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  • 1-25 ل  30,020 نتائج ل ""high-throughput nucleotide sequencing""

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Academic Journal

Assay-guided treatment sequencing in chronic lymphocytic leukemia (CLL): a cost-effectiveness analysis.

  • Authors : Pollard S; Cancer Control Research, BC Cancer, Vancouver, Canada.; Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.

Subjects: Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/economics ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Jul 27; Vol. 14 (1), pp. 17294. Date of Electronic Publication: 2024 Jul 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Implementation, Evolution, and Laboratory Performance of Methods-Based Proficiency Testing for Next-Generation Sequencing Detection of Germline Sequence Variants.

  • Authors : Tsuchiya KD; From the Department of Laboratory Medicine and Pathology, University of Washington, Seattle (Tsuchiya).; Funke B

Subjects: Laboratory Proficiency Testing* ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/standards ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods

  • Source: Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Jul 01; Vol. 148 (7), pp. 775-783.Publisher: College of American Pathologists Country of Publication: United States NLM ID: 7607091 Publication Model: Print Cited Medium: Internet

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Academic Journal

Diagnosis with Metagenomic Next-Generation Sequencing (mNGS) technology and real-time PCR for SARS-CoV-2 Omicron detection using various nasopharyngeal swabs in SARS-CoV-2 Omicron.

  • Authors : Li S; Department of Clinical Laboratory, Hangzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Zhang Y

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/isolation & purification ; COVID-19*/COVID-19*/COVID-19*/diagnosis SARS-CoV-2 variants

  • Source: PloS one [PLoS One] 2024 Aug 06; Vol. 19 (8), pp. e0305289. Date of Electronic Publication: 2024 Aug 06 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

High-throughput single-molecule long-read RNA sequencing analysis of tissue-specific genes and isoforms in lettuce (Lactuca sativa L.).

  • Authors : Shi ZX; Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.; BGI Genomics, BGI-Shenzhen, Shenzhen, China.

Subjects: Lactuca*/Lactuca*/Lactuca*/genetics ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Sequence Analysis, RNA*/Sequence Analysis, RNA*/Sequence Analysis, RNA*/methods

  • Source: Communications biology [Commun Biol] 2024 Jul 31; Vol. 7 (1), pp. 920. Date of Electronic Publication: 2024 Jul 31.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

guidedNOMe-seq quantifies chromatin states at single allele resolution for hundreds of custom regions in parallel.

  • Authors : Schwaiger M; Friedrich Miescher Institute for Biomedical Research, Basel, 4056, Switzerland.; Swiss Institute of Bioinformatics, Basel, 4056, Switzerland.

Subjects: Chromatin*/Chromatin*/Chromatin*/genetics ; Chromatin*/Chromatin*/Chromatin*/metabolism ; Alleles*

  • Source: BMC genomics [BMC Genomics] 2024 Jul 29; Vol. 25 (1), pp. 732. Date of Electronic Publication: 2024 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Automation of customizable library preparation for next-generation sequencing into an open microfluidic platform.

  • Authors : Hoffmann A; Institute of Interfacial Process Engineering and Plasma Technology, University of Stuttgart, Nobelstraße 12, 70569, Stuttgart, Germany.; Corporate Sector Research and Advance Engineering, Robert Bosch GmbH, Robert-Bosch-Campus 1, 71272, Renningen, Germany.

Subjects: High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Gene Library*; Humans

  • Source: Scientific reports [Sci Rep] 2024 Jul 26; Vol. 14 (1), pp. 17150. Date of Electronic Publication: 2024 Jul 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Distribution of EGFR fusions in 35,023 Chinese patients with solid tumors-the frequency, fusion partners and clinical outcome.

  • Authors : Zhang H; Department of Thoracic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.; Wang J

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; Oncogene Proteins, Fusion*/Oncogene Proteins, Fusion*/Oncogene Proteins, Fusion*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: World journal of surgical oncology [World J Surg Oncol] 2024 Jul 25; Vol. 22 (1), pp. 194. Date of Electronic Publication: 2024 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819

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Academic Journal

Investigation of acute encephalitis syndrome with implementation of metagenomic next generation sequencing in Nepal.

  • Authors : Rajeev S; Center for Infectious Disease Research and Surveillance, Dhulikhel Hospital Kathmandu University Hospital, Dhulikhel, Nepal. .; Department of Pharmacology, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal. .

Subjects: Metagenomics*/Metagenomics*/Metagenomics*/methods ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Acute Febrile Encephalopathy*/Acute Febrile Encephalopathy*/Acute Febrile Encephalopathy*/epidemiology

  • Source: BMC infectious diseases [BMC Infect Dis] 2024 Jul 25; Vol. 24 (1), pp. 734. Date of Electronic Publication: 2024 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334

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Academic Journal

Clinical application and evaluation of metagenomic next-generation sequencing in pathogen detection for suspected central nervous system infections.

