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  • 1-10 ل  9,680 نتائج ل ""AMYLOID beta-protein precursor""

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Academic Journal

Plasma lipidomics in early APP/PS1 female mouse model and its relationship with brain: Is it affected by the estrous cycle?

  • Authors : Ferré-González L; Alzheimer's Disease Research Group, Instituto de Investigación Sanitaria La Fe, Avda de Fernando Abril Martorell, 106; 46026, Valencia, Spain.

Subjects: Estrous Cycle*/Estrous Cycle*/Estrous Cycle*/physiology ; Estrous Cycle*/Estrous Cycle*/Estrous Cycle*/blood ; Lipidomics*/Lipidomics*/Lipidomics*/methods

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Aug 14; Vol. 16 (1), pp. 183. Date of Electronic Publication: 2024 Aug 14.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.

  • Authors : Honda K; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.; Advanced Prevention and Research Laboratory for Dementia, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.

Subjects: Aging*/Aging*/Aging*/metabolism ; Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism ; Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Aug 09; Vol. 14 (1), pp. 18471. Date of Electronic Publication: 2024 Aug 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Kismet/CHD7/CHD8 and Amyloid Precursor Protein-like Regulate Synaptic Levels of Rab11 at the Drosophila Neuromuscular Junction.

  • Authors : Hendricks EL; Department of Biological Sciences, Southern Illinois University Edwardsville, Edwardsville, IL 62026, USA.; Linskey N

Subjects: Neuromuscular Junction*/Neuromuscular Junction*/Neuromuscular Junction*/metabolism ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 01; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Alpha-lipoic acid alleviates cognitive deficits in transgenic APP23/PS45 mice through a mitophagy-mediated increase in ADAM10 α-secretase cleavage of APP.

  • Authors : Zhang J; Chongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.; Jiang Y

Subjects: Thioctic Acid*/Thioctic Acid*/Thioctic Acid*/pharmacology ; Mice, Transgenic* ; Mitophagy*/Mitophagy*/Mitophagy*/drug effects

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Jul 19; Vol. 16 (1), pp. 160. Date of Electronic Publication: 2024 Jul 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Amelioration of Serum Aβ Levels and Cognitive Impairment in APPPS1 Transgenic Mice Following Symbiotic Administration.

Subjects: *BLOOD serum analysis; *BRAIN physiology; *ALZHEIMER'S disease prevention

  • Source: Nutrients. Aug2024, Vol. 16 Issue 15, p2381. 21p.

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Academic Journal

Serum Beta-Secretase 1 Activity Is a Potential Marker for the Differential Diagnosis between Alzheimer's Disease and Frontotemporal Dementia: A Pilot Study.

Subjects: *ALZHEIMER'S disease; *AMYLOID beta-protein precursor; *FRONTOTEMPORAL dementia

  • Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8354. 12p.

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Academic Journal

Synthesis and Evaluation of Chloride-Substituted Ramalin Derivatives for Alzheimer's Disease Treatment.

Subjects: *AMYLOID beta-protein precursor; *ALZHEIMER'S disease; *NEURODEGENERATION

  • Source: Molecules. Aug2024, Vol. 29 Issue 15, p3701. 16p.

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Academic Journal

Therapeutic potential of APP antisense oligonucleotides for Alzheimer's disease and down syndrome-related Alzheimer's disease.

  • Authors : Thirumalai S; UCL Great Ormond Street Institute of Child Health, Zayed Centre for Research into Rare Disease in Children, 20 Guilford Street, London, WC1N 1DZ, UK.; Patani R

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Down Syndrome*/Down Syndrome*/Down Syndrome*/genetics ; Oligonucleotides, Antisense*/Oligonucleotides, Antisense*/Oligonucleotides, Antisense*/therapeutic use

  • Source: Molecular neurodegeneration [Mol Neurodegener] 2024 Jul 29; Vol. 19 (1), pp. 57. Date of Electronic Publication: 2024 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Academic Journal

Caloric restriction leading to attenuation of experimental Alzheimer's disease results from alterations in gut microbiome.

  • Authors : Chen J; Department of Neurology, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.; Zou C

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/physiology ; Caloric Restriction*/Caloric Restriction*/Caloric Restriction*/methods ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/microbiology

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Jul; Vol. 30 (7), pp. e14823.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Molecular mechanism of substrate recognition and cleavage by human γ-secretase.

  • Authors : Guo X; Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, Key Laboratory for Protein Sciences of Ministry of Education, School of Life Sciences, Tsinghua University, Beijing 100084, China.; Li H

Subjects: Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/chemistry ; Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/chemistry ; Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/Amyloid Precursor Protein Secretases*/chemistry

  • Source: Science (New York, N.Y.) [Science] 2024 Jun 07; Vol. 384 (6700), pp. 1091-1095. Date of Electronic Publication: 2024 Jun 06.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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  • 1-10 ل  9,680 نتائج ل ""AMYLOID beta-protein precursor""