/Natriuretic Peptide, C-Type*/Natriuretic Peptide, C-Type*/metabolism ; Natriuretic Peptide, C-Type*/Natriuretic Peptide, C-Type*/Natriuretic Peptide, C-Type*/genetics ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 16; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

Vericiguat prevents high glucose-mediated impaired vascular smooth muscle cGMP production and vasorelaxation.

• Authors : Polhemus D; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Almodiel D

Subjects: Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/metabolism ; Cyclic GMP*/Cyclic GMP*/Cyclic GMP*/biosynthesis ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/drug effects

• Source: Scientific reports [Sci Rep] 2025 Feb 10; Vol. 15 (1), pp. 4939. Date of Electronic Publication: 2025 Feb 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway.

• Authors : Zhang K; College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.; Xu Y

Subjects: Colitis*/Colitis*/Colitis*/metabolism ; Colitis*/Colitis*/Colitis*/drug therapy ; Bile Acids and Salts*/Bile Acids and Salts*/Bile Acids and Salts*/metabolism

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (43), pp. e2406917. Date of Electronic Publication: 2024 Sep 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

تفاصيل العنوان

Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP

• Authors : Yang, JN; Sundqvist, ML; Zheng, XW

Subjects: Medicin och hälsovetenskap

• Source: The Journal of clinical investigation. 133(17)

تفاصيل العنوان

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING) (ROXANE)

• Source: Pro-inflammatory Role of Extracellular DNA in Inflammatory Bowel Disease in Children: Study of the cGAS-STING PathwayAhn J, Son S, Oliveira SC, Barber GN. STING-Dependent Signaling Underlies

تفاصيل العنوان

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells

• Authors : Preethi Jayakumar; Ting Jiang; Hai Huang

Subjects: class A ODN; TLR9 agonist; CGAS

• Source: Frontiers in Pharmacology, Vol 16 (2025)

تفاصيل العنوان

ENGINEERED CYCLIC GMP-AMP SYNTHASE (cGAS) VARIANT ENZYMES

تفاصيل العنوان

Brain endothelial cyclic GMP-AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling pathway in aging and neurodegeneration

• Authors : Bryan Sun; Lulin Li; Jian Luo

Subjects: Neurology. Diseases of the nervous system; RC346-429

• Source: Neural Regeneration Research, Vol 20, Iss 7, Pp 2005-2007 (2025)

تفاصيل العنوان

Chronic circadian rhythm disorder induces heart failure with preserved ejection fraction-like phenotype through the Clock-sGC-cGMP-PKG1 signaling pathway.

• Authors : Che Y; Department of Cardiology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, 466-8550, Japan.; Shimizu Y

Subjects: Chronobiology Disorders*/Chronobiology Disorders*/Chronobiology Disorders*/complications ; Chronobiology Disorders*/Chronobiology Disorders*/Chronobiology Disorders*/metabolism ; CLOCK Proteins*/CLOCK Proteins*/CLOCK Proteins*/metabolism

• Source: Scientific reports [Sci Rep] 2024 May 11; Vol. 14 (1), pp. 10777. Date of Electronic Publication: 2024 May 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان