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Alkylating agents-induced gonadotoxicity in prepubertal males: Insights on the clinical and preclinical front.

• Authors : Sriram S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Macedo T

Subjects: Testis*/Testis*/Testis*/drug effects ; Antineoplastic Agents, Alkylating*/Antineoplastic Agents, Alkylating*/Antineoplastic Agents, Alkylating*/adverse effects ; Antineoplastic Agents, Alkylating*/Antineoplastic Agents, Alkylating*/Antineoplastic Agents, Alkylating*/administration & dosage

• Source: Clinical and translational science [Clin Transl Sci] 2024 Jul; Vol. 17 (7), pp. e13866.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans.

• Authors : Ruszkiewicz, Joanna¹ (AUTHOR) ; Endig, Lisa¹ (AUTHOR); Güver, Ebru¹ (AUTHOR)

• Source: Cells (2073-4409). Dec2023, Vol. 12 Issue 23, p2728. 16p.

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Novel MGMT inhibitors increase the sensitivity of glioma MGMT-positive cells to treatment with alkylating agents in vitro.

• Authors : Zhuvaka, K. S.¹ ; Piven, O. О.¹; Macewicz, L. L.¹

• Source: Biopolymers & Cell. 2024, Vol. 40 Issue 1, p47-57. 11p.

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The study of force fields molecular mechanics and molecular quantum on the interaction with drugs of the alkylating agent with SWCNT-BNNT in different solvents and at different temperatures.

• Authors : Jamshidi, Mohammad Hassan¹ ; Hasanzadeh, Neda¹ ; Yahyaei, Hooriye²

• Source: Indian Journal of Chemistry (0019-5103). Jan2024, Vol. 63 Issue 1, p80-93. 14p.

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Computational studies of DNA damage and repair of alkylating agents and UV light

• Authors : Kranas, Hanna; University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida; ...

Subjects: DNA damage; DNA repair mechanisms; Mutagenic processes

• Source: TDX (Tesis Doctorals en Xarxa)

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Conformational Modulation of Tissue Transglutaminase via Active Site Thiol Alkylating Agents: Size Does Not Matter.

• Authors : Navals, Pauline¹ (AUTHOR) ; Rangaswamy, Alana M. M.¹ (AUTHOR); Kasyanchyk, Petr¹ (AUTHOR)

• Source: Biomolecules (2218-273X). Apr2024, Vol. 14 Issue 4, p496. 14p.

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Multi-Omics Analysis of NCI-60 Cell Line Data Reveals Novel Metabolic Processes Linked with Resistance to Alkylating Anti-Cancer Agents.

• Authors : Rushing, Blake R.^1,2,3,4 (AUTHOR)

Subjects: *ALKYLATING agents; *MULTIOMICS; *ANTINEOPLASTIC agents

• Source: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 17, p13242. 19p.

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Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients

• Authors : Cui, YH; Harteveld, F; Omar, HAMB

Subjects: Medicin och hälsovetenskap

• Source: Human reproduction open. 2024(3)

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Combination Therapy with Immune Checkpoint Inhibitors and Histone Deacetylase Inhibitors or Alkylating Agents

• Authors : Joerger M; Koster KL; Janik T

Subjects: histone deacetylase inhibitor; checkpoint inhibitor; alkylating agents

• Source: Cancer Management and Research, Vol Volume 16, Pp 855-869 (2024)

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Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies

• Source: A Phase 1 Trial to Investigate the Safety, Pharmacokinetic Profiles and the Efficacy of Tinostamustine, a First-in-Class Alkylating Histone Deacetylase Inhibition

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