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HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via PHLDA1 Induction

• Authors : Clayton, Natasha S; Carter, Edward P; Fearon, Abbie E

Subjects: Humans; Female; Lapatinib/pharmacology

• Source: Clayton , N S , Carter , E P , Fearon , A E , Heward , J A , Rodríguez Fernández , L , Boughetane , L , Wilkes , E H , Cutillas , P R & Grose , R P 2023 , ' HDAC Inhibition Restores Response to

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Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis

• Authors : Hyunho Yoon; Chih-Min Tang; Sudeep Banerjee

Subjects: Cancer-Associated Fibroblasts / drug effects; Cancer-Associated Fibroblasts / pathology; Cell Line

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CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer.

• Authors : Yang, Z.; Liang, S.Q.; Yang, H.

Subjects: Aged; Animals; Apoptosis

• Source: Cancer research, vol. 81, no. 11, pp. 3121-3133

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EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer

• Authors : Rose, Michael; Maurer, Angela; Wirtz, Julia

Subjects: Bladder cancer; Gene Expression Regulation; Neoplastic [MeSH]

• Source: http://lobid.org/resources/99370678536806441#!, 39(44):6856-6870.

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Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia

• Authors : Kloos, Arnold; Mintzas, Konstantinos; Winckler, Lina

Subjects: Leukemia; Myelomonocytic; Chronic/pathology [MeSH]

• Source: http://lobid.org/resources/99370672770606441#!, 34(11):2951-2963.

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Rebound pathway overactivation by cancer cells following discontinuation of PI3K or mTOR inhibition promotes cancer cell growth.

• Authors : Faes, S.; Santoro, T.; Troquier, L.

Subjects: Antineoplastic Agents/pharmacology; Cell Line; Tumor

• Source: Biochemical and biophysical research communications, vol. 513, no. 3, pp. 546-552

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Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors.

• Authors : Spender, Lindsay C.; Ferguson, G. John; Hughes, Gareth D.

Subjects: Activin Receptors; Type I/metabolism; Animals

• Source: Spender , L C , Ferguson , G J , Hughes , G D , Davies , B R , Goldberg , F W , Herrera , B , Taylor , R G , Strathearn , L , Sansom , O J , Barry , S T & Inman , G 2019 , ' Preclinical Evaluation of

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Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors

• Authors : Archer, Caroline R; Robinson, Emma L; Drawnel, Faye M

Subjects: Animals; Newborn; Cardiomegaly/genetics

• Source: Archer , C R , Robinson , E L , Drawnel , F M & Roderick , H L 2017 , ' Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription

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Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

• Authors : College of Medicine; Dept. of Internal Medicine; Sun Min Lim

Subjects: Adult; Aged; 80 and over

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Next-generation epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor -mutant non-small cell lung cancer

• Authors : College of Medicine; Dept. of Internal Medicine; Chee-Seng Tan

Subjects: Animals; Antineoplastic Agents/pharmacology; Antineoplastic Agents/therapeutic use

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