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Academic Journal

Inhibition of HSP90 S-nitrosylation alleviates cardiac fibrosis via TGFβ/SMAD3 signalling pathway.

Authors : Zhang X; Key Laboratory of Cardiovascular and Cerebrovascular Medicine, Nanjing Medical University, Nanjing, China.; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China.

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Signal Transduction*; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*metabolism

Source: British journal of pharmacology [Br J Pharmacol] 2021 Dec; Vol. 178 (23), pp. 4608-4625. Date of Electronic Publication: 2021 Oct 24.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways.

Authors : Sun P; Department of Reproductive Physiology, Zhejiang Academy of Medical Sciences / Hangzhou Medical College, 310013, Hangzhou, Zhejiang, China.; Wang Y

Subjects: HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors ; Signal Transduction/Signal Transduction/Signal Transduction/*drug effects ; Sperm Capacitation/Sperm Capacitation/Sperm Capacitation/*drug effects

Source: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2021 Mar 04; Vol. 19 (1), pp. 39. Date of Electronic Publication: 2021 Mar 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101153627 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7827

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Academic Journal

HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF).

Authors : Colunga Biancatelli RML; Frank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA.; Policlinico Umberto I, La Sapienza University of Rome, 00185 Rome, Italy.

Subjects: Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/drug therapy ; Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/metabolism ; Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 25; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2.

Authors : Byrne DP; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 7ZB, U.K.; Shrestha S

Subjects: Protein Kinases*/Protein Kinases*/Protein Kinases*/metabolism ; Signal Transduction*; Animals

Source: The Biochemical journal [Biochem J] 2023 Jan 31; Vol. 480 (2), pp. 141-160.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Aspirin Enhances the Protection of Hsp90 from Heat-Stressed Injury in Cardiac Microvascular Endothelial Cells Through PI3K-Akt and PKM2 Pathways.

Authors : Zhang X; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Chen B

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Aspirin/Aspirin/Aspirin/*pharmacology ; Cytoprotection/Cytoprotection/Cytoprotection/*drug effects

Source: Cells [Cells] 2020 Jan 18; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans .

Authors : Lissemore JL; Biology Department, John Carroll University, University Heights, OH 44118 .; Connors E

Subjects: Signal Transduction*; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*metabolism ; Caenorhabditis elegans Proteins/Caenorhabditis elegans Proteins/Caenorhabditis elegans Proteins/*metabolism

Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 May 04; Vol. 8 (5), pp. 1535-1544. Date of Electronic Publication: 2018 May 04.Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Baicalin Targets HSP70/90 to Regulate PKR/PI3K/AKT/eNOS Signaling Pathways.

Authors : Hou Y; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, National Centre for Mass Spectrometry in Beijing, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; College of Chemical Science, University of Chinese Academy of Sciences, Beijing 100049, China.

Subjects: Flavonoids/Flavonoids/Flavonoids/*pharmacology ; HSP70 Heat-Shock Proteins/HSP70 Heat-Shock Proteins/HSP70 Heat-Shock Proteins/*antagonists & inhibitors ; HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/HSP90 Heat-Shock Proteins/*antagonists & inhibitors

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Feb 21; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.

Authors : Qin M; Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.; Xin Y

Subjects: Proteolysis*/Proteolysis*/Proteolysis*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Ubiquitination*/Ubiquitination*/Ubiquitination*/drug effects

Source: Cells [Cells] 2022 Jan 13; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Extracellular heat shock protein 90α mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling.

Authors : Dong HM; Chronic Airways Diseases Laboratory, Department of Respiratory and Critical Care Medicine, NanFang Hospital, Southern Medical University, Guangzhou, 510515, China.; Le YQ

Subjects: Anti-Asthmatic Agents/Anti-Asthmatic Agents/Anti-Asthmatic Agents/*pharmacology ; Bronchi/Bronchi/Bronchi/*drug effects ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*drug effects

Source: Respiratory research [Respir Res] 2017 May 30; Vol. 18 (1), pp. 111. Date of Electronic Publication: 2017 May 30.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Emerging Roles of Cancer Stem Cells in Bladder Cancer Progression, Tumorigenesis, and Resistance to Chemotherapy: A Potential Therapeutic Target for Bladder Cancer.

Authors : Abugomaa A; Laboratory of Veterinary Pharmacology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.; Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Dakahliya, Egypt.

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/genetics

Source: Cells [Cells] 2020 Jan 17; Vol. 9 (1). Date of Electronic Publication: 2020 Jan 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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نتائج البحث

فلترة النتائج

Inhibition of HSP90 S-nitrosylation alleviates cardiac fibrosis via TGFβ/SMAD3 signalling pathway.

Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways.

HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF).

Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2.

Aspirin Enhances the Protection of Hsp90 from Heat-Stressed Injury in Cardiac Microvascular Endothelial Cells Through PI3K-Akt and PKM2 Pathways.

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans .

Baicalin Targets HSP70/90 to Regulate PKR/PI3K/AKT/eNOS Signaling Pathways.

Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.

Extracellular heat shock protein 90α mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling.

Emerging Roles of Cancer Stem Cells in Bladder Cancer Progression, Tumorigenesis, and Resistance to Chemotherapy: A Potential Therapeutic Target for Bladder Cancer.

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