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Academic Journal

Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.

Authors : Hahn, Claudine; Tyka, Karolina; Saba, Julie

Subjects: S1P-lyase; cytokine; diabetes

Source: Journal of Biological Chemistry. 292(49)

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Academic Journal

The fate of intracellular S1P regulates lipid droplet turnover and lipotoxicity in pancreatic beta-cells.

Authors : Tang, Yadi; Majewska, Mariola; Leß, Britta

Subjects: beta-cells; ceramide; diabetes

Source: Journal of Lipid Research. 65(8)

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Using recombinase‐mediated cassette exchange to engineer MIN6 insulin‐secreting cells based on a newly identified safe harbor locus

Authors : Aya Tanaka; Midori Yamana; Hisamitsu Ishihara

Subjects: Basic Science and Research; endocrine system; Endocrinology, Diabetes and Metabolism

Source: Journal of Diabetes Investigation, Vol 12, Iss 12, Pp 2129-2140 (2021)Journal of Diabetes Investigation

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Academic Journal

The ethyl acetate fraction of corn silk exhibits dual antioxidant and anti-glycation activities and protects insulin-secreting cells from glucotoxicity.

Authors : Chia-Chuan Chang¹; Wei Yuan²; Hsiao-Yuh Roan³

Subjects: *TYPE 2 diabetes treatment; *RNA analysis; *REACTIVE oxygen species

Source: BMC Complementary & Alternative Medicine. 11/3/2016, Vol. 16, p1-11. 11p. 1 Diagram, 6 Graphs.

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Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function

Authors : Anna Castle; Syed Saad Hussain; Candice M Inouye

Subjects: 0301 basic medicine; Cytoplasm; Endocytic cycle

Source: PLoS ONEPLoS ONE, Vol 13, Iss 9, p e0198383 (2018)

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Clusterin induces differentiation of pancreatic duct cells into insulin-secreting cells

Authors : Bon Hong Min; Byeong-Moo Kim; Yong Jae Shin

Subjects: Male; medicine.medical_specialty; DNA, Complementary

Source: Diabetologia. 49:311-320

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Academic Journal

The mitochondrial tRNA-derived fragment, mt-tRF-Leu TAA , couples mitochondrial metabolism to insulin secretion.

Authors : Jacovetti, C.; Donnelly, C.; Menoud, V.

Subjects: Animals; Rats; Humans

Source: Molecular metabolism, vol. 84, pp. 101955

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Academic Journal

Mechanically reinforced hydrogel vehicle delivering angiogenic factor for beta cell therapy

Authors : Toftdal, Mette Steen; Christensen, Natasja Porskjær; Kadumudi, Firoz Babu

Subjects: Beta cell; Drug release; Electrospinning

Source: Toftdal , M S , Christensen , N P , Kadumudi , F B , Dolatshahi-Pirouz , A , Grunnet , L G & Chen , M 2024 , ' Mechanically reinforced hydrogel vehicle delivering angiogenic factor for beta cell

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Academic Journal

Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes

Authors : Wang, Zhongying; Gurlo, Tatyana; Matveyenko, Aleksey V

Subjects: Biochemistry and Cell Biology; Biological Sciences; Autoimmune Disease

Source: Communications Biology. 4(1)

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Effects of the novel mitochondrial protein mimitin in insulin-secreting cells

Authors : Jolanta Jura; Sigurd Lenzen; Ewa Gurgul-Convey

Subjects: Male; medicine.medical_treatment; Gene Expression

Source: Biochemical Journal; Vol 445

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