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  • 1-10 ل  6,239 نتائج ل ""DNA damage""

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Subject : tumor suppressor protein p53
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Academic Journal

The molecular characteristics of DNA damage and repair related to P53 mutation for predicting the recurrence and immunotherapy response in hepatocellular carcinoma.

  • Authors : Ma J; Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Tang D

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/therapy ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology

  • Source: Scientific reports [Sci Rep] 2025 Apr 29; Vol. 15 (1), pp. 14939. Date of Electronic Publication: 2025 Apr 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

USP33 Regulates DNA Damage Response and Carcinogenesis Through Deubiquitylating and Stabilising p53.

  • Authors : Zhu Y; China National Center for Bioinformation, Beijing, China.; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; DNA Damage*

  • Source: Cell proliferation [Cell Prolif] 2025 May; Vol. 58 (5), pp. e13793. Date of Electronic Publication: 2024 Dec 18.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Academic Journal

Unraveling the Guardian: p53's Multifaceted Role in the DNA Damage Response and Tumor Treatment Strategies.

  • Authors : Zhang H; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.; Xu J

Subjects: DNA Damage* ; DNA Repair*/DNA Repair*/DNA Repair*/drug effects ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 01; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

DNA Damage and Inflammatory Response of p53 Null H358 Non-Small Cell Lung Cancer Cells to X-Ray Exposure Under Chronic Hypoxia.

  • Authors : Nisar H; Department of Radiation Biology, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51147 Cologne, Germany.; Department of Medical Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Islamabad 44000, Pakistan.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 23; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The levels of p53 govern the hierarchy of DNA damage tolerance pathway usage.

  • Authors : Castaño BA; Department of Obstetrics and Gynecology, Ulm University, Ulm 89075, Germany.; Schorer S

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Apr 24; Vol. 52 (7), pp. 3740-3760.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

YTHDC1 m 6 A-dependent and m 6 A-independent functions converge to preserve the DNA damage response.

  • Authors : Elvira-Blázquez D; Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.; Institute of Health Research of Navarra (IdiSNA), Pamplona, Spain.

Subjects: DNA Damage* ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics

  • Source: The EMBO journal [EMBO J] 2024 Aug; Vol. 43 (16), pp. 3494-3522. Date of Electronic Publication: 2024 Jul 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-Damage-Sensing-Dependent Cell Protection.

  • Authors : Centeno D; Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ 07030, USA.; Farsinejad S

Subjects: Taurine*/Taurine*/Taurine*/pharmacology ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

  • Source: Nutrients [Nutrients] 2024 Jun 09; Vol. 16 (12). Date of Electronic Publication: 2024 Jun 09.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

miR-34a is a tumor suppressor in zebrafish and its expression levels impact metabolism, hematopoiesis and DNA damage.

  • Authors : Prykhozhij SV; Children's Hospital of Eastern Ontario (CHEO) Research Institute and University of Ottawa, Ottawa, Ontario, Canada.; Ban K

Subjects: DNA Damage* ; Hematopoiesis*/Hematopoiesis*/Hematopoiesis*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: PLoS genetics [PLoS Genet] 2024 May 28; Vol. 20 (5), pp. e1011290. Date of Electronic Publication: 2024 May 28 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

DNA damage induces p53-independent apoptosis through ribosome stalling.

  • Authors : Boon NJ; Oncode Institute, Utrecht, Netherlands.; Division of Biochemistry, Netherlands Cancer Institute, Amsterdam, Netherlands.

Subjects: Apoptosis* ; DNA Damage* ; Protein Biosynthesis*

  • Source: Science (New York, N.Y.) [Science] 2024 May 17; Vol. 384 (6697), pp. 785-792. Date of Electronic Publication: 2024 May 16.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells.

  • Authors : Qin L; NHC Key Laboratory of Radiobiology (Jilin University), School of Public Health, Jilin University, Changchun, 130021, Jilin, People's Republic of China.; Tang G

Subjects: X-linked Nuclear Protein*/X-linked Nuclear Protein*/X-linked Nuclear Protein*/genetics ; X-linked Nuclear Protein*/X-linked Nuclear Protein*/X-linked Nuclear Protein*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jan 04; Vol. 15 (1), pp. 793. Date of Electronic Publication: 2025 Jan 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  6,239 نتائج ل ""DNA damage""