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Characterization of a unique catechol-O-methyltransferase as a molecular drug target in parasitic filarial nematodes.

• Authors : Mia MM; Department of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, United States of America.; Allaie IM

Subjects: Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/genetics ; Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/metabolism ; Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/chemistry

• Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Aug 30; Vol. 18 (8), pp. e0012473. Date of Electronic Publication: 2024 Aug 30 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Association of catechol-o-methyltransferase gene polymorphism with preeclampsia and biomarkers of oxidative stress: Study protocol for a prospective case-control study in Pakistan.

• Authors : Yousuf, Farheen¹ (AUTHOR); Fatima, Tasneem² (AUTHOR); Rehman, Rehana³ (AUTHOR)

Subjects: *PREECLAMPSIA; *CATECHOL-O-methyltransferase gene; *GENETIC polymorphismsPAKISTAN

• Source: PLoS ONE. 6/11/2024, Vol. 19 Issue 6, p1-8. 8p.

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Integrated multiplexed assays of variant effect reveal determinants of catechol-O-methyltransferase gene expression.

• Authors : Hoskins I; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.; Rao S

Subjects: Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/genetics ; Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/Catechol O-Methyltransferase*/metabolism ; Machine Learning*

• Source: Molecular systems biology [Mol Syst Biol] 2024 May; Vol. 20 (5), pp. 481-505. Date of Electronic Publication: 2024 Feb 14.Publisher: Wiley Blackwell Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson's Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On.

• Authors : Männistö, Pekka T.¹ (AUTHOR); Keränen, Tapani² (AUTHOR); Reinikainen, Kari J.² (AUTHOR)

• Source: Neurology & Therapy. Aug2024, Vol. 13 Issue 4, p1039-1054. 16p.

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Catechol-O-Methyltransferase inhibition and alcohol use disorder: Evaluating the efficacy of tolcapone in ethanol-dependent rats.

• Authors : Doyle, Michelle; Dirik, Selen; Martinez, Angelica

Subjects: Alcohol use disorder; COMT; Estrous cycle

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The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson’s Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On

• Authors : Pekka T. Männistö; Tapani Keränen; Kari J. Reinikainen

Subjects: Catechol O-methyltransferase inhibition; Entacapone; Nitecapone

• Source: Neurology and Therapy, Vol 13, Iss 4, Pp 1039-1054 (2024)

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Estradiol and the Catechol-o-methyltransferase Gene Interact to Predict Working Memory Performance: A Replication and Extension.

• Authors : Louis, Courtney; Jacobs, Emily; Moser, Jason

Subjects: Humans; Female; Memory

• Source: Journal of Cognitive Neuroscience. 35(7)

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Unraveling Catechol-O-Methyltransferase rs4680 SNP's Role in Patients' Response to Tramadol and Its Adverse Effects: A Pharmacogenetics Insight into Postoperative Pain Management.

• Authors : Khan, Ammara¹ (AUTHOR) ; Waheed, Akbar² (AUTHOR); Afsar, Tayyaba³ (AUTHOR)

• Source: Journal of Clinical Medicine. Jan2024, Vol. 13 Issue 1, p249. 15p.

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Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol- O -Methyltransferase.

• Authors : Gonçalves, Ana M.^1,2,3 (AUTHOR); Pedro, Augusto Q.⁴ (AUTHOR); Oliveira, Diana M.¹ (AUTHOR)

Subjects: *CATECHOL-O-methyltransferase; *PARKINSON'S disease; *TREHALOSE

• Source: International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 20, p12298-N.PAG. 17p.

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Voltammetric measurement of catechol-O-methyltransferase inhibitor tolcapone in the pharmaceutical form on the boron-doped diamond electrode.

• Authors : KIRAN, Musa¹; YARDIM, Yavuz²

• Source: Turkish Journal of Chemistry. 2024, Vol. 48 Issue 1, p184-194. 13p.

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