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Academic Journal

A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence.

  • Authors : Shaikh SB; Department of Environmental Medicine, University of Rochester Medical Centre, 601 Elmwood Avenue, Box 850, Rochester, NY, 14642, USA.; Balaya RDA

Subjects: Cellular Senescence* ; Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/metabolism ; Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/Plasminogen Activator Inhibitor 1*/genetics

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Nov 14; Vol. 22 (1), pp. 544. Date of Electronic Publication: 2024 Nov 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

A guide to ERK dynamics, part 1: mechanisms and models.

  • Authors : Ram A; Department of Molecular and Cellular Biology, University of California, Davis, U.S.A.; Murphy D

Subjects: Extracellular Signal-Regulated MAP Kinases*/Extracellular Signal-Regulated MAP Kinases*/Extracellular Signal-Regulated MAP Kinases*/metabolism ; Signal Transduction*; Phosphorylation

  • Source: The Biochemical journal [Biochem J] 2023 Dec 13; Vol. 480 (23), pp. 1887-1907.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.

  • Authors : Luo L; State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy/School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Wang H

Subjects: Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/drug therapy ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/metabolism ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/pathology

  • Source: PloS one [PLoS One] 2024 May 16; Vol. 19 (5), pp. e0303556. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Editorial & Opinion

MAPK-ERK Pathway.

  • Authors : Park JI; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Subjects: Extracellular Signal-Regulated MAP Kinases*/Extracellular Signal-Regulated MAP Kinases*/Extracellular Signal-Regulated MAP Kinases*/metabolism ; Signal Transduction*/Signal Transduction*/Signal Transduction*/physiology; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 02; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer.

  • Authors : Gottumukkala SB; Department of Biotechnology, National Institute of Technology Warangal, Warangal, India.; Ganesan TS

Subjects: Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/genetics ; Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/physiology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics

  • Source: NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 May 17; Vol. 10 (1), pp. 53. Date of Electronic Publication: 2024 May 17.Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model:

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Academic Journal

Senescence and Stress Signaling Pathways in Corneal Cells After Nitrogen Mustard Injury.

  • Authors : Anwar KN; Department of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL 60612, USA.; Soleimani M

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; Mechlorethamine*/Mechlorethamine*/Mechlorethamine*/toxicity ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: Cells [Cells] 2024 Dec 06; Vol. 13 (23). Date of Electronic Publication: 2024 Dec 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

RON receptor tyrosine kinase regulates glycolysis through MAPK/CREB signaling to affect ferroptosis and chemotherapy sensitivity of thyroid cancer cells.

  • Authors : Jin X; School of Medicine, Shaoxing University, Shaoxing, Zhejiang 312000, P.R. China.; Zhu H

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Cyclic AMP Response Element-Binding Protein*/Cyclic AMP Response Element-Binding Protein*/Cyclic AMP Response Element-Binding Protein*/metabolism ; Glycolysis*/Glycolysis*/Glycolysis*/drug effects

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Dec; Vol. 30 (6). Date of Electronic Publication: 2024 Oct 18.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The MAPK/ERK channel capacity exceeds 6 bit/hour.

Subjects: MAP Kinase Signaling System*/MAP Kinase Signaling System*/MAP Kinase Signaling System*/physiology ; Signal Transduction*; Cell Line

  • Source: PLoS computational biology [PLoS Comput Biol] 2023 May 22; Vol. 19 (5), pp. e1011155. Date of Electronic Publication: 2023 May 22 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

mGluR1/IP3/ERK signaling pathway regulates vestibular compensation in ON UBCs of the cerebellar flocculus.

  • Authors : Liu D; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Institute of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Subjects: Extracellular Signal-Regulated MAP Kinases* ; Signal Transduction* ; Benzoates*

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14419. Date of Electronic Publication: 2023 Aug 25.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Electric field modulation of ERK dynamics shows dependency on waveform and timing.

  • Authors : Hu M; School of Molecular Sciences, Arizona State University, Tempe, AZ, 85287, USA.; Li H

Subjects: Signal Transduction* ; MAP Kinase Signaling System*/MAP Kinase Signaling System*/MAP Kinase Signaling System*/physiology; Cell Differentiation

  • Source: Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3167. Date of Electronic Publication: 2024 Feb 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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