نتائج البحث

Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells. ...

• Authors : Barbieri, Laura; Veliça, Pedro; Gameiro, Paulo A

Subjects: CD8+ T cells; lactate; metabolism

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The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome.

• Authors : Foskolou, Iosifina P; Barbieri, Laura; Vernet, Aude

Subjects: Animals; CD8-Positive T-Lymphocytes; Glutarates

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Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses. ...

• Authors : Bargiela, David; Cunha, Pedro P; Veliça, Pedro

Subjects: CD8+ lymphocytes; hypoxia; immunotherapy

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Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation. ...

• Authors : Gojkovic, Milos; Cunha, Pedro P; Darmasaputra, Gabriella S

Subjects: HIF; Nitric oxide; Prolyl hydroxylase inhibitors

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The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome. ...

• Authors : Foskolou, Iosifina P; Barbieri, Laura; Vernet, Aude

Subjects: Animals; CD8-Positive T-Lymphocytes; Glutarates

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Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy

• Authors : Pedro P. Cunha; Eleanor Minogue; Lena C. M. Krause ...

Subjects: CAR-T cell therapy; lymphocyte subsets; General Immunology and Microbiology

• Source: eLife. 12

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Infiltration of Tumors Is Regulated by T cell-Intrinsic Nitric Oxide Synthesis

• Authors : Pedro P. Cunha; David Bargiela; Eleanor Minogue ...

Subjects: Mice, Knockout; Cancer Research; Mice

• Source: Cunha, P P, Bargiela, D, Minogue, E, Krause, L C M, Barbieri, L, Brombach, C, Gojkovic, M, Marklund, E, Pietsch, S, Foskolou, I, Branco, C M, Veliça, P & Johnson, R S

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