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A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B (BEYOND-9)

• Authors : Intellia Therapeutics

• Source: A Two-Part Open-Label Study of REGV131-LNP1265, A CRISPR/Cas9 Based Coagulation Factor IX Gene Insertion Therapy in Participants With Hemophilia B

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A Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated Children Aged 7 to Less Than 12 Years With Severe Hemophilia A, a Genetic Bleeding Disorder That is Caused by the Lack of a Protein Called Clotting Factor 8 (FVIII) in the Blood (Alfa-PROTECT)

• Source: A Phase 3, Single Group Treatment, Open-label, Study to Evaluate the Safety of BAY 94-9027 Infusions for Prophylaxis and Treatment of Bleeding in Previously Treated Children Aged 7 to

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A single-center study of patients with rare isolated acquired clotting factor deficiencies other than acquired hemophilia A

• Authors : Dandan Yu; Feng Xue; Xiaofan Liu

Subjects: acquired clotting factor deficiency; bleeding; diagnosis

• Source: Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 6, Pp 102554- (2024)

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Real-World Amount of Clotting Factor Products and Non-Factor Products Dispensed and Annual Medical Expenditures for Japanese Patients with Haemophilia A

• Authors : Masato Bingo; Katsuyuki Fukutake; Kanae Togo

Subjects: Therapeutics. Pharmacology; RM1-950; Pharmacy and materia medica

• Source: Drugs - Real World Outcomes, Vol 11, Iss 3, Pp 541-552 (2024)

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Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia : A review of the literature

• Authors : Iorio, Alfonso; Königs, Christoph; Reding, Mark T.

Subjects: arthropathy; bleeding; episodic/on-demand treatment

• Source: Haemophilia. 29(1):33-44

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Discovery of Heparin Mimetic, Potent, and Selective Inhibitors of Human Clotting Factor XIIIa

• Authors : Kayla T. Vu; Srabani Kar; Navneet Goyal

Subjects: Chemistry; QD1-999

• Source: ACS Omega, Vol 9, Iss 28, Pp 31105-31119 (2024)

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Mathematical modeling identifies clotting factor combinations that modify thrombin generation in normal and factor VIII-, IX-, or XI-deficient blood

• Authors : Michael T. Stobb; Keith B. Neeves; Dougald M. Monroe

Subjects: factor V; hemophilia; hemostasis

• Source: Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102570- (2024)

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Clotting Factor Deficiencies as an Underlying Cause of Abnormal Uterine Bleeding in Women of Reproductive Age: A Literature Review.

• Authors : Livanou, Maria Effrosyni¹ (AUTHOR); Matsas, Alkis¹ (AUTHOR); Valsami, Serena² (AUTHOR)

• Source: Life (2075-1729). Jun2023, Vol. 13 Issue 6, p1321. 14p.

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Optimized human clotting factor VIII gene expression cassettes and their use

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Lower Risk of Thrombosis in Blood Group O Patients: Are low clotting factor levels the reason?

• Authors : Rahila Razzak; Sana Ansari; Syed Tousif Ahmed

Subjects: Biochemistry; QD415-436; Dentistry

• Source: Pakistan Journal of Medicine and Dentistry, Vol 3, Iss 4 (2024)

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