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Health educators' professional agency in negotiating their Problem-Based Learning (PBL) facilitator roles: Q study

• Authors : Du, Xiangyun; Nomikos, Michail; Ali, Kamran

• Source: Medical Education. 56(8):847-857

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Biochemical and structural impact of two novel missense mutations in cystathionine γ-synthase gene associated with homocystinuria.

• Authors : Al-Sadeq, Duaa W.^1,2; Conter, Carolina^3,4; Thanassoulas, Angelos¹

Subjects: *MISSENSE mutation; *CYSTATHIONINE; *PROTEIN stability

• Source: Biochemical Journal. Apr2024, Vol. 481 Issue 8, p569-585. 17p.

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Divergent biochemical properties and disparate impact of arrhythmogenic calmodulin mutations on zebrafish cardiac function

• Authors : Da'as, Sahar I.; Thanassoulas, Angelos; Calver, Brian L.

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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria

• Authors : Al-Sadeq, Duaa W.; Conter, Carolina; Thanassoulas, Angelos ...

• Source: Biochemical Journal ; volume 481, issue 8, page 569-585 ; ISSN 0264-6021 1470-8728

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The mammalian sperm factor phospholipase C zeta is critical for early embryo division and pregnancy in humans and mice

• Authors : Kashir, Junaid; Mistry, Bhavesh V; Rajab, Mohamed A ...

• Source: Human Reproduction ; volume 39, issue 6, page 1256-1274 ; ISSN 0268-1161 1460-2350

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Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket.

• Authors : Thanassoulas, Angelos¹ (AUTHOR) ; Theodoridou, Maria² (AUTHOR) ; Barrak, Laila¹ (AUTHOR)

Subjects: *CALMODULIN; *RYANODINE receptors; *MUTANT proteins

• Source: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 21, p15630. 14p.

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Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket

• Authors : Thanassoulas, Angelos; Vassilakopoulou, Vyronia; Calver, Brian L.

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Editorial: The role of calcium signaling in gametogenesis and early embryogenesis

• Authors : Kashir, Junaid; Lai, F. Anthony; Nomikos, Michail

• Source: Frontiers in Cell and Developmental Biology ; volume 10 ; ISSN 2296-634X

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Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype

• Authors : Al-Sadeq, Duaa W.; Thanassoulas, Angelos; Islam, Zeyaul ...

• Source: Biochimica et Biophysica Acta (BBA) - General Subjects ; volume 1866, issue 7, page 130148 ; ISSN 0304-4165

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BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer.

• Authors : Ismail, Tala; Alzneika, Safa; Riguene, Emna

Subjects: BREAST; BRCA genes; OVARIAN cancer

• Source: Pharmaceuticals (14248247); Mar2024, Vol. 17 Issue 3, p333, 16p

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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model.

• Authors : Da'as, Sahar Isa^1,2 (AUTHOR) ; Hasan, Waseem¹ (AUTHOR); Salem, Rola³ (AUTHOR)

Subjects: *HYPERTROPHIC cardiomyopathy; *CARRIER proteins; *BRACHYDANIO

• Source: International Journal of Molecular Sciences. Aug2022, Vol. 23 Issue 16, p8840-N.PAG. 20p.

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Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains

• Authors : Kashir, Junaid; Mistry, Bhavesh V; Gumssani, Maha Adel

• Source: Asian Journal of Andrology ; volume 23, issue 2, page 178-187 ; ISSN 1008-682X

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Medical Students’ Perspectives on an Assessment of Reflective Portfolios [Response to Letter]

• Authors : Kassab,Salah Eldin; Bidmos,Mubarak; Nomikos,Michail

Subjects: Advances in Medical Education and Practice

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Construct Validity of an Instrument for Assessment of Reflective Writing-Based Portfolios of Medical Students

• Authors : Kassab,Salah Eldin; Bidmos,Mubarak; Nomikos,Michail

Subjects: Advances in Medical Education and Practice

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Construct validity of an instrument for assessment of reflective writing-based portfolios of medical students

• Authors : Kassab, Salah Eldin; Bidmos, Mubarak; Nomikos, Michail

Subjects: G-theory; Portfolio; Reflective writing

• Source: Kassab , S E , Bidmos , M , Nomikos , M , Daher-Nashif , S , Kane , T , Sarangi , S & Abu-Hijleh , M 2020 , ' Construct validity of an instrument for assessment of

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Medical students’ perspectives on an assessment of reflective portfolios [response to letter]

• Authors : Kassab, Salah Eldin; Bidmos, Mubarak; Nomikos, Michail

• Source: Kassab , S E , Bidmos , M , Nomikos , M , Daher-Nashif , S , Kane , T , Sarangi , S & Abu-Hijleh , M 2020 , ' Medical students’ perspectives on an assessment of

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Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update

• Authors : Saleh, Alaaeldin; Kashir, Junaid; Thanassoulas, Angelos ...

• Source: Frontiers in Cell and Developmental Biology ; volume 8 ; ISSN 2296-634X

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Defective Interaction of Cam with RyR2 Cam-Binding Pocket Might Contribute to Arrhythmogenic Cardiac Disease

• Authors : Nomikos, Michail; Thanassoulas, Angelos; Vassilakopoulou, Vyronia

• Source: Biophysical Journal ; volume 118, issue 3, page 565a ; ISSN 0006-3495

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The Arrhythmogenic E105A CAM Mutation Dysregulates Normal Cardiac Function in Zebrafish by Altering CAM-Ca2+ and CAM-RyR2 Interactions

• Authors : Nomikos, Michail; Da’as, Sahar I.; Thanassoulas, Angelos

• Source: Biophysical Journal ; volume 116, issue 3, page 240a ; ISSN 0006-3495

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Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes.

• Authors : Burgon, Patrick G.; Weldrick, Jonathan J.; Talab, Omar Mohamed Sayed Ahmed

Subjects: HEART failure; MYOCARDIAL infarction; HEART development

• Source: Cells (2073-4409); Sep2023, Vol. 12 Issue 18, p2324, 21p

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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics

• Authors : Nomikos, Michail; Thanassoulas, Angelos; Calver, Brian L.

• Source: Biophysical Journal ; volume 114, issue 3, page 467a ; ISSN 0006-3495

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Calmodulin Interacts and Regulates Enzyme Activity of the Mammalian Sperm Phospholipase C

• Authors : Nomikos, Michail; Thanassoulas, Angelos; Calver, Brian L.

• Source: Biophysical Journal ; volume 112, issue 3, page 398a-399a ; ISSN 0006-3495

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Ca2+ dynamics in oocytes from naturally-aged mice

• Authors : Haverfield, Jenna; Nakagawa, Shoma; Love, Daniel

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Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function

• Authors : Nomikos, Michail; Thanassoulas, Angelos; Beck, Konrad ...

• Source: The FEBS Journal ; volume 283, issue 24, page 4502-4514 ; ISSN 1742-464X 1742-4658

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Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction.

• Authors : Da'as, Sahar I.^1,2; Fakhro, Khalid^1,2,3; Thanassoulas, Angelos⁴

Subjects: *HYPERTROPHIC cardiomyopathy; *MYOSIN; *GENETIC mutation

• Source: Biochemical Journal. 12/21/2018, Vol. 475 Issue 24, p3933-3948. 16p.

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