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  • 1-10 ل  1,537 نتائج ل ""CASP8 and FADD-Like Apoptosis Regulating Protein""

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Academic Journal

Pharmacological targeting of caspase-8/c-FLIP L heterodimer enhances complex II assembly and elimination of pancreatic cancer cells.

  • Authors : König C; Translational Inflammation Research, Medical Faculty, Otto von Guericke University (OvGU), Magdeburg, Magdeburg, Germany.; Ivanisenko NV

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology

  • Source: Communications biology [Commun Biol] 2025 Jan 03; Vol. 8 (1), pp. 4. Date of Electronic Publication: 2025 Jan 03.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNA-Seq Reveals Transcriptome Changes Following Zika Virus Infection in Fetal Brains in c-Flip Knockdown Mice.

  • Authors : Xie T; School of Public Health (Shenzhen), Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.; School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou 510275, China.

Subjects: Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/virology ; Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/genetics ; Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/metabolism

  • Source: Viruses [Viruses] 2024 Oct 31; Vol. 16 (11). Date of Electronic Publication: 2024 Oct 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Dichloroacetate reduces cisplatin-induced apoptosis by inhibiting the JNK/14-3-3/Bax/caspase-9 pathway and suppressing caspase-8 activation via cFLIP in murine tubular cells.

  • Authors : Kimura H; Department of Clinical Laboratory, University of Fukui Hospital, 23-3 Matsuoka-shimoaizuki, Eiheiji-Cho, Yoshida, Fukui, 910-1193, Japan. .; Division of Nephrology, Department of General Medicine, School of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan. .

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/adverse effects ; Cisplatin*/Cisplatin*/Cisplatin*/pharmacology ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

  • Source: Scientific reports [Sci Rep] 2024 Oct 16; Vol. 14 (1), pp. 24307. Date of Electronic Publication: 2024 Oct 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

c-FLIP facilitates ZIKV infection by mediating caspase-8/3-dependent apoptosis.

  • Authors : Zhang S; School of Public Health (Shenzhen), Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, P.R. China.; School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, P.R. China.

Subjects: Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/virology ; Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/metabolism ; Zika Virus Infection*/Zika Virus Infection*/Zika Virus Infection*/pathology

  • Source: PLoS pathogens [PLoS Pathog] 2024 Jul 22; Vol. 20 (7), pp. e1012408. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Mef2c Exacerbates Neuron Necroptosis via Modulating Alternative Splicing of Cflar in Ischemic Stroke With Hyperlipidemia.

  • Authors : Li R; Cerebrovascular Diseases Center, Department of Neurosurgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Huang T

Subjects: MEF2 Transcription Factors*/MEF2 Transcription Factors*/MEF2 Transcription Factors*/metabolism ; MEF2 Transcription Factors*/MEF2 Transcription Factors*/MEF2 Transcription Factors*/genetics ; Hyperlipidemias*/Hyperlipidemias*/Hyperlipidemias*/genetics

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Dec; Vol. 30 (12), pp. e70144.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Xanthatin induces apoptosis through ROS-mediated c-FLIP inhibition in human retinoblastoma cells

Subjects: retinoblastoma; xanthatin; apoptosis

  • Source: Frontiers in Medicine, Vol 12 (2025)

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Academic Journal

Interaction between the Hepatitis B Virus and Cellular FLIP Variants in Viral Replication and the Innate Immune System.

  • Authors : Lee AR; Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon 16419, Korea.; Park YK

Subjects: Host-Pathogen Interactions* ; Virus Replication*; CASP8 and FADD-Like Apoptosis Regulating Protein/CASP8 and FADD-Like Apoptosis Regulating Protein/CASP8 and FADD-Like Apoptosis Regulating Protein/*metabolism

  • Source: Viruses [Viruses] 2022 Feb 11; Vol. 14 (2). Date of Electronic Publication: 2022 Feb 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Mathematical Modeling Reveals the Importance of the DED Filament Composition in the Effects of Small Molecules Targeting Caspase-8/c-FLIP L Heterodimer.

  • Authors : Ivanisenko NV; Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. .; Lavrik IN

Subjects: CASP8 and FADD-Like Apoptosis Regulating Protein*/CASP8 and FADD-Like Apoptosis Regulating Protein*/CASP8 and FADD-Like Apoptosis Regulating Protein*/antagonists & inhibitors ; CASP8 and FADD-Like Apoptosis Regulating Protein*/CASP8 and FADD-Like Apoptosis Regulating Protein*/CASP8 and FADD-Like Apoptosis Regulating Protein*/chemistry ; Models, Theoretical*

  • Source: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Oct; Vol. 85 (10), pp. 1134-1144.Publisher: MAIK Nauka/Interperiodica Country of Publication: United States NLM ID: 0376536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Wilms’ tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP

Subjects: Biomedical and Clinical Sciences; Immunology; Sexually Transmitted Infections

  • Source: PLOS Pathogens. 20(1)

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Academic Journal

Oncogenic signaling inhibits c-FLIP L expression and its non-apoptotic function during ECM-detachment.

  • Authors : Tsegaye MA; Department of Biological Sciences, University of Notre Dame, 222 Galvin Life Science Center, Notre Dame, IN, 46556, USA.; Integrated Biomedical Sciences Program, University of Notre Dame, Notre Dame, IN, 46556, USA.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; CASP8 and FADD-Like Apoptosis Regulating Protein/CASP8 and FADD-Like Apoptosis Regulating Protein/CASP8 and FADD-Like Apoptosis Regulating Protein/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Sep 20; Vol. 11 (1), pp. 18606. Date of Electronic Publication: 2021 Sep 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  1,537 نتائج ل ""CASP8 and FADD-Like Apoptosis Regulating Protein""