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Remarkable clinical responses of non-fluctuating Parkinson's disease (PD) after alternating catechol O-methyltransferase inhibitors: case series switching from entacapone 200 ~ 300 mg/day to opicapone 25 mg/day.

• Authors : Nakamagoe K; Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. .; Tsuji H

Subjects: Catechol O-Methyltransferase Inhibitors* ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy; Antiparkinson Agents

• Source: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2021 Nov; Vol. 42 (11), pp. 4813-4814. Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Catechol- O -methyltransferase Inhibitors from Calendula officinalis Leaf.

• Authors : Kadowaki W; Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.; Miyata R

Subjects: Calendula* ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy; Humans

• Source: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 30; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitors

• Authors : Martin Winter; Roman P. Simon; Yuting Wang

Subjects: MALDI-TOF; Label-free screening; High-throughput screening

• Source: SLAS Discovery, Vol 27, Iss 5, Pp 287-297 (2022)

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Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells.

• Authors : Grünig D; Division of Clinical Pharmacology & Toxicology, University Hospital Basel, 4031 Basel, Switzerland.; Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Subjects: Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/*pharmacology ; Catechols/Catechols/Catechols/*pharmacology ; Fatty Acids/Fatty Acids/Fatty Acids/*metabolism

• Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2018 Aug 01; Vol. 164 (2), pp. 477-488.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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Are There Benefits in Adding Catechol-O Methyltransferase Inhibitors in the Pharmacotherapy of Parkinson's Disease Patients? A Systematic Review.

• Authors : Katsaiti I; Current Medical Student, Lancaster Medical School, Lancaster, UK.; Nixon J

Subjects: Antiparkinson Agents/Antiparkinson Agents/Antiparkinson Agents/*therapeutic use ; Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/*therapeutic use ; Catechols/Catechols/Catechols/*therapeutic use

• Source: Journal of Parkinson's disease [J Parkinsons Dis] 2018; Vol. 8 (2), pp. 217-231.Publisher: IOS Press Country of Publication: Netherlands NLM ID: 101567362 Publication Model: Print Cited Medium: Internet ISSN: 1877-718X

تفاصيل العنوان

Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells

• Authors : Grünig, David; Felser, Andrea; Duthaler, Urs

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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.

• Authors : Byers S; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.; Buchler IP

Subjects: Catechol O-Methyltransferase/Catechol O-Methyltransferase/Catechol O-Methyltransferase/*metabolism ; Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/Catechol O-Methyltransferase Inhibitors/*pharmacology ; Cognition/Cognition/Cognition/*drug effects

• Source: Psychopharmacology [Psychopharmacology (Berl)] 2020 Sep; Vol. 237 (9), pp. 2695-2707. Date of Electronic Publication: 2020 May 30.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Catechol-O-methyltransferase Inhibitors from Calendula officinalis Leaf

• Authors : Wataru Kadowaki; Ryo Miyata; Misa Fujinami

Subjects: Calendula officinalis; flavonoid; phenylpropanoid

• Source: Molecules, Vol 28, Iss 3, p 1333 (2023)

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Two Faces of Catechol-O-Methyltransferase Inhibitor on One-Carbon Metabolism in Parkinson's Disease: A Meta-Analysis.

• Authors : Kim JH; Department of Biomedical and Pharmaceutical Science, Kyung Hee University, Seoul 02447, Republic of Korea.; Jin S

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/drug therapy ; Catechol O-Methyltransferase Inhibitors*/Catechol O-Methyltransferase Inhibitors*/Catechol O-Methyltransferase Inhibitors*/therapeutic use; Humans

• Source: Nutrients [Nutrients] 2023 Feb 10; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 10.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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Characterization of a unique catechol-O-methyltransferase as a molecular drug target in parasitic filarial nematodes.

• Authors : Mia MM; Department of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, United States of America.; Allaie IM

Subjects: Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/genetics ; Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/metabolism ; Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/chemistry

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Aug 30; Vol. 18 (8), pp. e0012473. Date of Electronic Publication: 2024 Aug 30 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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