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Academic Journal

New insights on anti-tumor immunity of CD8 + T cells: cancer stem cells, tumor immune microenvironment and immunotherapy.

  • Authors : Lin Y; Department of Neurosurgery, The First Hospital of China Medical University, Shenyang, 110001, China.; Song Y

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/immunology ; Immunotherapy*/Immunotherapy*/Immunotherapy*/methods ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology

  • Source: Journal of translational medicine [J Transl Med] 2025 Mar 17; Vol. 23 (1), pp. 341. Date of Electronic Publication: 2025 Mar 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

Prognostic and therapeutic potential of CXCR6 expression on CD8 + T cells in gastric cancer: a retrospective cohort study.

  • Authors : Han SH; Department of Pathology, Dong-A University College of Medicine, Busan, 49201, Republic of Korea. .; Ju MH

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/immunology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology

  • Source: BMC gastroenterology [BMC Gastroenterol] 2025 Mar 06; Vol. 25 (1), pp. 139. Date of Electronic Publication: 2025 Mar 06.Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X

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Academic Journal

Unraveling the interplay of CD8 + T cells and microRNA signaling in cancer: implications for immune dysfunction and therapeutic approaches.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Neoplasms*/Neoplasms*/Neoplasms*/immunology

  • Source: Journal of translational medicine [J Transl Med] 2024 Dec 20; Vol. 22 (1), pp. 1131. Date of Electronic Publication: 2024 Dec 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

Establishment of a CD8+ T cells-related prognostic risk model for acral melanoma based on single-cell and bulk RNA sequencing.

  • Authors : Wang W; Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Stem Cell and Regenerative Medicine Lab, Department of Medical Science Research Center, State Key Laboratory for Complex, Severe, and Rare Diseases, Center for Translational Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; Melanoma*/Melanoma*/Melanoma*/genetics ; Melanoma*/Melanoma*/Melanoma*/immunology

  • Source: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] Publisher: Blackwell Country of Publication: England NLM ID: 9504453 Publication Model: Print Cited Medium: Internet ISSN: 1600-0846 (Electronic)

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Academic Journal

High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8 + T cells in dMMR/MSI-H gastric cancer.

  • Authors : Kanoda R; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.; Nakajima S

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/immunology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Sep 06; Vol. 14 (1), pp. 20859. Date of Electronic Publication: 2024 Sep 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

In situ analysis of CCR8 + regulatory T cells in lung cancer: suppression of GzmB + CD8 + T cells and prognostic marker implications.

  • Authors : Hayashi Y; Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.

Subjects: T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/immunology ; T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/metabolism ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/immunology

  • Source: BMC cancer [BMC Cancer] 2024 May 23; Vol. 24 (1), pp. 627. Date of Electronic Publication: 2024 May 23.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Self-Degradable Nanogels Reshape Immunosuppressive Tumor Microenvironment via Drug Repurposing Strategy to Reactivate Cytotoxic CD8 + T Cells.

  • Authors : Tian H; Cancer Center and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, Macau SAR, 999078, China.; MoE Frontiers Science Center for Precision Oncology, University of Macau, Macau, Macau SAR, 999078, China.

Subjects: CD8-Positive T-Lymphocytes* ; Tumor Microenvironment*; Nanogels

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Jul; Vol. 10 (21), pp. e2301661. Date of Electronic Publication: 2023 May 05.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Tumor-infiltrating CD36 + CD8 + T cells determine exhausted tumor microenvironment and correlate with inferior response to chemotherapy in non-small cell lung cancer.

  • Authors : Ao YQ; Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, P. R. China.; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/immunology ; CD8-Positive T-Lymphocytes*

  • Source: BMC cancer [BMC Cancer] 2023 Apr 21; Vol. 23 (1), pp. 367. Date of Electronic Publication: 2023 Apr 21.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Prognostic significance of CD8+ T-cells density in stage III colorectal cancer depends on SDF-1 expression.

  • Authors : Lalos A; University Center for Gastrointestinal and Liver Diseases, Clarunis, University of Basel, Basel, Switzerland. .; Tülek A

Subjects: CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/CD8-Positive T-Lymphocytes/*immunology ; Chemokine CXCL12/Chemokine CXCL12/Chemokine CXCL12/*biosynthesis ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*immunology

  • Source: Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 775. Date of Electronic Publication: 2021 Jan 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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