نتائج البحث

Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives

• Authors : Minjae J. Kim; Mohamed M. Ibrahim; Monica M. Jablonski

Subjects: glaucoma; parasympathetic nervous system; systems genetics

• Source: Frontiers in Molecular Biosciences, Vol 11 (2024)

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A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents.

• Authors : Tanaka-Kanegae R; Saga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Saga, Japan.; Hamada K

Subjects: Acetylcholine/Acetylcholine/Acetylcholine/*metabolism ; Cholinergic Agents/Cholinergic Agents/Cholinergic Agents/*pharmacology ; Neurons/Neurons/Neurons/*drug effects

• Source: PloS one [PLoS One] 2021 Oct 12; Vol. 16 (10), pp. e0258420. Date of Electronic Publication: 2021 Oct 12 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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The early excitatory action of striatal cholinergic-GABAergic microcircuits conditions the subsequent GABA inhibitory shift.

• Authors : Lozovaya N; B&A Therapeutics, Marseille, France.; Eftekhari S

Subjects: Inhibitory Postsynaptic Potentials*/Inhibitory Postsynaptic Potentials*/Inhibitory Postsynaptic Potentials*/physiology ; Cholinergic Agents*/Cholinergic Agents*/Cholinergic Agents*/pharmacology; Mice

• Source: Communications biology [Commun Biol] 2023 Jul 14; Vol. 6 (1), pp. 723. Date of Electronic Publication: 2023 Jul 14.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.

• Authors : Godavarthi, Swetha; Hiramoto, Masaki; Ignatyev, Yuri

Subjects: neurotransmitters; transmitter receptors; transmitter selection

• Source: Proceedings of the National Academy of Sciences. 121(15)

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Recent Advances in the Modulation of Cholinergic Signaling.

• Authors : Dallanoce C; Department of Pharmaceutical Sciences, Medicinal Chemistry Section 'Pietro Pratesi', University of Milan, Via L. Mangiagalli 25, 20133 Milan, Italy.

Subjects: Acetylcholine* ; Cholinergic Agents*/Cholinergic Agents*/Cholinergic Agents*/pharmacology; Humans

• Source: Molecules (Basel, Switzerland) [Molecules] 2022 Sep 14; Vol. 27 (18). Date of Electronic Publication: 2022 Sep 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents.

• Authors : Ryohei Tanaka-Kanegae; Koichiro Hamada

Subjects: Medicine; Science

• Source: PLoS ONE, Vol 16, Iss 10, p e0258420 (2021)

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Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

• Authors : Regeneron Pharmaceuticals

• Source: A Randomized, Double-blind, Placebo-controlled, Parallel-group, 52-week Pivotal Study to Assess the Efficacy, Safety, and Tolerability of Dupilumab in Patients With Moderate-to-severe Chronic

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M1 Schizophrenia PET Study

• Authors : National Institute of Mental Health (NIMH); Rajiv Radhakrishnan, MD, Assistant Professor of Psychiatry

• Source: Mogg AJ, Eessalu T, Johnson M, Wright R, Sanger HE, Xiao H, Crabtree MG, Smith A, Colvin EM, Schober D, Gehlert D, Jesudason C, Goldsmith PJ, Johnson MP, Felder CC, Barth VN, Broad LM. In Vitro

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Evaluation of Midazolam-Ketamine-Allopregnanolone Combination Therapy against Cholinergic-Induced Status Epilepticus in Rats.

• Authors : Nguyen, Donna; Stone, Michael; Schultz, Caroline

Subjects: Rats; Male; Animals

• Source: The Journal of Pharmacology and Experimental Therapeutics. 388(2)

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Postjunctional M2 Muscarinic Receptors Augment Neurally Mediated Cholinergic Contractions of Murine Airway Smooth Muscle.

• Authors : Ward SM; Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV 89557, USA.

Subjects: Receptors, Muscarinic*/Receptors, Muscarinic*/Receptors, Muscarinic*/physiology ; Cholinergic Agents*; Mice

• Source: Function (Oxford, England) [Function (Oxf)] 2021 Dec 23; Vol. 3 (1), pp. zqab067. Date of Electronic Publication: 2021 Dec 23 (Print Publication: 2022).Publisher: Oxford University Press Country of Publication: England NLM ID: 101770668 Publication Model: eCollection Cited Medium: Internet ISSN:

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