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HELLS regulates transcription in T-cell lymphomas by reducing unscheduled R-loops and by facilitating RNAPII progression.

• Authors : Tameni A; Laboratory of Translational Research, Azienda USL-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123, Reggio Emilia, Italy.; Mallia S

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; R-Loop Structures* ; Transcription, Genetic*

• Source: Nucleic acids research [Nucleic Acids Res] 2024 Jun 24; Vol. 52 (11), pp. 6171-6182.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Multi-omics to characterize the functional relationships of R-loops with epigenetic modifications, RNAPII transcription and gene expression.

• Authors : Pan X; Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Huang LF

Subjects: R-Loop Structures* ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism

• Source: Briefings in bioinformatics [Brief Bioinform] 2022 Jul 18; Vol. 23 (4).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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RNA helicase D1PAS1 resolves R-loops and forms a complex for mouse pachytene piRNA biogenesis required for male fertility.

• Authors : Choi, Heejin¹ (AUTHOR) ; Zhou, Lecong¹ (AUTHOR); Zhao, Yangu¹ (AUTHOR)

Subjects: *RNA polymerase II; *RNA helicase; *GENE expression

• Source: Nucleic Acids Research. 10/28/2024, Vol. 52 Issue 19, p11973-11994. 22p.

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Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

• Authors : Zhang, Xuan; Xu, Jun; Hu, Jing

Subjects: Biological Sciences; Bioinformatics and Computational Biology; Biomedical and Clinical Sciences

• Source: Nature Communications. 15(1)

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FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress.

• Authors : Okamoto Y; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Japan.; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Japan.

Subjects: DNA Replication* ; Genomic Instability*; DEAD-box RNA Helicases/DEAD-box RNA Helicases/DEAD-box RNA Helicases/*metabolism

• Source: The FEBS journal [FEBS J] 2019 Jan; Vol. 286 (1), pp. 139-150. Date of Electronic Publication: 2018 Nov 27.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Mechanisms of SOSS‐Integrator–PP2A complex in attenuating R‐loops and promoting genome stability.

• Authors : Wang, Jingwen^1,2 (AUTHOR); Xu, Conglin³ (AUTHOR); Zhang, Zhen^1,2 (AUTHOR)

• Source: Clinical & Translational Medicine. Jan2024, Vol. 14 Issue 1, p1-3. 3p.

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DNA Topoisomerase I differentially modulates R-loops across the human genome

• Authors : Manzo, Stefano G; Hartono, Stella R; Sanz, Lionel A

Subjects: Genetics; Underpinning research; 1.1 Normal biological development and functioning

• Source: Genome Biology. 19(1)

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The rDNA is biomolecular condensate formed by polymer–polymer phase separation and is sequestered in the nucleolus by transcription and R-loops

• Authors : Josh Lawrimore; Elaine Yeh; Muznah Khan

Subjects: Saccharomyces cerevisiae Proteins; AcademicSubjects/SCI00010; Polymers

• Source: Nucleic Acids Research

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R-loops enhance polycomb repression at a subset of developmental regulator genes

• Authors : Skourti-Stathaki, Konstantina; Torlai Triglia, Elena; Warburton, Marie

Subjects: poising; Cardiovascular and Metabolic Diseases; fungi

• Source: Skourti-Stathaki, K, Torlai Triglia, E, Warburton, M, Voigt, P, Bird, A & Pombo, A 2019, ' R-Loops Enhance Polycomb Repression at a Subset

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R-loops at microRNA encoding loci promote co-transcriptional processing of pri-miRNAs in plants

• Authors : Lucia Gonzalo; Ileana Tossolini; Tomasz Gulanicz

Subjects: MicroRNAs; Animals; RNA Polymerase II

• Source: Gonzalo, L, Tossolini, I, Gulanicz, T, Cambiagno, D A, Kasprowicz-Maluski, A, Smolinski, D J, Mammarella, M F, Ariel, F D, Marquardt, S, Szweykowska-Kulinska, Z, Jarmolowski, A & Manavella, P A 2022,

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