نتائج البحث

Alpha-synuclein and neuromelanin interplay: unravelling its role in the pathophysiology of Parkinson’s disease

• Authors : Nicolau Vera, Alba;

Subjects: Neuromelanina; Neuromelanin; Parkinson616.8

• Source: TDX (Tesis Doctorals en Xarxa)

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Alpha-Synuclein and Microglia in Parkinson's Disease: From Pathogenesis to Therapeutic Prospects.

• Authors : Eo, Hyemi¹ (AUTHOR) ; Kim, Sehwan¹ (AUTHOR) ; Jung, Un Ju² (AUTHOR)

• Source: Journal of Clinical Medicine. Dec2024, Vol. 13 Issue 23, p7243. 20p.

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Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease.

• Authors : Brown, Ethan; Chahine, Lana; Siderowf, Andrew

Subjects: Humans; Male; Female

• Source: Annals of Neurology. 97(4)

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A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies.

• Authors : Koss DJ; Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK. .; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK. .

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Lewy Body Disease*/Lewy Body Disease*/Lewy Body Disease*/pathology

• Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Mar 20; Vol. 20 (1), pp. 34. Date of Electronic Publication: 2025 Mar 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Oligodendrocyte-specific overexpression of human alpha-synuclein results in elevated MBP levels and inflammatory responses in TgM83 mice, mimicking the pathological features of multiple system atrophy.

• Authors : Liu SC; Department of Neurology, National Taiwan University College of Medicine, No.1, Jen Ai Road section 1, Taipei City, Taiwan (R.O.C.).; Department of Neurology, National Taiwan University Hospital, No.7, Chung Shan South Road, Taipei City, Taiwan (R.O.C.).

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; Multiple System Atrophy*/Multiple System Atrophy*/Multiple System Atrophy*/pathology

• Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 May 07; Vol. 13 (1), pp. 94. Date of Electronic Publication: 2025 May 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Effect of hydrogen sulfide on alpha-synuclein aggregation and cell viability.

• Authors : Ostrakhovitch EA; Department of Neurology, University of Kentucky, 740 South Limestone St., Ste. J401, Lexington, KY, 40536-0284, USA.; Veterans Affairs, Lexington, KY, 40536, USA.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry

• Source: Scientific reports [Sci Rep] 2025 May 04; Vol. 15 (1), pp. 15597. Date of Electronic Publication: 2025 May 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Mechanistic insights into Alpha-Synuclein binding to P2RX7: A molecular dynamic and docking study.

• Authors : Kumar M; ICAR-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh, India.; Singh K

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry ; Receptors, Purinergic P2X7*/Receptors, Purinergic P2X7*/Receptors, Purinergic P2X7*/metabolism

• Source: PloS one [PLoS One] 2025 May 02; Vol. 20 (5), pp. e0319098. Date of Electronic Publication: 2025 May 02 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Alpha-synuclein RT-QuIC assay in gastroduodenal and skin biopsies of Parkinson disease patients.

• Authors : Emmi A; Parkinson and Movement Disorders Unit, Department of Neuroscience, Centre for Rare Neurological Diseases (ERN-RND), University of Padova, Padova, Italy.; Center for Neurodegenerative Disease Research (CESNE), University of Padova, Padova, Italy.

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/metabolism ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/diagnosis

• Source: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2025 Mar; Vol. 12 (3), pp. 637-642. Date of Electronic Publication: 2024 Dec 21.Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model:

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Associations between misfolded alpha-synuclein aggregates and Alzheimer's disease pathology in vivo

• Authors : Pichet Binette, Alexa; Mammana, Angela; Wisse, Laura ...

Subjects: Medical and Health Sciences; Basic Medicine; Neurosciences

• Source: Alzheimer's and Dementia. 20(11):7624-7634

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Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer's disease.

• Authors : Franzmeier N; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany. .; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. .

Subjects: tau Proteins*/tau Proteins*/tau Proteins*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology

• Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Mar 18; Vol. 20 (1), pp. 31. Date of Electronic Publication: 2025 Mar 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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