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Organoids as a biomarker for personalized treatment in metastatic colorectal cancer:drug screen optimization and correlation with patient response

• Authors : Smabers, Lidwien P; Wensink, Emerens; Verissimo, Carla S

Subjects: Cancer; Chemotherapy; Colorectal cancer

• Source: Smabers , L P , Wensink , E , Verissimo , C S , Koedoot , E , Pitsa , K-C , Huismans , M A , Higuera Barón , C , Doorn , M , Valkenburg-van Iersel , L B , Cirkel , G A , Brousali , A , Overmeer , R ,

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Safety and effectiveness of aflibercept in combination with FOLFIRI in Korean patients with metastatic colorectal cancer who received oxaliplatin-containing regimen

• Authors : Seung-Hoon Beom; Jong Gwang Kim; Seung Hyuk Baik

Subjects: Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Bevacizumab / therapeutic use; Camptothecin / therapeutic use

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Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal model

• Authors : Wintjens, Anne G.W.E.; Liu, Hong; Fransen, Peter Paul K.H.

Subjects: Colorectal cancer; Injectable supramolecular hydrogel; Intraperitoneal delivery

• Source: Wintjens , A G W E , Liu , H , Fransen , P P K H , Lenaerts , K , van Almen , G C , Gijbels , M J , Hadfoune , M , Boonen , B T C , Lieuwes , N G , Biemans , R , Dubois , L J , Dankers , P Y W , de

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Trifluridine–tipiracil plus bevacizumab versus capecitabine plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer ineligible for intensive therapy (SOLSTICE):a randomised, open-label phase 3 study

• Authors : André, Thierry; Falcone, Alfredo; Shparyk, Yaroslav

Subjects: Antineoplastic Combined Chemotherapy Protocols/adverse effects; Bevacizumab/therapeutic use; Capecitabine/adverse effects

• Source: André , T , Falcone , A , Shparyk , Y , Moiseenko , F , Polo-Marques , E , Csöszi , T , Campos-Bragagnoli , A , Liposits , G , Chmielowska , E , Aubel , P , Martín , L , Fougeray , R , Amellal , N

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Precision medicine applied to metastatic colorectal cancer using tumor-derived organoids and in-vitro sensitivity testing:a phase 2, single-center, open-label, and non-comparative study

• Authors : Jensen, Lars Henrik; Rogatto, Silvia Regina; Lindebjerg, Jan

Subjects: Humans; Colorectal Neoplasms/pathology; Precision Medicine

• Source: Jensen , L H , Rogatto , S R , Lindebjerg , J , Havelund , B , Abildgaard , C , do Canto , L M , Vagn-Hansen , C , Dam , C , Rafaelsen , S & Hansen , T F 2023 , ' Precision medicine applied to

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Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer

• Authors : Yoshino, Takayuki; Andre, Thierry; Kim, Tae Won

Subjects: Asia; colorectal cancer; microsatellite instability

• Source: Yoshino , T , Andre , T , Kim , T W , Yong , W P , Shiu , K K , Jensen , B V , Jensen , L H , Punt , C J A , Smith , D , Garcia-Carbonero , R , Alcaide-Garcia , J , Gibbs , P , de la Fouchardiere , C

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Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

• Authors : Mertens, Sander; Huismans, Maarten A; Verissimo, Carla S

Subjects: Humans; Proto-Oncogene Proteins p21(ras)/metabolism; Colorectal Neoplasms/drug therapy

• Source: Mertens , S , Huismans , M A , Verissimo , C S , Ponsioen , B , Overmeer , R , Proost , N , van Tellingen , O , van de Ven , M , Begthel , H , Boj , S F , Clevers , H , Roodhart , J M L , Bos , J L &

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Oxaliplatin (3 months v 6 months) With 6 Months of Fluoropyrimidine as Adjuvant Therapy in Patients With Stage II/III Colon Cancer: KCSG CO09-07

• Authors : Seung Tae Kim; Sun Young Kim; Jeeyun Lee

Subjects: Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Capecitabine / therapeutic use; Chemotherapy

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Metastasis-Directed Radiotherapy for Oligoprogressive or Oligopersistent Metastatic Colorectal Cancer

• Authors : Jeongshim Lee; Woong Sub Koom; Hwa Kyung Byun

Subjects: Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Camptothecin; Colonic Neoplasms* / drug therapy

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Translation of IDEA trial results into clinical practice: Analysis of the implementation of a new guideline for colon cancer

• Authors : van Rooijen, Karlijn L.; Derksen, Jeroen W.G.; Verkooijen, Helena M. ...

Subjects: adjuvant chemotherapy; cancer registry; colon cancer

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