نتائج البحث

Analysis of raltegravir analogs to enhance inhibitory efficiency against HIV integrase

• Authors : Hanieh Sabaghian; Mehdi Yoosefian

Subjects: HIV-1 integrase; Drug design; Viral disease treatment

• Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

تفاصيل العنوان

Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential

• Authors : Slavish, Peter J; Cuypers, Maxime G; Rimmer, Mary Ashley

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Antimicrobial Resistance

تفاصيل العنوان

Effectiveness of dolutegravir-based regimens compared to raltegravir-, elvitegravir-, bictegravir, and darunavir-based regimens among older adults with HIV in the Veterans Aging Cohort Study (VACS).

• Authors : Yan, Lei^1,2 (AUTHOR); Henegar, Cassidy E.³ (AUTHOR); Marconi, Vincent C.^4,5 (AUTHOR)

• Source: AIDS Research & Therapy. 12/21/2024, Vol. 21 Issue 1, p1-13. 13p.

تفاصيل العنوان

Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential

• Authors : Peter J. Slavish; Maxime G. Cuypers; Mary Ashley Rimmer

Subjects: Dibenzothiepins; 0301 basic medicine; Pyridones

• Source: European Journal of Medicinal Chemistry. 247:115035

تفاصيل العنوان

Update on Adverse Effects of HIV Integrase Inhibitors

• Authors : Kolakowska, A; Maresca, AF; Collins, IJ

Subjects: HIV Medicine (C Yoon, Section Editor); Elvitegravir; Drug-related side effects and adverse reactions

• Source: Curr Treat Options Infect Dis

تفاصيل العنوان

Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

• Authors : Daniel P. Maskell; Peter Cherepanov; Katherine Fesen ...

Subjects: DOLUTEGRAVIR; Models, Molecular; 0301 basic medicine

• Source: J Med ChemJournal of Medicinal ChemistryJournal of Medicinal Chemistry, American Chemical Society, 2017, 60 (17), pp.7315-7332. ⟨10.1021/acs.jmedchem.7b00596⟩

تفاصيل العنوان

HIV INTEGRASE INHIBITORS: THE BASIS OF EFFECTIVE AND SAFE ANTIRETROVIRAL THERAPY

• Authors : V. I. SHAKHGILDYAN

Subjects: 03 medical and health sciences; 0302 clinical medicine; Medicine

• Source: Медицинский совет, Vol 0, Iss 4, Pp 52-62 (2017)

تفاصيل العنوان

POM analyses of Raltegravir derivatives: a new reflection enlightening the mechanism of HIV-integrase inhibition.

• Authors : Lahsasni, Siham¹; Ben Hadda, Taibi² ; Masand, Vijay³

• Source: Research on Chemical Intermediates. Aug2015, Vol. 41 Issue 8, p5121-5136. 16p. 1 Color Photograph, 1 Black and White Photograph, 8 Diagrams, 2 Charts.

تفاصيل العنوان

N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase

• Authors : PESCATORI, LUCA; Metifiot, Mathieu; Chung, Suhman

Subjects: Models, Molecular; Antiviral Drugs; 0303 health sciences

• Source: Journal of Medicinal Chemistry. 58:4610-4623

تفاصيل العنوان

Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification.

• Authors : Baddock, Hannah T¹ (AUTHOR); Brolih, Sanja¹ (AUTHOR); Yosaatmadja, Yuliana² (AUTHOR)

Subjects: *INTEGRASE inhibitors; *RALTEGRAVIR; *VIRAL genomes

• Source: Nucleic Acids Research. 2/22/2022, Vol. 50 Issue 3, p1484-1500. 17p.

تفاصيل العنوان