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A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity.

• Authors : Dongjun Liang^1,2; Kane Wu^1,2; Reika Tei^1,2

Subjects: *PHOSPHOLIPASE D; *CLICK chemistry; *G protein coupled receptors

• Source: Proceedings of the National Academy of Sciences of the United States of America. 7/30/2019, Vol. 116 Issue 31, p15453-15462. 10p.

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Click chemistry–enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling.

• Authors : Bumpus, Timothy W.¹; Shiying Huang¹; Tei, Reika¹

Subjects: *GLYCOGEN synthase kinase; *CRISPRS; *PROTEIN kinase C

• Source: Proceedings of the National Academy of Sciences of the United States of America. 11/30/2021, Vol. 118 Issue 48, p1-7. 7p.

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Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor.

• Authors : Hirose, Tomoyasu¹; Maita, Nobuo²; Gouda, Hiroaki³

Subjects: *CLICK chemistry; *CHITINASE; *RING formation (Chemistry)

• Source: Proceedings of the National Academy of Sciences of the United States of America. 10/1/2013, Vol. 110 Issue 40, p15892-15897. 6p.

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Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.

• Authors : Vaidya, Aditya S.^1,2; Peterson, Francis C.³; Eckhardt, James^1,2

Subjects: *ABSCISIC acid; *CLICK chemistry; *PLANT hormones

• Source: Proceedings of the National Academy of Sciences of the United States of America. 9/21/2021, Vol. 118 Issue 38, p1-7. 7p.

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Identification of simple arylfluorosulfates as potent agents against resistant bacteria.

• Authors : Jiong Zhang¹; Xiangxiang Zhao²; Cappiello, John R.³

Subjects: *CLICK chemistry; *ANTIBACTERIAL agents; *MULTIDRUG resistance

• Source: Proceedings of the National Academy of Sciences of the United States of America. 7/13/2021, Vol. 118 Issue 28, p1-7. 7p.

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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.

• Authors : Qinheng Zheng¹; Woehl, Jordan L.²; Kitamura, Seiya²

Subjects: *LEUCOCYTE elastase; *CLICK chemistry; *BIOLOGICAL assay

• Source: Proceedings of the National Academy of Sciences of the United States of America. 9/17/2019, Vol. 116 Issue 38, p18808-18814. 7p.

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Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.

• Authors : Greaves, Jennifer¹; Chamberlain, uke H.¹; Munro, Kevin R.²

Subjects: *ACYLATION; *FATTY acid analysis; *ZINC enzymes

• Source: Proceedings of the National Academy of Sciences of the United States of America. 2/21/2017, Vol. 114 Issue 8, pE1365-E1374. 10p.

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A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity

• Authors : Liang, Dongjun; Wu, Kane; Tei, Reika

Subjects: PNAS Plus

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Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry

• Authors : Luo, Haiming; Hernandez, Reinier; Hong, Hao

Subjects: Biological Sciences

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Semisynthetic protein nanoreactor for single-molecule chemistry.

• Authors : Joongoo Lee¹; Bayley, Hagan¹

Subjects: *SINGLE molecules; *CLICK chemistry; *ALKYNES

• Source: Proceedings of the National Academy of Sciences of the United States of America. 11/10/2015, Vol. 112 Issue 45, p13768-13773. 6p.

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