نتائج البحث

Adult and pediatric physiologically‐based biopharmaceutics modeling to explain lamotrigine immediate release absorption process.

• Authors : Caleffi‐Marchesini, Edilainy Rizzieri¹ (AUTHOR); Herling, Amanda Antunes¹ (AUTHOR); Macente, Julia¹ (AUTHOR)

• Source: CPT: Pharmacometrics & Systems Pharmacology. Feb2024, Vol. 13 Issue 2, p208-221. 14p.

تفاصيل العنوان

Physiologically Based Biopharmaceutics Model (PBBM) of Minimally Absorbed Locally Acting Drugs in the Gastrointestinal Tract—Case Study: Tenapanor.

• Authors : Stamatopoulos, Konstantinos¹ (AUTHOR) ; Mistry, Nena¹ (AUTHOR); Fotaki, Nikoletta² (AUTHOR)

• Source: Pharmaceutics. Dec2023, Vol. 15 Issue 12, p2726. 16p.

تفاصيل العنوان

In Vivo Predictive Dissolution and Biopharmaceutic-Based In Silico Model to Explain Bioequivalence Results of Valsartan, a Biopharmaceutics Classification System Class IV Drug.

• Authors : Gonzalez-Alvarez, Isabel¹ (AUTHOR) ; Ruiz-Picazo, Alejandro¹ (AUTHOR) ; Selles-Talavera, Ruben¹ (AUTHOR)

• Source: Pharmaceutics. Mar2024, Vol. 16 Issue 3, p390. 14p.

تفاصيل العنوان

Biopharmaceutics and Drug Hypersensitivity

• Authors : Pinzini, John; Mossillo, Paul

Subjects: Biopharmaceutics; Drug allergyMEDICAL / Pharmacology

تفاصيل العنوان

Parameterization of Physiologically Based Biopharmaceutics Models: Workshop Summary Report

• Authors : Pepin, Xavier; Arora, Sumit; Borges, Luiza

Subjects: PBBM; biopredictive dissolution; permeability

• Source: Molecular Pharmaceutics. 21(8):3697-3731

تفاصيل العنوان

Tipifarnib physiologically-based pharmacokinetic modeling to assess drug-drug interaction, organ impairment, and biopharmaceutics in healthy subjects and cancer patients.

• Authors : Okudaira N; Certara, UK Ltd. (Simcyp Division), Sheffield, UK.; Burt H

Subjects: Drug Interactions* ; Models, Biological* ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

• Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Aug; Vol. 13 (8), pp. 1366-1379. Date of Electronic Publication: 2024 May 28.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Integrating In Vitro Biopharmaceutics into Physiologically Based Biopharmaceutic Model (PBBM) to Predict Food Effect of BCS IV Zwitterionic Drug (GSK3640254).

• Authors : Stamatopoulos, Konstantinos¹ (AUTHOR) ; Ferrini, Paola² (AUTHOR); Nguyen, Dung³ (AUTHOR)

• Source: Pharmaceutics. Feb2023, Vol. 15 Issue 2, p521. 26p.

تفاصيل العنوان

Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A Retrospective Case Study of the Utility for Formulation Bridging.

• Authors : Belubbi, Tejashree¹ (AUTHOR); Bassani, Davide¹ (AUTHOR); Stillhart, Cordula² (AUTHOR)

• Source: Pharmaceutics. Jan2023, Vol. 15 Issue 1, p191. 11p.

تفاصيل العنوان

Tipifarnib physiologically‐based pharmacokinetic modeling to assess drug–drug interaction, organ impairment, and biopharmaceutics in healthy subjects and cancer patients

• Authors : Noriko Okudaira; Howard Burt; Amitava Mitra

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 8, Pp 1366-1379 (2024)

تفاصيل العنوان

Biopharmaceutics considerations for direct oral anticoagulants.

• Authors : de Andrade, Rafael Pereira (AUTHOR); Caldeira, Tamires Guedes (AUTHOR); Vasques, Bárbara Vasconcelos (AUTHOR)

Subjects: GENERIC drugs; ORAL medication; BIOPHARMACEUTICS

• Source: Drug Development & Industrial Pharmacy. Dec2021, Vol. 47 Issue 12, p1881-1894. 14p.

تفاصيل العنوان