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Academic Journal

Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae.

Authors : Kumar A; Department of Biotechnology, Sharda School of Engineering and Technology, Sharda University, Greater Noida, Uttar Pradesh, India.; Anjum F

Subjects: Klebsiella pneumoniae*/Klebsiella pneumoniae*/Klebsiella pneumoniae*/enzymology ; Klebsiella pneumoniae*/Klebsiella pneumoniae*/Klebsiella pneumoniae*/drug effects ; Amino Acid Isomerases*/Amino Acid Isomerases*/Amino Acid Isomerases*/antagonists & inhibitors

Source: PloS one [PLoS One] 2025 Feb 06; Vol. 20 (2), pp. e0317622. Date of Electronic Publication: 2025 Feb 06 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

d-amino acid auxotrophic Escherichia coli strain for in vivo functional cloning of novel d-amino acid synthetic enzyme.

Authors : Ito T; Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Japan.; Muto N

Subjects: Amino Acids*/Amino Acids*/Amino Acids*/genetics ; Amino Acids*/Amino Acids*/Amino Acids*/metabolism ; Amino Acid Isomerases*/Amino Acid Isomerases*/Amino Acid Isomerases*/genetics

Source: The FEBS journal [FEBS J] 2023 Jun; Vol. 290 (11), pp. 2895-2908. Date of Electronic Publication: 2023 Feb 08.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

The conundrum in enzymatic reactions related to biosynthesis of d-amino acids in bacteria.

Authors : Pollegioni L; 'The Protein Factory 2.0', Dipartimento di Biotecnologie e Scienze della Vita, Università degli studi dell'Insubria, Varese, Italy.; Molla G

Subjects: Amino Acid Isomerases*/Amino Acid Isomerases*/Amino Acid Isomerases*/genetics ; Amino Acid Isomerases*/Amino Acid Isomerases*/Amino Acid Isomerases*/metabolism; Amino Acids/Amino Acids/Amino Acids/metabolism

Source: The FEBS journal [FEBS J] 2022 Oct; Vol. 289 (19), pp. 5895-5898. Date of Electronic Publication: 2022 May 19.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Microbial Proline Racemase-Proline Dehydrogenase Cascade for Efficient Production of D-proline and N-boc-5-hydroxy-L-proline from L-proline.

Authors : Zhang F; Chongqing Key Laboratory of Big Data On Bio-Intelligence, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, People's Republic of China.; Xia S

Subjects: Amino Acid Isomerases* ; Proline*; Escherichia coli/Escherichia coli/Escherichia coli/genetics

Source: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2022 Sep; Vol. 194 (9), pp. 4135-4146. Date of Electronic Publication: 2022 May 30.Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile.

Authors : Gateau C; AP-HP, Hôpital saint Antoine, National Reference Laboratory for Clostridioides Difficile, Paris, France.; Université de Paris, INSERM, UMR-S 1139, Paris, France.

Subjects: Amino Acid Isomerases*/Amino Acid Isomerases*/Amino Acid Isomerases*/antagonists & inhibitors ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Clostridioides difficile*/Clostridioides difficile*/Clostridioides difficile*/drug effects

Source: Chemical biology & drug design [Chem Biol Drug Des] 2022 Apr; Vol. 99 (4), pp. 513-526. Date of Electronic Publication: 2022 Jan 05.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Significance of Glutamate Racemase for the Viability and Cell Wall Integrity of Streptococcus iniae.

Authors : Muhammad M; College of Life Science, Hebei Normal University, Shijiazhuang, 050024, China.; Kano University of Science and Technology, Department of Biochemistry, Wudil, Nigeria.

Subjects: Cell Wall*/Cell Wall*/Cell Wall*/drug effects ; Cell Wall*/Cell Wall*/Cell Wall*/metabolism ; Microbial Viability*/Microbial Viability*/Microbial Viability*/drug effects

Source: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Feb; Vol. 85 (2), pp. 248-256.Publisher: MAIK Nauka/Interperiodica Country of Publication: United States NLM ID: 0376536 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

SRL pathogenicity island contributes to the metabolism of D-aspartate via an aspartate racemase in Shigella flexneri YSH6000.

Authors : Henríquez T; Programa de Microbiología y Micología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile.; Biozentrum, Ludwig-Maximilians-Universität München, Martinsried, Germany.

Subjects: Genomic Islands*; Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*metabolism ; D-Aspartic Acid/D-Aspartic Acid/D-Aspartic Acid/*metabolism

Source: PloS one [PLoS One] 2020 Jan 24; Vol. 15 (1), pp. e0228178. Date of Electronic Publication: 2020 Jan 24 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Ethambutol targets the glutamate racemase of Mycobacterium tuberculosis-an enzyme involved in peptidoglycan biosynthesis.

Authors : Pawar A; Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India.; Bhaskaracharya College of Applied Sciences, University of Delhi, Delhi, 110075, India.

Subjects: Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*antagonists & inhibitors ; Antitubercular Agents/Antitubercular Agents/Antitubercular Agents/*pharmacology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2019 Jan; Vol. 103 (2), pp. 843-851. Date of Electronic Publication: 2018 Nov 19.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Elucidation of the d-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima.

Authors : Miyamoto T; Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.; Katane M

Subjects: Gene Expression Regulation, Bacterial*; Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*metabolism ; Cell Wall/Cell Wall/Cell Wall/*enzymology

Source: The FEBS journal [FEBS J] 2019 Feb; Vol. 286 (3), pp. 601-614. Date of Electronic Publication: 2018 Dec 28.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.

Authors : Gao A; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.; Vasilyev N

Subjects: Acid Anhydride Hydrolases/Acid Anhydride Hydrolases/Acid Anhydride Hydrolases/*chemistry ; Acid Anhydride Hydrolases/Acid Anhydride Hydrolases/Acid Anhydride Hydrolases/*metabolism ; Amino Acid Isomerases/Amino Acid Isomerases/Amino Acid Isomerases/*chemistry

Source: Nucleic acids research [Nucleic Acids Res] 2018 Jul 27; Vol. 46 (13), pp. 6841-6856.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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نتائج البحث

فلترة النتائج

Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae.

d-amino acid auxotrophic Escherichia coli strain for in vivo functional cloning of novel d-amino acid synthetic enzyme.

The conundrum in enzymatic reactions related to biosynthesis of d-amino acids in bacteria.

Microbial Proline Racemase-Proline Dehydrogenase Cascade for Efficient Production of D-proline and N-boc-5-hydroxy-L-proline from L-proline.

Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile.

Significance of Glutamate Racemase for the Viability and Cell Wall Integrity of Streptococcus iniae.

SRL pathogenicity island contributes to the metabolism of D-aspartate via an aspartate racemase in Shigella flexneri YSH6000.

Ethambutol targets the glutamate racemase of Mycobacterium tuberculosis-an enzyme involved in peptidoglycan biosynthesis.

Elucidation of the d-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima.

Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.

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