  • Authors : Yuan L; Department of Clinical Laboratory, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People's Republic of China.; Zhu XY

Subjects: High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Central Nervous System Infections*/Central Nervous System Infections*/Central Nervous System Infections*/diagnosis ; Central Nervous System Infections*/Central Nervous System Infections*/Central Nervous System Infections*/microbiology

  • Source: Scientific reports [Sci Rep] 2024 Jul 23; Vol. 14 (1), pp. 16961. Date of Electronic Publication: 2024 Jul 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Detection Ewingella americana from a patient with Andersson lesion in ankylosing spondylitis by metagenomic next-generation sequencing test: a case report.

  • Authors : Wu H; Department of Orthopedic Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, China.; Wu X

Subjects: Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/diagnosis ; Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/complications ; Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/Spondylitis, Ankylosing*/microbiology

  • Source: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Jul 20; Vol. 25 (1), pp. 568. Date of Electronic Publication: 2024 Jul 20.Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474

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Academic Journal

The Advantage of Targeted Next-Generation Sequencing over qPCR in Testing for Druggable EGFR Variants in Non-Small-Cell Lung Cancer.

  • Authors : Szpechcinski A; Department of Genetics and Clinical Immunology, The Institute of Tuberculosis and Lung Diseases, 01-138 Warsaw, Poland.; Moes-Sosnowska J

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 19; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Metagenomic next-generation sequencing for the diagnosis of invasive pulmonary aspergillosis in type 2 diabetes mellitus patients.

  • Authors : Liu Z; Department of Clinical Laboratory, Huizhou Central People's Hospital, Huizhou, 516001, Guangdong, China.; Chen H

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/complications ; Invasive Pulmonary Aspergillosis*/Invasive Pulmonary Aspergillosis*/Invasive Pulmonary Aspergillosis*/diagnosis ; Invasive Pulmonary Aspergillosis*/Invasive Pulmonary Aspergillosis*/Invasive Pulmonary Aspergillosis*/microbiology

  • Source: Scientific reports [Sci Rep] 2024 Jul 18; Vol. 14 (1), pp. 16618. Date of Electronic Publication: 2024 Jul 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Characterization of Six Ampeloviruses Infecting Pineapple in Reunion Island Using a Combination of High-Throughput Sequencing Approaches.

  • Authors : Massé D; ANSES-LSV RAPT, F-97410 St. Pierre, La Réunion, France.; UMR PVBMT, Université de La Réunion, F-97410 St. Pierre, La Réunion, France.

Subjects: Ananas*/Ananas*/Ananas*/virology ; High-Throughput Nucleotide Sequencing* ; Genome, Viral*

  • Source: Viruses [Viruses] 2024 Jul 16; Vol. 16 (7). Date of Electronic Publication: 2024 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Integrating the Idylla™ System Alongside a Real-Time Polymerase Chain Reaction and Next-Generation Sequencing for Investigating Gene Fusions in Pleural Effusions from Non-Small-Cell Lung Cancer Patients: A Pilot Study.

  • Authors : Scarpino S; Department of Clinical and Molecular Medicine, Morphologic and Molecular Pathology Unit, St. Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy.; Leone A

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 11; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The polygenic implication of clopidogrel responsiveness: Insights from platelet reactivity analysis and next-generation sequencing.

  • Authors : Echeverría O; School of Medicine and Health Sciences, Center for Research in Genetics and Genomics (CIGGUR), Institute of Translational Medicine (IMT), Universidad Del Rosario, Bogotá D.C., Colombia.; Angulo-Aguado M

Subjects: Clopidogrel*/Clopidogrel*/Clopidogrel*/therapeutic use ; Clopidogrel*/Clopidogrel*/Clopidogrel*/pharmacology ; Polymorphism, Single Nucleotide*

  • Source: PloS one [PLoS One] 2024 Jul 11; Vol. 19 (7), pp. e0306445. Date of Electronic Publication: 2024 Jul 11 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

ProcaryaSV: structural variation detection pipeline for bacterial genomes using short-read sequencing.

  • Authors : Jugas R; Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic.; Vitkova H

Subjects: Genome, Bacterial* ; Software* ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods

  • Source: BMC bioinformatics [BMC Bioinformatics] 2024 Jul 09; Vol. 25 (1), pp. 233. Date of Electronic Publication: 2024 Jul 09.Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105

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Academic Journal

Rapid diagnosis of alveolar echinococcosis from lung puncture sample using metagenomic next-generation sequencing: a case report.

