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25. The Role of Alpha-Synuclein (α-syn) Phosphorylation at Ser-129 on the Development of Parkinson-Like Neurodegeneration

• Source: Molecular Therapy ; volume 15, page S11 ; ISSN 1525-0016

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Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

• Authors : Alberto Siddu; Linda Suzanne David; Nadine Lauinger

Subjects: Thy1-α-Syn mice; Cystamine; Neurodegenerative diseases

• Source: Neurobiology of Disease, Vol 145, Iss , Pp 105042- (2020)

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C2 神经酰胺对帕金森病模型鼠多巴胺能神经元的保护作用.

• Authors : 李家慧¹; 齐 雪¹; 朱远峰¹

• Source: Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu. 4/18/2024, Vol. 28 Issue 11, p1653-1659. 7p.

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Parkin depletion delays motor decline dose-dependently without overtly affecting neuropathology in alpha-synuclein transgenic mice.

• Authors : Fournier, Margot; Roux, Amandine; Garrigue, Jérôme ...

Subjects: α-syn phosphorylation; α-syn truncation; Ubiquitin

• Source: ISSN: 1471-2202.

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Parkin depletion delays motor decline dose-dependently without overtly affecting neuropathology in α-synuclein transgenic mice

• Authors : Fournier, Margot; Roux, Amandine; Garrigue, Jérôme

Subjects: α-syn phosphorylation; α-syn truncation; Ubiquitin

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Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.

• Authors : Brembati, Viviana¹ (AUTHOR) ; Faustini, Gaia¹ (AUTHOR) ; Longhena, Francesca¹ (AUTHOR)

Subjects: *POST-translational modification; *PARKINSON'S disease; *ALPHA-synuclein

• Source: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 17, p13435. 19p.

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Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity.

• Authors : Wang, Peng^1,2; Li, Xin¹; Li, Xuran¹

• Source: Parkinson's Disease (20420080). 11/14/2016, p1-14. 14p.

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S-nitrosylation of XIAP impairs its anti-apoptotic function and S-nitrosylation of CK2 regulates its kinase activity and their roles in Parkinson's disease

• Authors : Wu, Weiwei LIFS

Subjects: Protein kinase CK2; Cyclin-dependent kinases; Parkinson's disease

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α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

• Authors : Ghanem, Simona S.; Majbour, Nour K.; Vaikath, Nishant N.

Subjects: Parkinson’s disease; phosphorylation; α-synuclein

• Source: Ghanem , S S , Majbour , N K , Vaikath , N N , Ardah , M T , Erskine , D , Jensen , N M , Fayyad , M , Sudhakaran , I P , Vasili , E , Melachroinou , K , Abdi , I Y , Poggiolini , I , Santos , P ,

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Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model

• Authors : Gustavo Morrone Parfitt; Elena Coccia; Camille Goldman

Subjects: Science

• Source: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

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