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Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway.

• Authors : Zhao L; Guizhou Medical University, Guiyang, 550004, Guizhou, China.; Department of Ultrasound Center, The Affiliated Hospital of Guizhou Medical University, NO.28 Guiyi Street, Guiyang, 550004, Guizhou, China.

Subjects: Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/metabolism ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/pathology ; Apoptosis*

• Source: Scientific reports [Sci Rep] 2024 Dec 30; Vol. 14 (1), pp. 31915. Date of Electronic Publication: 2024 Dec 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Recombinant human annexin A5 accelerates diabetic wounds healing by regulating skin inflammation

• Authors : Bijun Kang; Zhuoxuan Jia; Yushan Dong

Subjects: Annexin A5; Macrophage; Diabetic wound healing

• Source: Regenerative Therapy, Vol 27, Iss , Pp 342-353 (2024)

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Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion

• Authors : InFocus Clinical Research

• Source: Open-label, Dose Ascending Safety, Tolerability, and Proof of Concept Study to Evaluate the Use of ANXV (Human Recombinant Annexin A5) in

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Phosphatidylserine on sperm head interact with Annexin A5 on oviduct luminal cilia to form a sperm reservoir in pigs

• Authors : Lorraine Schmaltz; Elie Barakat; Renaud Fleurot

Subjects: Spermatozoa; Oviduct; Phosphatidylserine

• Source: European Journal of Cell Biology, Vol 104, Iss 1, Pp 151471- (2025)

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The Relevance, Predictability, and Utility of Annexin A5 for Human Physiopathology.

• Authors : Jing, Jian¹ (AUTHOR)

Subjects: *PATHOLOGICAL physiology; *ANNEXINS; *PHOSPHATIDYLSERINES

• Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2865. 21p.

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Annexin A5 in Patients With Severe COVID-19 Disease (AX-COVID)

• Authors : Ontario Ministry of Colleges and Universities; London Health Sciences Foundation

• Source: Annexin A5 in Patients With Severe COVID-19 Disease: A Single Centre, Randomized, Double-blind, Placebo-controlled Pilot Trial

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Annexin A5 stabilizes matrix vesicle-biomimetic lipid membranes: unravelling a new role of annexins in calcification.

• Authors : Ferreira, Claudio R.¹ (AUTHOR); Cruz, Marcos Antônio E.¹ (AUTHOR); Bolean, Maytê¹ (AUTHOR)

• Source: European Biophysics Journal. Nov2023, Vol. 52 Issue 8, p721-733. 13p.

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Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19

• Authors : Brent J. Tschirhart; Xiangru Lu; Aristide Laurel Mokale Kognou

Subjects: COVID-19; sepsis; annexin A5

• Source: Frontiers in Pharmacology, Vol 14 (2024)

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Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding.

• Authors : Tschirhart, Brent J.¹ (AUTHOR); Lu, Xiangru¹ (AUTHOR); Gomes, Janice² (AUTHOR)

• Source: Pharmaceuticals (14248247). Jun2023, Vol. 16 Issue 6, p837. 14p.

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Method of treating skin tissue damage by topically administering a bi-specific protein comprising a human insulin-like growth factor variant and a human annexin A5 variant

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