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  • 1-10 ل  63,168 نتائج ل ""AMYOTROPHIC lateral sclerosis""

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Amyotrophic lateral sclerosis.
Research Starter

Amyotrophic lateral sclerosis.

  • DEFINITION: A progressive, degenerative neurological disorder that affects the cells in the brain and spinal cord....More
  • Salem Press Encyclopedia of Health, 2024. 3p.
Academic Journal

Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment.

  • Authors : Liu Q; Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College (PUMC) and Chinese Academy of Medical Science (CAMS), Beijing, China. .; Sun Y

Subjects: Autophagy*/Autophagy*/Autophagy*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 Jan 04; Vol. 13 (1), pp. 2. Date of Electronic Publication: 2025 Jan 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Genetic epidemiology of amyotrophic lateral sclerosis in Cyprus: a population-based study.

  • Authors : Mitsi E; Neurogenetics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.; Neuroepidemiology Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/epidemiology ; C9orf72 Protein*/C9orf72 Protein*/C9orf72 Protein*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Dec 28; Vol. 14 (1), pp. 30781. Date of Electronic Publication: 2024 Dec 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Th17 and effector CD8 T cells relate to disease progression in amyotrophic lateral sclerosis: a case control study.

  • Authors : Itou T; Oncology Drug Discovery Unit Japan, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.; Fujita K

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/immunology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; Disease Progression*

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Dec 27; Vol. 21 (1), pp. 331. Date of Electronic Publication: 2024 Dec 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in an AAV-C9ORF72 (G 4 C 2 ) 66 mouse model.

  • Authors : Thompson EG; Brain Science Institute, Johns Hopkins University School of Medicine, Johns Hopkins University, 855 N. Wolfe St., Rangos 275, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/metabolism

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Dec 26; Vol. 12 (1), pp. 203. Date of Electronic Publication: 2024 Dec 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Artificial Intelligence-Assisted Comparative Analysis of the Overlapping Molecular Pathophysiology of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.

  • Authors : Wei Z; Laboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30322, USA.; Iyer MR

Subjects: Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/genetics ; Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/metabolism ; Frontotemporal Dementia*/Frontotemporal Dementia*/Frontotemporal Dementia*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 15; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis.

  • Authors : Ko VI; Neuroscience Graduate Program, University of California, 9500 Gilman Drive, San Diego, La Jolla, CA, 92093-0624, USA.; Department of Neurosciences, University of California, 9500 Gilman Drive, San Diego, La Jolla, CA, 92093-0624, USA.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/metabolism ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Dec 04; Vol. 12 (1), pp. 187. Date of Electronic Publication: 2024 Dec 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats.

  • Authors : Kim KM; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Girdhar A

Subjects: C9orf72 Protein*/C9orf72 Protein*/C9orf72 Protein*/metabolism ; C9orf72 Protein*/C9orf72 Protein*/C9orf72 Protein*/genetics ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/metabolism

  • Source: Communications biology [Commun Biol] 2025 Jan 02; Vol. 8 (1), pp. 2. Date of Electronic Publication: 2025 Jan 02.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mendelian randomization study supports relative carbohydrate intake as an independent risk factor for amyotrophic lateral sclerosis.

  • Authors : Zeng Y; Department of Anesthesiology, Third Xiangya Hospital, Central South University, Changsha, People's Republic of China.; Guo R

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics ; Mendelian Randomization Analysis* ; Dietary Carbohydrates*/Dietary Carbohydrates*/Dietary Carbohydrates*/administration & dosage

  • Source: Nutritional neuroscience [Nutr Neurosci] 2025 Jan; Vol. 28 (1), pp. 116-124. Date of Electronic Publication: 2024 May 23.Publisher: Taylor & Francis Country of Publication: England NLM ID: 100892202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Deciphering the interactome of Ataxin-2 and TDP-43 in iPSC-derived neurons for potential ALS targets.

  • Authors : Tian Y; Neuroscience, Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey, United States of America.; Heinsinger N

Subjects: Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/metabolism ; Ataxin-2*/Ataxin-2*/Ataxin-2*/metabolism ; Ataxin-2*/Ataxin-2*/Ataxin-2*/genetics

  • Source: PloS one [PLoS One] 2024 Dec 31; Vol. 19 (12), pp. e0308428. Date of Electronic Publication: 2024 Dec 31 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.

  • Authors : Garcia-Toscano L; Geriatrics Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States of America.; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington, United States of America.

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/metabolism ; Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/genetics

  • Source: PLoS genetics [PLoS Genet] 2024 Dec 26; Vol. 20 (12), pp. e1011518. Date of Electronic Publication: 2024 Dec 26 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 ل  63,168 نتائج ل ""AMYOTROPHIC lateral sclerosis""