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Data and code underlying the publication: Overcoming Selection Bias in Synthetic Lethality Prediction ...

• Authors : Seale, Colm; Tepeli, Yasin; Gonçalves, Joana

Subjects: Artificial Intelligence and Image Processing; FOS: Computer and information sciences; Genetics

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Data and code underlying the publication: Overcoming Selection Bias in Synthetic Lethality Prediction ...

• Authors : Seale, Colm; Tepeli, Yasin; Gonçalves, Joana

Subjects: Artificial Intelligence and Image Processing; FOS: Computer and information sciences; Genetics

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The power and the promise of synthetic lethality for clinical application in cancer treatment

• Authors : Qian-Wen Liu; Zhi-Wen Yang; Qing-Hai Tang

Subjects: Synthetic lethality; Cancer; Drug

• Source: Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116288- (2024)

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The biological essence of synthetic lethality: Bringing new opportunities for cancer therapy

• Authors : Meiyi Ge; Jian Luo; Yi Wu

Subjects: cancer therapy; cell–cell interaction; genome stability

• Source: MedComm – Oncology, Vol 3, Iss 1, Pp n/a-n/a (2024)

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Synthetic Lethality between Cohesin and WNT Signaling Pathways in Diverse Cancer Contexts

• Authors : Maria Michela Pallotta; Maddalena Di Nardo; Antonio Musio

Subjects: cohesin; WNT; β-catenin

• Source: Cells, Vol 13, Iss 7, p 608 (2024)

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Synthetic lethality and the minimal genome size problem

• Authors : Sara Rahiminejad; Bianca De Sanctis; Pavel Pevzner

Subjects: synthetic lethality; minimal gene set; minimal genome size

• Source: mSphere, Vol 9, Iss 7 (2024)

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Magnetic-driven hydrogel microrobots for promoting osteosarcoma chemo-therapy with synthetic lethality strategy

• Authors : Yining Tao; Leike Li; Xiyu Yang

Subjects: microrobots; magnetic-driven; drug delivery system

• Source: Frontiers in Chemistry, Vol 12 (2024)

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PARP inhibitor synthetic lethality in ATM biallelic mutant cancer cell lines is associated with BRCA1/2 and RAD51 downregulation

• Authors : Asli Muvaffak; Kevin G. Coleman

Subjects: ATM kinase; DNA double strand break (DSB) repair; homologous recombination deficiency

• Source: Frontiers in Oncology, Vol 14 (2024)

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Therapeutic Role of Synthetic Lethality in ARID1A-Deficient Malignancies

• Authors : Kyaw Z. Hein; Bettzy Stephen; Siqing Fu

Subjects: arid1a; parp; ezh2

• Source: Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 41-52 (2024)

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Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in KrasG12D-driven tumors

• Authors : Patricia Santofimia-Castaño; Nicolas Fraunhoffer; Xi Liu

Subjects: Kras; ZZW-115; Synthetic Lethality

• Source: EMBO Molecular Medicine, Vol 16, Iss 3, Pp 475-505 (2024)

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