نتائج البحث

In silico modeling and simulation of organ‐on‐a‐chip systems to support data analysis and a priori experimental design

• Authors : Nicoló Milani; Neil Parrott; Aleksandra Galetin

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 4, Pp 524-543 (2024)

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Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL‐6 levels following administration of the T‐cell bispecific engager glofitamab

• Authors : Nassim Djebli; Neil Parrott; Felix Jaminion

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 396-409 (2024)

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Development and application of neonatal physiology‐based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment

• Authors : Christopher A. Darlow; Neil Parrott; Richard W. Peck

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 464-475 (2024)

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Introduction of an artificial neural network–based method for concentration‐time predictions

• Authors : Dominic Stefan Bräm; Neil Parrott; Lucy Hutchinson

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 6, Pp 745-754 (2022)

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Correction: Van der Veken et al. Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study. Pharmaceutics 2022, 14, 1935

• Authors : Matthias Van der Veken; Michael Aertsen; Joachim Brouwers

Subjects: n/a; Pharmacy and materia medica; RS1-441

• Source: Pharmaceutics, Vol 15, Iss 9, p 2323 (2023)

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Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A Retrospective Case Study of the Utility for Formulation Bridging

• Authors : Tejashree Belubbi; Davide Bassani; Cordula Stillhart

Subjects: food effect; oral absorption; PBBM

• Source: Pharmaceutics; Volume 15; Issue 1; Pages: 191

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A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist

• Authors : Caroline Rynn (1541881); Kenichi Umehara (13293918); Tianyi Jiang (166672)

Subjects: Biochemistry; Medicine; Microbiology

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Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study

• Authors : Matthias Van der Veken; Michael Aertsen; Joachim Brouwers

Subjects: MRI; biorelevant dissolution; PBPK

• Source: Pharmaceutics; Volume 14; Issue 9; Pages: 1935

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Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

• Authors : Yuan Chen; Tamara D. Cabalu; Ernesto Callegari

Subjects: Therapeutics. Pharmacology; RM1-950

• Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 9, Pp 685-695 (2019)

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PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5′-Diphospho-glucuronosyltransferase Substrates

• Authors : Micaela B. Reddy; Michael B. Bolger; Grace Fraczkiewicz

Subjects: GastroPlus; PBPK; UGT

• Source: Pharmaceutics; Volume 13; Issue 9; Pages: 1325

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Safety Testing of an Antisense Oligonucleotide Intended for Pediatric Indications in the Juvenile Göttingen Minipig, including an Evaluation of the Ontogeny of Key Nucleases

• Authors : Allan Valenzuela; Claire Tardiveau; Miriam Ayuso

Subjects: antisense oligonucleotide (ASO); endonuclease; exonuclease

• Source: Pharmaceutics; Volume 13; Issue 9; Pages: 1442

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Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

• Authors : Lichuan Liu; Tamara D. Cabalu; Stephen D. Hall

Subjects: Physiologically based pharmacokinetic modelling; Itraconazole; Drug-drug interaction

• Source: CPT: Pharmacometrics & Systems PharmacologyCPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 9, Pp 685-695 (2019)

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PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5′-Diphospho-glucuronosyltransferase Substrates

• Authors : Laibin Luo; James M. Mullin; Viera Lukacova

Subjects: PBPK; Physiologically based pharmacokinetic modelling; Glucuronosyltransferase

• Source: Pharmaceutics, Vol 13, Iss 1325, p 1325 (2021)Pharmaceutics

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An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery

• Authors : Philippe Coassolo; Thierry Lavé; Nicolas Paquereau

Subjects: Male; Time Factors; Biological Availability

• Source: Journal of Pharmaceutical Sciences. 94:2327-2343

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Application of Full Physiological Models for Pharmaceutical Drug Candidate Selection and Extrapolation of Pharmacokinetics to Man

• Authors : Hannah M. Jones; Nicolas Paquereau; Thierry Lavé

Subjects: Pharmacology; Pharmaceutical drug; business.industry

• Source: Basic Toxicology. 96:193-199

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Challenges and opportunities with modelling and simulation in drug discovery and drug development

• Authors : Thierry Lavé; A. Fleury; Hans Peter Grimm

Subjects: Schedule; Physiologically based pharmacokinetic modelling; Computer science

• Source: Xenobiotica; the fate of foreign compounds in biological systems. 37(10-11)

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Journal of Pharmacology and Experimental Therapeutics

• Authors : Lothar Lindemann; Georg Jaeschke; Aubin Michalon ...

Subjects: Radioligand binding assays Tracer Conc. Kd Source Reference

• Source: http://jpet.aspetjournals.org/content/suppl/2011/08/17/jpet.111.185660.DC1/JPET185660_revised_supplemental_material.pdf.

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MODELLING AND SIMULATION OF PHARMACOKINETIC AND PHARMACODYNAMIC SYSTEMS- APPROACHES IN DRUG DISCOVERY

• Authors : Alex J. Macdonald; Neil Parrott; Hannah Jones ...

• Source: http://www.beilstein-institut.de/bozen2004/proceedings/MacDonald/MacDonald.pdf.

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Impact of intracellular bioavailability on metabolic drug-drug interactions

• Authors : Treyer, Andrea; Ullah, Mohammed; Neil, Parrott

Subjects: Pharmaceutical Sciences; Farmaceutiska vetenskaper; Manuscript (preprint)

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Petitioning Goes Online.

• Authors : Eslick, Camille

• Source: Campaigns & Elections (2010). Jul/Aug2011, Vol. 32 Issue 305, p48-49. 2p.

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Ship Leaves Little Wake, But Makes Lasting Impression.

• Authors : Gallant, Julie

Subjects: MILITARY transportation; MILITARY sealift; BOATS & boatingUNITED States

• Source: San Diego Business Journal. 6/5/2006, Vol. 27 Issue 23, p1-33. 3p.

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Md. Immigrant Tuition Plan Headed for 2012 Referendum.

• Authors : WITTE, BRIAN

Subjects: UNDOCUMENTED immigrants; TUITION laws; EDUCATIONAL law & legislationMARYLAND

• Source: Community College Week. 7/25/2011, Vol. 23 Issue 25, p5-5. 1/2p.

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Democrat David Trone reelected to US House in Maryland

• Source: AP Regional State Report - Maryland, 11/11/2022

تفاصيل العنوان

Democrat David Trone reelected to US House in Maryland

• Source: US News Online, 11/11/2022

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Trone, Parrott, congressional rematch appears competitive

• Source: AP English Worldstream - English, 11/08/2022

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Trone, Parrott, congressional rematch too early to call

• Source: AP English Worldstream - English, 11/09/2022

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Trone, Parrott, congressional rematch a competitive one

• Source: AP Regional State Report - Maryland, 11/09/2022

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