نتائج البحث

Resveratrol analogues and metabolites selectively inhibit human and rat 11β-hydroxysteroid dehydrogenase 1 as the therapeutic drugs: structure–activity relationship and molecular dynamics analysis

• Authors : C, Hu; Y, Zhai; H, Lin

Subjects: 0301 basic medicine; Quantitative Structure-Activity Relationship; Molecular Dynamics Simulation

• Source: SAR and QSAR in Environmental Research. 35:641-663

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Structure-activity relationship studies of pyrogallol as a calcineurin/NFAT signaling suppressor

• Authors : Hiroyuki Mizuguchi; Tomohira Ito; Kohei Nishida

Subjects: Structure-Activity Relationship; NFATC Transcription Factors; Calcineurin

• Source: Journal of Pharmacological Sciences. 155:140-147

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Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior

• Authors : Angelia, Jeannes; Weng, Xiaohui; Solomatov, Aleksei

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Chronic Pain

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Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors

• Authors : Wilt, Stephanie; Kodani, Sean; Valencia, Leah

Subjects: Medicinal and Biomolecular Chemistry; Chemical Sciences; Chronic Pain

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Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5‑a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies

• Authors : Oukoloff, Killian; Nzou, Goodwell; Varricchio, Carmine

Subjects: Brain Disorders; Aging; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)

• Source: Journal of Medicinal Chemistry. 64(2)

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Structure–Activity Relationship of Lower Chlorinated Biphenyls and Their Human-Relevant Metabolites for Astrocyte Toxicity

• Authors : Neha Paranjape; Laura E. Dean; Andres Martinez

Subjects: Rats, Sprague-Dawley; Mice, Inbred C57BL; Mice

• Source: Chem Res Toxicol

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Structure–Activity Relationship of N-Ethyl-Hexedrone Analogues: Role of the α-Carbon Side-Chain Length in the Mechanism of Action, Cytotoxicity, and Behavioral Effects in Mice

• Authors : Núria Nadal-Gratacós; Edwin Ríos-Rodríguez; David Pubill

Subjects: Pyrrolidines; Estimulants; Stimulants

• Source: ACS Chem NeurosciArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)Dipòsit Digital de la UBinstname

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Synergistic Effect of Flavonoids and Metformin on Protection of the Methylglyoxal-Induced Damage in PC-12 Neuroblastoma Cells: Structure–Activity Relationship and Potential Target

• Authors : Danyang Zhang; Xiaoshi He; Ting Wang

Subjects: Flavonoids; 0301 basic medicine; structure–activity relationship

• Source: MoleculesMolecules, Vol 29, Iss 10, p 2306 (2024)

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Discovery and Structure–Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists

• Authors : Preti, Barbara; Suchankova, Anna; Deganutti, Giuseppe ...

Subjects: Structure-Activity Relationship; Adenosine; Halogens

• Source: J Med ChemPreti, Barbara; Suchankova, Anna; Deganutti, Giuseppe; Leuenberger, Michele; Barkan, Kerry; Manulak, Iga; Huang, Xianglin; Carvalho, Sabrina; Ladds, Graham; Lochner, Martin (2022).

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Antitubercular 2-Pyrazolylpyrimidinones: Structure–Activity Relationship and Mode-of-Action Studies

• Authors : Kelly Chibale; Sandile B. Simelane; Christel Brunschwig

Subjects: Male; 0303 health sciences; Iron

• Source: J Med Chem

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