نتائج البحث

Paradoxical attenuation of early amyloid-induced cognitive impairment and synaptic plasticity in an aged APP/Tau bigenic rat model.

• Authors : Emmerson JT; Department of Pharmacology & Therapeutics, McGill University, McIntyre Medical Building, 3655 Promenade Sir William Osler Room 1210, Montreal, H3G 1Y6, Canada.; Do Carmo S

Subjects: Neuronal Plasticity*/Neuronal Plasticity*/Neuronal Plasticity*/physiology ; Rats, Transgenic* ; tau Proteins*/tau Proteins*/tau Proteins*/metabolism

• Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Dec 20; Vol. 12 (1), pp. 193. Date of Electronic Publication: 2024 Dec 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Navigating Alzheimer's Disease Mouse Models: Age-Related Pathology and Cognitive Deficits.

• Authors : De Plano LM; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.; Saitta A

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology

• Source: Biomolecules [Biomolecules] 2024 Nov 05; Vol. 14 (11). Date of Electronic Publication: 2024 Nov 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Genetic-based patient stratification in Alzheimer's disease.

• Authors : Hernández-Lorenzo L; Department of Computer Architecture and Automation, Computer Science Faculty, Complutense University of Madrid, 28040, Madrid, Spain. .; García-Gutiérrez F

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging ; tau Proteins*/tau Proteins*/tau Proteins*/genetics

• Source: Scientific reports [Sci Rep] 2024 Apr 30; Vol. 14 (1), pp. 9970. Date of Electronic Publication: 2024 Apr 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation.

• Authors : Iacono D; DoD/USU Brain Tissue Repository and Neuropathology Program, Uniformed Services University (USU), Bethesda, MD, USA. .; Department of Neurology, F. Edward Hébert School of Medicine, Uniformed Services University (USU), Bethesda, MD, USA. .

Subjects: tau Proteins*/tau Proteins*/tau Proteins*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism; Animals

• Source: Scientific reports [Sci Rep] 2023 Nov 30; Vol. 13 (1), pp. 21142. Date of Electronic Publication: 2023 Nov 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Alzheimer's Disease Animal Models: Elucidation of Biomarkers and Therapeutic Approaches for Cognitive Impairment.

• Authors : Nakai T; Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan.; Yamada K

Subjects: Disease Models, Animal*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 May 24; Vol. 22 (11). Date of Electronic Publication: 2021 May 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus.

• Authors : Rodriguez GA; Taub Institute for Research on Alzheimer's disease and the Aging Brain, Columbia University Irving Medical Center, New York, New York, United States of America.; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, United States of America.

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*genetics ; Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*genetics ; Entorhinal Cortex/Entorhinal Cortex/Entorhinal Cortex/*metabolism

• Source: PLoS biology [PLoS Biol] 2020 Aug 21; Vol. 18 (8), pp. e3000851. Date of Electronic Publication: 2020 Aug 21 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Molecular Mechanisms of Alzheimer's Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal Therapy.

• Authors : Ahn, Eun Hee^1,2 (AUTHOR) ; Park, Jae-Bong^3,4,5 (AUTHOR)

• Source: Cells (2073-4409). Jan2025, Vol. 14 Issue 2, p89. 46p.

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Advancing Alzheimer's Disease Modelling by Developing a Refined Biomimetic Brain Microenvironment for Facilitating High-Throughput Screening of Pharmacological Treatment Strategies.

• Authors : Mohd Murshid, Nuraqila¹ (AUTHOR) ; Mohd Sahardi, Nur Fatin Nabilah² (AUTHOR) ; Makpol, Suzana¹ (AUTHOR)

Subjects: *TAU proteins; *ALZHEIMER'S disease; *DRUG discovery

• Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p241. 21p.

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Selenium and Zinc against Aβ 25-35 -Induced Cytotoxicity and Tau Phosphorylation in PC12 Cells and Inhibits γ-cleavage of APP.

• Authors : Li GZ; Department of Psychiatry, Yanbian Brain Hospital, Yanji, Jilin, 133000, China.; Liu F

Subjects: Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/Amyloid Precursor Protein Secretases/*metabolism ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*pharmacology ; Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/Amyloid beta-Protein Precursor/*metabolism

• Source: Biological trace element research [Biol Trace Elem Res] 2018 Aug; Vol. 184 (2), pp. 442-449. Date of Electronic Publication: 2017 Oct 28.Publisher: Humana Press Country of Publication: United States NLM ID: 7911509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis.

• Authors : Agah, Elmira^1,2 (AUTHOR); Mojtabavi, Helia^2,3 (AUTHOR); Behkar, Atefeh⁴ (AUTHOR)

• Source: Journal of Translational Medicine. 10/21/2024, Vol. 22 Issue 1, p1-15. 15p.

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