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Academic Journal

Effects of rivastigmine on gait in patients with neurodegenerative disorders: A systematic review and meta-analysis.

  • Authors : Shim SR; Department of Biomedical Informatics, Konyang University College of Medicine, Daejeon, Republic of Korea.; Kim JY

Subjects: Accidental Falls*/Accidental Falls*/Accidental Falls*/prevention & control ; Accidental Falls*/Accidental Falls*/Accidental Falls*/statistics & numerical data ; Gait*/Gait*/Gait*/drug effects

  • Source: PloS one [PLoS One] 2024 Dec 12; Vol. 19 (12), pp. e0310900. Date of Electronic Publication: 2024 Dec 12 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Inhibitory Effects of Gliadin Hydrolysates on BACE1 Expression and APP Processing to Prevent Aβ Aggregation.

  • Authors : Lin CY; Department of Biomedical Sciences and Engineering, Tzu Chi University, No. 701, Sec. 3, Zhongyang Rd., Hualien City 970374, Taiwan.; Hsieh CH

Subjects: Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/metabolism ; Aspartic Acid Endopeptidases*/Aspartic Acid Endopeptidases*/Aspartic Acid Endopeptidases*/metabolism ; Gliadin*/Gliadin*/Gliadin*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 09; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Network Pharmacology, Molecular Docking, and In Vitro Insights into the Potential of Mitragyna speciosa for Alzheimer's Disease.

  • Authors : Hossain R; College of Graduate Studies, Walailak University, Nakhon Si Thammarat 80160, Thailand.; School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Molecular Docking Simulation*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 08; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Glutamate: Molecular Mechanisms and Signaling Pathway in Alzheimer's Disease, a Potential Therapeutic Target.

  • Authors : Puranik N; Department of Life Sciences, Yeungnam University, Gyeongsan 38541, Republic of Korea.; Song M

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 05; Vol. 29 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Identification of AChE targeted therapeutic compounds for Alzheimer's disease: an in-silico study with DFT integration.

  • Authors : Rawat K; Computational Biology and Biotechnology Laboratory, Department of Botany, Soban Singh Jeena University, Almora, Uttarakhand, India.; Tewari D

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/chemistry

  • Source: Scientific reports [Sci Rep] 2024 Dec 05; Vol. 14 (1), pp. 30356. Date of Electronic Publication: 2024 Dec 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chelating Properties of N 6 O-Donors Toward Cu(II) Ions: Speciation in Aqueous Environments and Catalytic Activity of the Dinuclear Complexes.

  • Authors : Cendron A; Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131 Padova, Italy.; Chianese M

Subjects: Copper*/Copper*/Copper*/chemistry ; Chelating Agents*/Chelating Agents*/Chelating Agents*/chemistry ; Chelating Agents*/Chelating Agents*/Chelating Agents*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 03; Vol. 29 (23). Date of Electronic Publication: 2024 Dec 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Behavioral and Biochemical Effects of an Arylhydrazone Derivative of 5-Methoxyindole-2-Carboxylic Acid in a Scopolamine-Induced Model of Alzheimer's Type Dementia in Rats.

  • Authors : Petkova-Kirova P; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113 Sofia, Bulgaria.; Anastassova N

Subjects: Scopolamine*/Scopolamine*/Scopolamine*/adverse effects ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 03; Vol. 29 (23). Date of Electronic Publication: 2024 Dec 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Evaluating Blood-Brain Barrier Permeability, Cytotoxicity, and Activity of Potential Acetylcholinesterase Inhibitors: In Vitro and In Silico Study.

  • Authors : Maboko LM; Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.; Theron A

Subjects: Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/metabolism ; Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/drug effects ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/pharmacology

  • Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Dec; Vol. 12 (6), pp. e70043.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Academic Journal

Integrating network pharmacology and experimental validation to investigate the effects and mechanism of Renshen Shouwu decoction for ameliorating Alzheimer's disease.

  • Authors : Liu JJ; Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; National Institutes for Food and Drug Control, Beijing, China.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/pharmacology ; Network Pharmacology*

  • Source: Pharmaceutical biology [Pharm Biol] 2024 Dec; Vol. 62 (1), pp. 767-780. Date of Electronic Publication: 2024 Oct 17.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploring the protective effect and molecular mechanism of betulin in Alzheimer's disease based on network pharmacology, molecular docking and experimental validation.

  • Authors : Wang N; Laboratory of Brain and Cognitive Science, School of Basic Medical Sciences, Dali University, Dali, Yunnan 671003, P.R. China.; Cui J

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Molecular Docking Simulation*

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Dec; Vol. 30 (6). Date of Electronic Publication: 2024 Oct 11.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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