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Rare germline copy number variants (CNVs) and breast cancer risk

• Authors : Dennis, Joe; Tyrer, Jonathan P; Walker, Logan C

Subjects: Human Genome; Breast Cancer; Genetics

• Source: Communications Biology. 5(1)

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Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women

• Authors : Dorling, Leila; Carvalho, Sara; Allen, Jamie

Subjects: Breast Cancer; Cancer; Genetics

• Source: New England Journal of Medicine. 384(5)

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Cancer risks associated with germline PALB2 pathogenic variants : An international study of 524 families

• Authors : Yang, Xin; Leslie, Goska; Doroszuk, Alicja

Subjects: Medicin och hälsovetenskap; Klinisk medicin; Cancer och onkologi

• Source: Journal of Clinical Oncology. 38(7):674-685

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Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types

• Authors : Naderi, Elnaz; Schack, Line Meinertz Hybel; Dorling, Leila ...

Subjects: Càncer; Radiació; Genomes

• Source: Scientia

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The impact of coding germline variants on contralateral breast cancer risk and survival

• Authors : Morra, Anna; Mavaddat, Nasim; Muranen, Taru A.

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Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls

• Authors : Zanti, Maria; Loizidou, Maria A.; O’Mahony, Denise G.

Subjects: Genetics (clinical); Genetics; Molecular Medicine

• Source: Frontiers in Genetics ; volume 14 ; ISSN 1664-8021

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Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

• Authors : Li, Jingmei; Wen, Wei Xiong; Eklund, Martin

Subjects: BRCA1; BRCA2; breast cancer

• Source: International Journal of Cancer BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 144(5):1195-1204

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Breast cancer risks associated with missense variants in breast cancer susceptibility genes

• Authors : Dorling, Leila;

Subjects: Breast cancer; Genetic epidemiology; Risk prediction

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Segregation analysis of 17,425 population-based breast cancer families: Evidence for genetic susceptibility and risk prediction. ...

• Authors : Li, Shuai; MacInnis, Robert J; Lee, Andrew

Subjects: ATM; BOADICEA; BRCA1

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Breast cancer risks associated with missense variants in breast cancer susceptibility genes

• Authors : NBCS Collaborators; kConFab Investigators; SGBCC Investigators ...

Subjects: Breast cancer; Genetic epidemiology; Risk prediction

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Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

• Authors : Breast Canc Assoc Consortium; Mavaddat, Nasim; Dorling, Leila ...

Subjects: INTERNATIONAL EXPERT CONSENSUS; BRCA2 MUTATION CARRIERS; PRIMARY THERAPY

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Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer

• Authors : Naderi, Elnaz; Schack, Line M.H.; Welsh, Ceilidh

Subjects: Head and neck cancer; Meta-GWAS; Polygenic risk score

• Source: Radiogenomics Consortium , Naderi , E , Schack , L M H , Welsh , C , Sim , A Y L , Aguado-Barrera , M E , Dudding , T , Summersgil , H , Martínez-Calvo , L , Ong , E H W , Odding , Y , Varela-Pazos ,

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A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis

• Authors : Schack, Line M H; Naderi, Elnaz; Fachal, Laura

• Source: Head and Neck Group of the Radiogenomics Consortium , Schack , L M H , Naderi , E , Fachal , L , Dorling , L , Luccarini , C , Dunning , A M , Ong , E H W , Chua , M L K

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Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.

• Authors : Yang, Xin; Eriksson, Mikael; Czene, Kamila

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Splicing predictions, minigene analyses, and ACMG-AMP clinical classification of 42 germline PALB2 splice-site variants.

• Authors : Valenzuela-Palomo, Alberto; Bueno-Martínez, Elena; Sanoguera-Miralles, Lara

Subjects: PALB2; VUS; aberrant splicing

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Rare germline copy number variants (CNVs) and breast cancer risk ; ENEngelskEnglishRare germline copy number variants (CNVs) and breast cancer risk

• Authors : Dennis, Joe; Tyrer, Jonathan P.; Walker, Logan C.

• Source: 2399-3642.

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Pathology of Tumors Associated with Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

• Authors : Mavaddat, Nasim; Dorling, Leila; Carvalho, Sara

• Source: Mavaddat , N , Dorling , L , Carvalho , S , Allen , J , González-Neira , A , Keeman , R , Bolla , M K , Dennis , J , Wang , Q , Ahearn , T U , Andrulis , I L , Beckmann

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Splicing predictions, minigene analyses and ACMG/AMP clinical classification of 42 germline PALB2 splice-site variants

• Authors : Valenzuela-Palomo, Alberto; Bueno-Martínez, Elena; Sanoguera-Miralles, Lara ...

Subjects: Breast cancer; Susceptibility genes; PALB2

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No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity

• Authors : Barnett, Gillian C.; Kerns, Sarah L.; Dorling, Leila

Subjects: Cancer Research; Radiology, Nuclear Medicine and imaging; Oncology

• Source: International Journal of Radiation Oncology*Biology*Physics ; volume 114, issue 3, page 494-501 ; ISSN 0360-3016

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Rare germline copy number variants (CNVs) and breast cancer risk

• Authors : Dennis, Joe; Tyrer, Jonathan; Walker, Logan C

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Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy

• Authors : Kerns, Sarah L; Fachal, Laura; Dorling, Leila ...

• Source: JNCI: Journal of the National Cancer Institute ; volume 112, issue 2, page 179-190 ; ISSN 0027-8874 1460-2105

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Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

• Authors : Li, Jingmei; Wen, Wei Xiong; Eklund, Martin ...

• Source: International Journal of Cancer ; volume 144, issue 5, page 1195-1204 ; ISSN 0020-7136 1097-0215

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Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients

• Authors : Andreassen, Christian Nicolaj; Rosenstein, Barry S; Kerns, Sarah L

Subjects: Alleles; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms

• Source: Andreassen , C N , Rosenstein , B S , Kerns , S L , Ostrer , H , De Ruysscher , D , Cesaretti , J A , Barnett , G C , Dunning , A M , Dorling , L , West , C M L , Burnet

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Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.

• Authors : Ahmed, Mahbubl; Dorling, Leila; Kerns, Sarah

Subjects: Aged; European Continental Ancestry Group; Genetic Predisposition to Disease

• Source: Ahmed , M , Dorling , L , Kerns , S , Fachal , L , Elliott , R , Partliament , M , Rosenstein , B S , Vega , A , Gómez-Caamaño , A , Barnett , G , Dearnaley , D P ,

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Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

• Authors : Kerns, Sarah L; Dorling, Leila; Fachal, Laura

Subjects: ResearchInstitutes_Networks_Beacons/mcrc; Manchester Cancer Research Centre

• Source: Kerns , S L , Dorling , L , Fachal , L , Bentzen , S , Pharoah , P D P , Barnes , D R , Gómez-Caamaño , A , Carballo , A M , Dearnaley , D P , Peleteiro , P ,

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