نتائج البحث

Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially.

• Authors : Akbib S; Unit Diabetes Pathology and Therapy, Diabetes Research Cluster, Vrije Universiteit Brussel, Brussels, Belgium.; Stichelmans J

Subjects: G1 Phase/G1 Phase/G1 Phase/*drug effects ; Glucocorticoids/Glucocorticoids/Glucocorticoids/*pharmacology ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*metabolism

• Source: PloS one [PLoS One] 2019 Feb 19; Vol. 14 (2), pp. e0212210. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

• Authors : Geoffrey T. Norris; Cynthia Winter; Kristopher R. Bosse

Subjects: Oncogene Proteins; 0301 basic medicine; N-Myc Proto-Oncogene Protein

• Source: Proceedings of the National Academy of Sciences. 108:3336-3341

تفاصيل العنوان

Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses.

• Authors : Hsiao, Hao-Wen^1,2 (AUTHOR); Yang, Chi-Chun¹ (AUTHOR); Masai, Hisao^1,2 (AUTHOR)

• Source: Biomolecules (2218-273X). Jan2023, Vol. 13 Issue 1, p125. 23p.

تفاصيل العنوان

A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts.

• Authors : Bélanger F; Département de Médecine, Université de Montréal and Centre de Recherche, Hôpital Maisonneuve Rosemont, Montréal, Québec, Canada.; Rajotte V

Subjects: S Phase*; DNA Repair/DNA Repair/DNA Repair/*genetics ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*radiation effects

• Source: PloS one [PLoS One] 2014 Jan 08; Vol. 9 (1), pp. e85294. Date of Electronic Publication: 2014 Jan 08 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements.

• Authors : Rybaczek D; Department of Cytophysiology, University of Łódź, Pilarskiego 14, 90-231, Łódź, Poland. ; Kowalewicz-Kulbat M

Subjects: Chromosomes, Human/Chromosomes, Human/Chromosomes, Human/*drug effects ; Chromosomes, Human/Chromosomes, Human/Chromosomes, Human/*metabolism ; Cytoskeleton/Cytoskeleton/Cytoskeleton/*drug effects

• Source: Histochemistry and cell biology [Histochem Cell Biol] 2011 Mar; Vol. 135 (3), pp. 263-80. Date of Electronic Publication: 2011 Feb 24.Publisher: Springer Country of Publication: Germany NLM ID: 9506663 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-119X

تفاصيل العنوان

Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition.

• Authors : Fragel-Madeira L; Institute of Biophysics, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Meletti T

Subjects: G2 Phase* ; S Phase*; Cell Nucleus/Cell Nucleus/Cell Nucleus/*physiology

• Source: PloS one [PLoS One] 2011 Jan 27; Vol. 6 (1), pp. e16058. Date of Electronic Publication: 2011 Jan 27.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

تفاصيل العنوان

XPA-mediated regulation of global nucleotide excision repair by ATR Is p53-dependent and occurs primarily in S-phase.

• Authors : Li Z; Department of Biochemistry and Molecular Biology, East Tennessee State University, JH Quillen College of Medicine, Johnson City, Tennessee, United States of America.; Musich PR

Subjects: DNA Repair*/DNA Repair*/DNA Repair*/radiation effects ; S Phase*/S Phase*/S Phase*/radiation effects; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism

• Source: PloS one [PLoS One] 2011; Vol. 6 (12), pp. e28326. Date of Electronic Publication: 2011 Dec 12.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

تفاصيل العنوان

Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.

• Authors : Li G; Department of Pathology, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.; Park HU

Subjects: Cell Division* ; G2 Phase* ; S Phase*

• Source: Retrovirology [Retrovirology] 2010 Jul 07; Vol. 7, pp. 59. Date of Electronic Publication: 2010 Jul 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101216893 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-4690

تفاصيل العنوان

Chk1 regulates the density of active replication origins during the vertebrate S phase.

• Authors : Maya-Mendoza A; Faculty of Life Sciences, University of Manchester, MIB, Manchester, UK.; Petermann E

Subjects: DNA Replication/DNA Replication/DNA Replication/*genetics ; Protein Kinases/Protein Kinases/Protein Kinases/*metabolism ; Replication Origin/Replication Origin/Replication Origin/*genetics

• Source: The EMBO journal [EMBO J] 2007 Jun 06; Vol. 26 (11), pp. 2719-31. Date of Electronic Publication: 2007 May 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Print ISSN:

تفاصيل العنوان

HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.

• Authors : Collis SJ; DNA Damage Response Laboratory, Cancer Research UK, The London Research Institute, Clare Hall Laboratories, South Mimms, EN6 3LD, UK.; Barber LJ

Subjects: Protein Kinases/Protein Kinases/Protein Kinases/*metabolism ; Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*physiology ; S Phase/S Phase/S Phase/*physiology

• Source: Nature cell biology [Nat Cell Biol] 2007 Apr; Vol. 9 (4), pp. 391-401. Date of Electronic Publication: 2007 Mar 25.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Print ISSN:

تفاصيل العنوان