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Academic Journal

Deconvolving multiplexed protease signatures with substrate reduction and activity clustering.

  • Authors : Zhuang Q; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, United States of America.; Holt BA

Subjects: Peptide Hydrolases*/Peptide Hydrolases*/Peptide Hydrolases*/analysis ; Peptide Hydrolases*/Peptide Hydrolases*/Peptide Hydrolases*/chemistry ; Peptide Hydrolases*/Peptide Hydrolases*/Peptide Hydrolases*/classification

  • Source: PLoS computational biology [PLoS Comput Biol] 2019 Sep 03; Vol. 15 (9), pp. e1006909. Date of Electronic Publication: 2019 Sep 03 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Structural basis for broad substrate specificity of UDP-glucose 4-epimerase in the human milk oligosaccharide catabolic pathway of Bifidobacterium longum.

  • Authors : Nam YW; Department of Biotechnology, The University of Tokyo, Tokyo, 113-8657, Japan.; Department of Biomedical and Pharmaceutical Sciences & Structural Biology Research Center, Chapman University School of Pharmacy, Irvine, CA 92618, USA.

Subjects: Bifidobacterium longum/Bifidobacterium longum/Bifidobacterium longum/*metabolism ; Catalytic Domain/Catalytic Domain/Catalytic Domain/*physiology ; Milk, Human/Milk, Human/Milk, Human/*metabolism

  • Source: Scientific reports [Sci Rep] 2019 Jul 31; Vol. 9 (1), pp. 11081. Date of Electronic Publication: 2019 Jul 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Crius: A novel fragment-based algorithm of de novo substrate prediction for enzymes.

  • Authors : Yao Z; State Key Laboratory of Bioreactor Engineering, East China university of Science and Technology, Meilong Road 130th, Shanghai, People's Republic of China.; Jiang S

Subjects: Algorithms* ; Software*; Enzymes/Enzymes/Enzymes/*chemistry

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2018 Aug; Vol. 27 (8), pp. 1526-1534. Date of Electronic Publication: 2018 Jul 18.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

A measure of the broad substrate specificity of enzymes based on 'duplicate' catalytic residues.

  • Authors : Chakraborty S; Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India. ; Ásgeirsson B

Subjects: Models, Biological* ; Models, Molecular*; Catalytic Domain/Catalytic Domain/Catalytic Domain/*genetics

  • Source: PloS one [PLoS One] 2012; Vol. 7 (11), pp. e49313. Date of Electronic Publication: 2012 Nov 16.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potential.

  • Authors : Miners JO; Department of Clinical Pharmacology, Flinders University School of Medicine, Adelaide, Australia. ; Mackenzie PI

Subjects: Metabolic Clearance Rate* ; Substrate Specificity*; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*metabolism

  • Source: Drug metabolism reviews [Drug Metab Rev] 2010 Feb; Vol. 42 (1), pp. 196-208.Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print Cited Medium: Internet ISSN: 1097-9883

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Academic Journal

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases.

  • Authors : Brown NR; Laboratory of Molecular Biophysics and Oxford Centre for Molecular Sciences, Department of Biochemistry, University of Oxford, Rex Richards Building, South Parks Road, Oxford OX1 3QU, UK.; Noble ME

Subjects: CDC2-CDC28 Kinases* ; Substrate Specificity*; Cyclin A/Cyclin A/Cyclin A/*chemistry

  • Source: Nature cell biology [Nat Cell Biol] 1999 Nov; Vol. 1 (7), pp. 438-43.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print Cited Medium: Print ISSN: 1465-7392

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Academic Journal

Growth of complete ammonia oxidizers on guanidine

Subjects: Models, Molecular; Proteomics; Nitrogen

  • Source: NaturePalatinszky, M, Herbold, C W, J. Sedlacek, C, Pühringer, D, Kitzinger, K, Giguere, A T, Wasmund, K, Nielsen, P H, Dueholm, M K D, Jehmlich, N, Gruseck, R, Legin, A, Kostan, J, Krasnici,

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