  • Authors : Zhou C; Ward of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.; Li C

Subjects: High-Throughput Nucleotide Sequencing* ; Lung*/Lung*/Lung*/parasitology ; Lung*/Lung*/Lung*/pathology Alveolar echinococcosis

  • Source: BMC infectious diseases [BMC Infect Dis] 2024 Jul 09; Vol. 24 (1), pp. 683. Date of Electronic Publication: 2024 Jul 09.Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334

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Academic Journal

Cell free DNA in patients with pancreatic adenocarcinoma: clinicopathologic correlations.

  • Authors : Theparee T; Department of Pathology and Laboratory Medicine, NorthShore University Health System, Evanston, IL, USA.; Department of Pathology, Chulalongkorn University Faculty of Medicine, Bangkok, Thailand.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/blood

  • Source: Scientific reports [Sci Rep] 2024 Jul 08; Vol. 14 (1), pp. 15744. Date of Electronic Publication: 2024 Jul 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort.

  • Authors : Chaudhary P; Molecular Department, Unipath Specialty Laboratory Ltd, Ahmedabad, Gujarat, India. .; Chaudhary S

Subjects: Fusion Proteins, bcr-abl*/Fusion Proteins, bcr-abl*/Fusion Proteins, bcr-abl*/genetics ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Jul 08; Vol. 14 (1), pp. 15745. Date of Electronic Publication: 2024 Jul 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Unraveling the lncRNA-miRNA-mRNA Regulatory Network Involved in Poplar Coma Development through High-Throughput Sequencing.

  • Authors : Song Z; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China.; Zhang C

Subjects: Populus*/Populus*/Populus*/genetics ; RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics ; Gene Regulatory Networks*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 05; Vol. 25 (13). Date of Electronic Publication: 2024 Jul 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua).

  • Authors : Györkei Á; Department of Biosciences, Section for Physiology and Cell Biology, University of Oslo, Oslo, Norway.; Johansen FE

Subjects: Gadus morhua*/Gadus morhua*/Gadus morhua*/genetics ; High-Throughput Nucleotide Sequencing*; Animals

  • Source: BMC genomics [BMC Genomics] 2024 Jul 03; Vol. 25 (1), pp. 663. Date of Electronic Publication: 2024 Jul 03.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Low-Input, High-Resolution 5' Terminal Filovirus RNA Sequencing with ViBE-Seq.

  • Authors : Ross SJ; Department of Virology, Immunology & Microbiology, Chobanian and Avedisian School of Medicine, Boston University, Boston, MA 02215, USA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02215, USA.

Subjects: RNA, Viral*/RNA, Viral*/RNA, Viral*/genetics ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Genome, Viral*

  • Source: Viruses [Viruses] 2024 Jul 01; Vol. 16 (7). Date of Electronic Publication: 2024 Jul 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Targeted next-generation sequencing reveals the genetic mechanism of Chinese Marfan syndrome cohort with ocular manifestation.

  • Authors : Han D; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.; Wang Z

Subjects: Marfan Syndrome*/Marfan Syndrome*/Marfan Syndrome*/genetics ; Marfan Syndrome*/Marfan Syndrome*/Marfan Syndrome*/pathology ; Fibrillin-1*/Fibrillin-1*/Fibrillin-1*/genetics

  • Source: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2024 Jul; Vol. 12 (7), pp. e2482.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101603758 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Astrovirus induced nonpurulent encephalomyelitis in sheep: First report from Türkiye by high-throughput sequencing.

  • Authors : Eroksuz Y; Department of Pathology, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey.; Timurkan MO

Subjects: Astroviridae Infections*/Astroviridae Infections*/Astroviridae Infections*/veterinary ; Astroviridae Infections*/Astroviridae Infections*/Astroviridae Infections*/virology ; Sheep Diseases*/Sheep Diseases*/Sheep Diseases*/virology

  • Source: Veterinary medicine and science [Vet Med Sci] 2024 Jul; Vol. 10 (4), pp. e1499.Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101678837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Back-to-Back Comparison of Third-Generation Sequencing and Next-Generation Sequencing in Carrier Screening of Thalassemia.

  • Authors : Huang R; From the Department of Genetics and Prenatal Diagnosis, Hainan Women and Children's Medical Center, Haikou, 571100, China (Huang, J. Xu, Lin, Yang, Zhong, Wang, Zhou).; Liu Y

Subjects: High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods ; Thalassemia*/Thalassemia*/Thalassemia*/genetics ; Thalassemia*/Thalassemia*/Thalassemia*/diagnosis

  • Source: Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Jul 01; Vol. 148 (7), pp. 797-804.Publisher: College of American Pathologists Country of Publication: United States NLM ID: 7607091 Publication Model: Print Cited Medium: Internet

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  • 1-25 ل  30,020 نتائج ل ""high-throughput nucleotide sequencing""