نتائج البحث

Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

• Authors : Díaz, Roberto Efraín; Ecker, Andrew K; Correy, Galen J

Subjects: Biochemistry and Cell Biology; Biological Sciences; Underpinning research

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Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2

• Authors : Gahbauer, Stefan; Correy, Galen J; Schuller, Marion

Subjects: Theory Of Computation; Biochemistry and Cell Biology; Biological Sciences

• Source: Proceedings of the National Academy of Sciences of the United States of America. 120(2)

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A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

• Authors : Taha, Taha Y; Suryawanshi, Rahul K; Chen, Irene P

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Biological Sciences

• Source: PLOS Pathogens. 19(8)

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Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data

• Authors : Weiss, Manfred S; Wollenhaupt, Jan; Correy, Galen J

Subjects: Medicinal and Biomolecular Chemistry; Chemical Sciences; Crystallography

• Source: Protein Science. 31(9)

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The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

• Authors : Correy, Galen J; Kneller, Daniel W; Phillips, Gwyndalyn

Subjects: Inorganic Chemistry; Biochemistry and Cell Biology; Chemical Sciences

• Source: Science Advances. 8(21)

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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

• Authors : Schuller, Marion; Correy, Galen J; Gahbauer, Stefan

Subjects: Theory Of Computation; Biochemistry and Cell Biology; Biological Sciences

• Source: Science Advances. 7(16)

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Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

• Authors : Schuller, Marion; Correy, Galen J; Gahbauer, Stefan

Subjects: Theory Of Computation; Biochemistry and Cell Biology; Biological Sciences

• Source: bioRxiv. 1(12-02)

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Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data

• Authors : Weiss, Manfred S.; Wollenhaupt, Jan; Correy, Galen J.

Subjects: compositional heterogeneity; conformational heterogeneity; fragment-screening

• Source: Weiss , M S , Wollenhaupt , J , Correy , G J , Fraser , J S , Heine , A ,

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Author response: Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

• Authors : Díaz, Roberto Efraín; Ecker, Andrew K; Correy, Galen J ...

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Overcoming insecticide resistance through computational inhibitor design

• Authors : Correy, Galen J.; Zaidman, Daniel; Harmelin, Alon

• Source: Correy , G J , Zaidman , D , Harmelin , A , Carvalho , S , Mabbitt , P D , Calaora , V , James , P J ,

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