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HDAC inhibitors Panobinostat and Romidepsin enhance

• Authors : Annika P, Schnell; Stephan, Kohrt; Aris, Aristodemou

Subjects: Histone Deacetylase Inhibitors; Human T-lymphotropic virus 1; Vorinostat

• Source: Frontiers in immunology. 13

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Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

• Authors : Oregon Health and Science University; Lara Davis, MD, Principal Investigator

• Source: Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) Trial: PRIME

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Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

• Authors : Paul Wood; Rodney J. Hicks; Jake Shortt

Subjects: 0301 basic medicine; Regulation of gene expression; Cancer Research

• Source: International Journal of Cancer. 139:194-204

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Phase ia/ii, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies

• Authors : DeAngelo, D J; Spencer, A; Bhalla, K N

Subjects: panobinostat; histone deacetylase; myelofibrosis

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Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines

• Authors : Eva Bernhart; Nicholas Donohue; Heike Kaltenegger

Subjects: 0301 basic medicine; panobinostat; sarcoma

• Source: Oncotarget

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Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb

• Authors : B SiwakEdward; JanYih; JamaluddinMd Saha

Subjects: 0301 basic medicine; CD4-Positive T-Lymphocytes; Gene Expression Regulation, Viral

• Source: AIDS research and human retroviruses. 32(2)

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Role of Histone Deacetylase Inhibitors in Relapsed Refractory Multiple Myeloma: A Focus on Vorinostat and Panobinostat

• Authors : Ola Landgren; Mabel Rodriguez; Salma Afifi

Subjects: Indoles; Antineoplastic Agents; Pharmacology

• Source: Pharmacotherapy. 35(12)

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Phase ia/ii, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies

• Authors : Angela Liu; Daniel J. DeAngelo; Thomas Kindler

Subjects: Male; Oncology; Cancer Research

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Recent developments of HDAC inhibitors: Emerging indications and novel molecules

• Authors : Bondarev, Andrey D; Attwood, Misty M.; Jonsson, Jörgen

Subjects: HDAC inhibition; belinostat; epigenetics

• Source: British Journal of Clinical Pharmacology. 87(12):4577-4597

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Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study

• Authors : Ocio EM; Herrera P; Olave MT

Subjects: II TRIAL; OUTCOMES; CELL TRANSPLANTATION

• Source: HAEMATOLOGICAr-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Feinstname

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