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Academic Journal

Polypeptide Substrate Accessibility Hypothesis: Gain-of-Function R206H Mutation Allosterically Affects Activin Receptor-like Protein Kinase Activity.

Authors : Groppe JC; Department of Biomedical Sciences, Texas A&M University College of Dentistry, 3302 Gaston Ave, Dallas, TX 75246, USA.; Lu G

Subjects: Gain of Function Mutation* ; Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/genetics ; Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/metabolism

Source: Biomolecules [Biomolecules] 2023 Jul 14; Vol. 13 (7). Date of Electronic Publication: 2023 Jul 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

AAV-Mediated Targeting of the Activin A-ACVR1 R206H Signaling in Fibrodysplasia Ossificans Progressiva.

Authors : Yang YS; Department of Medicine, Division of Rheumatology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.; Lin C

Subjects: Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/genetics ; Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/genetics ; Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/therapy

Source: Biomolecules [Biomolecules] 2023 Sep 08; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.

Authors : Quist-Løkken I; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology - NTNU, Trondheim, Norway.; Andersson-Rusch C

Subjects: Multiple Myeloma* ; Tacrolimus Binding Protein 1A*/Tacrolimus Binding Protein 1A*/Tacrolimus Binding Protein 1A*/metabolism ; Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/metabolism

Source: Cell communication and signaling : CCS [Cell Commun Signal] 2023 Jan 30; Vol. 21 (1), pp. 25. Date of Electronic Publication: 2023 Jan 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

Molecular Developmental Biology of Fibrodysplasia Ossificans Progressiva: Measuring the Giant by Its Toe.

Authors : Towler OW; Division of Plastic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Shore EM

Subjects: Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/genetics ; Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/metabolism ; Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/pathology

Source: Biomolecules [Biomolecules] 2024 Aug 15; Vol. 14 (8). Date of Electronic Publication: 2024 Aug 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Activin A Modulates Betaglycan Shedding via the ALK4-SMAD3-Dependent Pathway in Endometriotic Cells.

Authors : Mwaura AN; Faculty of Medicine, Center of Gynecology and Obstetrics, Justus-Liebig-University, D-35392 Giessen, Germany.; Riaz MA

Subjects: Activins*/Activins*/Activins*/pharmacology ; Activins*/Activins*/Activins*/metabolism ; Endometriosis*/Endometriosis*/Endometriosis*/metabolism

Source: Biomolecules [Biomolecules] 2022 Nov 24; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.

Authors : Maekawa H; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Subjects: Myositis Ossificans*/Myositis Ossificans*/Myositis Ossificans*/pathology ; Ossification, Heterotopic*/Ossification, Heterotopic*/Ossification, Heterotopic*/genetics ; Ossification, Heterotopic*/Ossification, Heterotopic*/Ossification, Heterotopic*/pathology

Source: Orphanet journal of rare diseases [Orphanet J Rare Dis] 2022 Sep 21; Vol. 17 (1), pp. 364. Date of Electronic Publication: 2022 Sep 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101266602 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1172

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Academic Journal

Cell Senescence in Heterotopic Ossification.

Authors : Pignolo RJ; Department of Medicine, Section of Geriatric Medicine & Gerontology, Mayo Clinic, Rochester, MN 55905, USA.; Divisions of Endocrinology and Hospital Internal Medicine, Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.

Subjects: Ossification, Heterotopic*/Ossification, Heterotopic*/Ossification, Heterotopic*/genetics ; Ossification, Heterotopic*/Ossification, Heterotopic*/Ossification, Heterotopic*/pathology ; Ossification, Heterotopic*/Ossification, Heterotopic*/Ossification, Heterotopic*/metabolism

Source: Biomolecules [Biomolecules] 2024 Apr 16; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Upregulation of oncogene Activin A receptor type I by Helicobacter pylori infection promotes gastric intestinal metaplasia via regulating CDX2.

Authors : Chen HY; Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.; Hu Y

Subjects: Activin Receptors, Type I* ; CDX2 Transcription Factor*/CDX2 Transcription Factor*/CDX2 Transcription Factor*/genetics ; CDX2 Transcription Factor*/CDX2 Transcription Factor*/CDX2 Transcription Factor*/metabolism

Source: Helicobacter [Helicobacter] 2021 Dec; Vol. 26 (6), pp. e12849. Date of Electronic Publication: 2021 Sep 07.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9605411 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma.

Authors : Liu D; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.; Li Z

Subjects: Lymphoma, B-Cell* ; Lymphoma*; Humans

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Mar; Vol. 11 (12), pp. e2306499. Date of Electronic Publication: 2024 Jan 16.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Targeting heterotopic ossification by inhibiting activin receptor‑like kinase 2 function (Review).

Authors : Shi F; Jiangxi Province Key Laboratory of Tumor Pathogens and Molecular Pathology, Department of Pathophysiology, School of Basic Medicine Sciences, Nanchang University Medical College, Nanchang, Jiangxi 330006, P.R. China.; Gao J

Subjects: Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/antagonists & inhibitors ; Activin Receptors, Type I*/Activin Receptors, Type I*/Activin Receptors, Type I*/metabolism ; Drug Delivery Systems*

Source: Molecular medicine reports [Mol Med Rep] 2019 Oct; Vol. 20 (4), pp. 2979-2989. Date of Electronic Publication: 2019 Aug 06.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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فلترة النتائج

Polypeptide Substrate Accessibility Hypothesis: Gain-of-Function R206H Mutation Allosterically Affects Activin Receptor-like Protein Kinase Activity.

AAV-Mediated Targeting of the Activin A-ACVR1 R206H Signaling in Fibrodysplasia Ossificans Progressiva.

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.

Molecular Developmental Biology of Fibrodysplasia Ossificans Progressiva: Measuring the Giant by Its Toe.

Activin A Modulates Betaglycan Shedding via the ALK4-SMAD3-Dependent Pathway in Endometriotic Cells.

Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.

Cell Senescence in Heterotopic Ossification.

Upregulation of oncogene Activin A receptor type I by Helicobacter pylori infection promotes gastric intestinal metaplasia via regulating CDX2.

BMP-ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B-Cell Lymphoma.

Targeting heterotopic ossification by inhibiting activin receptor‑like kinase 2 function (Review).

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