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  • 1-10 ل  1,501 نتائج ل ""Class I Phosphatidylinositol 3-Kinases""

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Academic Journal

In Silico Discovery of a Novel PI3Kδ Inhibitor Incorporating 3,5,7-Trihydroxychroman-4-one Targeting Diffuse Large B-Cell Lymphoma.

  • Authors : Jia W; College of Chemistry and Chemical Engineering, Qilu Normal University, Jinan 250200, China.; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.

Subjects: Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/drug therapy ; Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/metabolism ; Molecular Docking Simulation*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 19; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD.

Subjects: Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/drug therapy ; Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/diagnosis ; Cross-Over Studies*

  • Source: Respiratory research [Respir Res] 2024 Oct 19; Vol. 25 (1), pp. 380. Date of Electronic Publication: 2024 Oct 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Defining the transcriptome of PIK3CA-altered cells in a human capillary malformation using single cell long-read sequencing.

  • Authors : Wedemeyer MA; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Single-Cell Analysis*/Single-Cell Analysis*/Single-Cell Analysis*/methods ; Transcriptome* Megalencephaly cutis marmorata telangiectatica congenita; Capillary Malformations, Congenital, 1

  • Source: Scientific reports [Sci Rep] 2024 Oct 25; Vol. 14 (1), pp. 25440. Date of Electronic Publication: 2024 Oct 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pulmonary artery mass with PIK3CA mutation after orthotopic heart transplantation.

  • Authors : Son AY; Division of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Northwestern Medicine, 676 N St Clair Street Suite 730, Chicago, IL, 60611-2968, USA. .; Clark AJ

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Heart Transplantation*/Heart Transplantation*/Heart Transplantation*/adverse effects ; Mutation*

  • Source: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Oct 01; Vol. 19 (1), pp. 558. Date of Electronic Publication: 2024 Oct 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090

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Academic Journal

PIK3CA mutational status in tissue and plasma as a prognostic biomarker in HR+/HER2- breast cancer.

  • Authors : Terán E; Medical Oncology Department, University Hospital of Salamanca, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy

  • Source: Cancer medicine [Cancer Med] 2024 Sep; Vol. 13 (17), pp. e70101.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Development of an in vivo syngeneic mouse transplant model of invasive intestinal adenocarcinoma driven by endogenous expression of Pik3caH1047R and Apc loss.

  • Authors : de Las Heras F; Department of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/metabolism ; Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/genetics

  • Source: PloS one [PLoS One] 2024 Aug 02; Vol. 19 (8), pp. e0308051. Date of Electronic Publication: 2024 Aug 02 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay.

  • Authors : Thao DT; Center for Genetic Consultation and Cancer Screening, 108 Military Center Hospital, Hai Ba Trung, Hanoi, Vietnam.; University of Science and Technology of Hanoi, Cau Giay, Hanoi, Vietnam.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/blood

  • Source: PloS one [PLoS One] 2024 Aug 28; Vol. 19 (8), pp. e0309209. Date of Electronic Publication: 2024 Aug 28 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Characterizing multi-PIK3CA mutations across cancer types: Toward precision oncology.

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Mutation* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: Cancer medicine [Cancer Med] 2024 Jul; Vol. 13 (14), pp. e70052.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

EGFR and PI3K Signalling Pathways as Promising Targets on Circulating Tumour Cells from Patients with Metastatic Gastric Adenocarcinoma.

  • Authors : Piper AK; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.; Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/drug therapy ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 20; Vol. 25 (10). Date of Electronic Publication: 2024 May 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

PIK3CA mutations in endocrine-resistant breast cancer.

  • Authors : Schagerholm C; Department of Oncology-Pathology, Karolinska Institutet, Bioclinicum, Stockholm, Sweden. .; Robertson S

Subjects: Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/Class I Phosphatidylinositol 3-Kinases*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2024 May 31; Vol. 14 (1), pp. 12542. Date of Electronic Publication: 2024 May 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  1,501 نتائج ل ""Class I Phosphatidylinositol 3-Kinases""