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Chemical synthesis of 2″OMeNAD+ and its deployment as an RNA 2′-phosphotransferase (Tpt1) 'poison' that traps the enzyme on its abortive RNA-2′-PO4-(ADP-2″OMe-ribose) reaction intermediate.

• Authors : Arnold, Jakob¹ (AUTHOR); Ghosh, Shreya² (AUTHOR); Kasprzyk, Renata¹ (AUTHOR)

Subjects: *ADENOSINE diphosphate ribose; *CHEMICAL synthesis; *POISONS

• Source: Nucleic Acids Research. 9/23/2024, Vol. 52 Issue 17, p10533-10542. 10p.

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Chemical Synthesis and Insecticidal Activity Research Based on α-Conotoxins.

• Authors : Lin C; Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education, International Joint Research Center of Human-Machine Intelligent Collaborative for Tumor Precision Diagnosis and Treatment of Hainan Province, Hainan Key Laboratory for Research and Development of Tropical Herbs, School of Pharmacy, Hainan Medical University, Haikou 571199, China.; Qin H

Subjects: Conotoxins*/Conotoxins*/Conotoxins*/chemistry ; Conotoxins*/Conotoxins*/Conotoxins*/pharmacology ; Conotoxins*/Conotoxins*/Conotoxins*/chemical synthesis

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 14; Vol. 29 (12). Date of Electronic Publication: 2024 Jun 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Discovery of Novel Thiazole-Based SIRT2 Inhibitors as Anticancer Agents: Molecular Modeling, Chemical Synthesis and Biological Assays.

• Authors : Piacente F; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV, 1, 16132 Genoa, Italy.; Guccione G

Subjects: Sirtuin 2*/Sirtuin 2*/Sirtuin 2*/antagonists & inhibitors ; Sirtuin 2*/Sirtuin 2*/Sirtuin 2*/chemistry ; Sirtuin 2*/Sirtuin 2*/Sirtuin 2*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 15; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Antimicrobial Properties of Flavonoid Derivatives with Bromine, Chlorine, and Nitro Group Obtained by Chemical Synthesis and Biotransformation Studies.

• Authors : Perz M; Department of Food Chemistry and Biocatalysis, Faculty of Biotechnology and Food Science, Wrocław University of Environmental and Life Sciences, 50-375 Wrocław, Poland.; Szymanowska D

Subjects: Flavonoids*/Flavonoids*/Flavonoids*/pharmacology ; Flavonoids*/Flavonoids*/Flavonoids*/chemistry ; Flavonoids*/Flavonoids*/Flavonoids*/chemical synthesis

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 19; Vol. 25 (10). Date of Electronic Publication: 2024 May 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Chemical Synthesis of Atactic Poly-3-hydroxybutyrate (a-P3HB) by Self-Polycondensation: Catalyst Screening and Characterization.

• Authors : Almustafa, Wael¹ (AUTHOR) ; Schubert, Dirk W.² (AUTHOR); Grishchuk, Sergiy¹ (AUTHOR)

Subjects: *POLY-beta-hydroxybutyrate; *CHEMICAL synthesis; *FOURIER transform infrared spectroscopy

• Source: Polymers (20734360). Jun2024, Vol. 16 Issue 12, p1655. 12p.

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SMILES-Prompting: A Novel Approach to LLM Jailbreak Attacks in Chemical Synthesis

• Authors : Wong, Aidan; Cao, He; Liu, Zijing

Subjects: Computer Science - Computation and Language

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Facile Solid-State Chemical Synthesis of CoMoO 4 Nanorods for High-Performance Supercapacitors.

• Authors : Yu, Rui¹ (AUTHOR); Lu, Xiaoyan¹ (AUTHOR); Lu, Zhenjiang¹ (AUTHOR)

Subjects: *CHEMICAL synthesis; *NANORODS; *X-ray powder diffraction

• Source: Molecules. Mar2024, Vol. 29 Issue 6, p1369. 12p.

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Microbiological Bioreduction of Bulky–Bulky Pyrimidine Derivatives as an Alternative to Asymmetric Chemical Synthesis.

• Authors : Kołodziejska, Renata¹ (AUTHOR) ; Pawluk, Hanna¹ (AUTHOR); Tafelska-Kaczmarek, Agnieszka² (AUTHOR)

• Source: Catalysts (2073-4344). Oct2024, Vol. 14 Issue 10, p667. 17p.

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Enhancing chemical synthesis: a two-stage deep neural network for predicting feasible reaction conditions.

• Authors : Chen, Lung-Yi¹ (AUTHOR); Li, Yi-Pei^1,2 (AUTHOR)

• Source: Journal of Cheminformatics. 1/24/2024, Vol. 16 Issue 1, p1-14. 14p.

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Recent Developments in Reactor Automation for Multistep Chemical Synthesis.

• Authors : Clayton, Adam D.¹ (AUTHOR)

• Source: Chemistry - Methods. Dec2023, Vol. 3 Issue 12, p1-12. 12p.

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