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Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activation.

• Authors : Fujiwara, Ayana^1,2; Takemura, Keisuke^1,3; Tanaka, Anna²

• Source: Scientific Reports. 8/20/2024, Vol. 14 Issue 1, p1-12. 12p.

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Differential Expression of Circulating miRNAs and Carfilzomib-Related Cardiovascular Adverse Events in Patients with Multiple Myeloma.

• Authors : Tantawy, Marwa^1,2 (AUTHOR) ; Langaee, Taimour^1,2 (AUTHOR); Wang, Danxin^1,2 (AUTHOR)

Subjects: *GENE expression; *MULTIPLE myeloma; *MICRORNA

• Source: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7795. 15p.

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Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activation

• Authors : Ayana Fujiwara; Keisuke Takemura; Anna Tanaka

Subjects: Proteasome inhibitor; Carfilzomib; Hepatic stellate cell

• Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

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The Efficacy of Carfilzomib Treatment in Bortezomib-Refractory Patients—Real Life Experience in a Tertiary Romanian Hospital.

• Authors : Irimia, Ruxandra¹ (AUTHOR) ; Badelita, Sorina Nicoleta² (AUTHOR); Barbu, Sinziana^1,2 (AUTHOR)

• Source: Journal of Clinical Medicine. Apr2024, Vol. 13 Issue 8, p2171. 12p.

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A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2) (SUCCESSOR-2)

• Source: A Phase 3, Two-stage, Randomized, Multicenter, Open-label Study Comparing Mezigdomide (CC-92480/BMS-986348), Carfilzomib, and Dexamethasone (MeziKD) Versus

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Carfilzomib and dexamethasone maintenance following salvage ASCT in multiple myeloma: A randomised phase 2 trial by the Nordic Myeloma Study Group

• Authors : Gregersen, H; Peceliunas, V; Remes, K

Subjects: Medicin och hälsovetenskap

• Source: European journal of haematology. 108(1):34-44

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Carfilzomib activates ER stress and JNK/p38 MAPK signaling to promote apoptosis in hepatocellular carcinoma cells

• Authors : Deng Yao; Li Yujie; Yang Mingyue

Subjects: hepatocellular carcinoma; carfilzomib; ER stress

• Source: Acta Biochimica et Biophysica Sinica, Vol 56, Pp 697-708 (2024)

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Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma

• Source: A Phase I/II Study of Carfilzomib in Combination With R-CHOP (CR-CHOP) for Patients With Diffuse Large B-cell Lymphoma

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Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

• Authors : Janssen Scientific Affairs, LLC

• Source: A Phase 2 Adaptive Study of Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

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Selinexor, Daratumumab, Carfilzomib and Dexamethasone for the Treatment of High-Risk, Recurrent or Refractory Multiple Myeloma

• Authors : National Cancer Institute (NCI)

• Source: Open Label, Phase 2, Single-Arm Study of Selinexor, Daratumumab, Carfilzomib and Dexamethasone for High-Risk, Relapsed and Relapsed/Refractory Multiple Myeloma Patients

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