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PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest (PROSPER)

• Source: Beretta S, Padovano G, Stabile A, Coppo A, Bogliun G, Avalli L, Ferrarese C. Efficacy and safety of perampanel oral loading in postanoxic super-refractory status

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A Study to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Participants With Focal Onset Seizures With or Without Focal to Bilateral Tonic-clonic Seizures

• Source: A Multicenter, Open-Label, Prospective Study With an Extension Phase to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Subjects With Focal Onset

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Efficacy, safety, and tolerability of adjunctive perampanel in patients from China with focal seizures or generalized tonic-clonic seizures: Post hoc analysis of phase III double-blind and open-label extension studies.

• Authors : Weiping L; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Guangdong, China.; Dong Z

Subjects: Anticonvulsants/Anticonvulsants/Anticonvulsants/*administration & dosage ; Nitriles/Nitriles/Nitriles/*administration & dosage ; Pyridones/Pyridones/Pyridones/*administration & dosage

• Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2021 Mar; Vol. 27 (3), pp. 330-340.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Effect of Perampanel on Peritumoral Hyperexcitability in HGG

• Authors : National Cancer Institute (NCI); Eisai Inc.; Jong Woo Lee, MD PhD, Principal Investigator

• Source: Pilot Study of Perampanel on Peritumoral Hyperexcitability and Seizure Control in Newly Diagnosed High Grade Glioma

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Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam

• Authors : Zolkowska, Dorota; Dhir, Ashish; Rogawski, Michael A

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Neurosciences

• Source: Archives of Toxicology. 95(7)

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A Study to Evaluate the Effectiveness of Perampanel as Only Add-on Treatment in Participants With Primary or Secondarily Generalized Tonic-clonic Seizures

• Source: PERPRISE: A Prospective Non-interventional Study Evaluating the Effectiveness of Perampanel (Fycompa®) as Only Add-on Treatment in Patients With Primary or Secondarily

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Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

• Authors : William Tatum, DO, Principal Investigator

• Source: A Phase IV, Prospective, Open-Label, Parallel Study Evaluating the Effect of an Adjunctive Anti-Seizure Medication Using a Glutamatergic Modulator in Patients With Focal Epilepsy and High-Grade Glioma

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A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

• Source: An Open-Label Study With Extension Phase to Evaluate the Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Subjects (Age 1 Month to

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An Extended Access Program (EAP) for Perampanel

• Source: An Extended Access Program (EAP) for Perampanel

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A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

• Source: A Prospective, Non-Interventional, Observational, Multicenter Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Adjunctive Therapy

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