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Academic Journal

Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.

  • Authors : Pechincha C; Cell Signaling and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Heidelberg, Germany.

Subjects: Golgi Apparatus*/Golgi Apparatus*/Golgi Apparatus*/metabolism ; Lysosomal Storage Diseases*/Lysosomal Storage Diseases*/Lysosomal Storage Diseases*/genetics ; Lysosomal Storage Diseases*/Lysosomal Storage Diseases*/Lysosomal Storage Diseases*/metabolism

  • Source: Science (New York, N.Y.) [Science] 2022 Oct 07; Vol. 378 (6615), pp. eabn5637. Date of Electronic Publication: 2022 Oct 07.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection.

  • Authors : Richards CM; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Jabs S

Subjects: COVID-19*/COVID-19*/COVID-19*/genetics ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Mucolipidoses*/Mucolipidoses*/Mucolipidoses*/genetics

  • Source: Science (New York, N.Y.) [Science] 2022 Oct 07; Vol. 378 (6615), pp. eabn5648. Date of Electronic Publication: 2022 Oct 07.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

  • Authors : Pierga A; Sorbonne Université, Paris, France.; Paris Brain Institute, ICM, Paris, France.

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Proteins*/Proteins*/Proteins*/metabolism ; Adaptor Proteins, Vesicular Transport*/Adaptor Proteins, Vesicular Transport*/Adaptor Proteins, Vesicular Transport*/metabolism

  • Source: PLoS biology [PLoS Biol] 2023 Oct 23; Vol. 21 (10), pp. e3002337. Date of Electronic Publication: 2023 Oct 23 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes.

  • Authors : Alqahtani Y; Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, South Dakota State University, 1055 Campanile Ave, Box 2202C, Brookings, SD, 57007, USA.; Wang S

Subjects: Fluorescent Dyes/Fluorescent Dyes/Fluorescent Dyes/*chemistry ; Lysosomes/Lysosomes/Lysosomes/*metabolism ; Proteins/Proteins/Proteins/*metabolism

  • Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2019 Sep; Vol. 411 (24), pp. 6463-6473. Date of Electronic Publication: 2019 Aug 26.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.

  • Authors : Tran ML; Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, USA.; Tüshaus J

Subjects: Proteins*/Proteins*/Proteins*/metabolism ; Saposins*/Saposins*/Saposins*/genetics ; Saposins*/Saposins*/Saposins*/metabolism

  • Source: Traffic (Copenhagen, Denmark) [Traffic] 2023 Jan; Vol. 24 (1), pp. 4-19.Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print Cited Medium: Internet ISSN: 1600-0854 (Electronic)

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Academic Journal

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.

  • Authors : Papadopoulos C; Molecular Biology I, Faculty of Biology, Centre for Medical Biotechnology, University of Duisburg-Essen, Essen, Germany.; Kirchner P

Subjects: Autophagy*; Adenosine Triphosphatases/Adenosine Triphosphatases/Adenosine Triphosphatases/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism

  • Source: The EMBO journal [EMBO J] 2017 Jan 17; Vol. 36 (2), pp. 135-150. Date of Electronic Publication: 2016 Oct 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The enlarged lysosomes in beige j cells result from decreased lysosome fission and not increased lysosome fusion.

  • Authors : Durchfort N; Department of Pathology, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA.; Verhoef S

Subjects: Chediak-Higashi Syndrome*/Chediak-Higashi Syndrome*/Chediak-Higashi Syndrome*/metabolism ; Chediak-Higashi Syndrome*/Chediak-Higashi Syndrome*/Chediak-Higashi Syndrome*/pathology; Lysosomes/Lysosomes/Lysosomes/*ultrastructure

  • Source: Traffic (Copenhagen, Denmark) [Traffic] 2012 Jan; Vol. 13 (1), pp. 108-19. Date of Electronic Publication: 2011 Nov 09.Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0854

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Academic Journal

Chediak-Higashi Syndrome: a rare disorder of lysosomes and lysosome related organelles.

  • Authors : Shiflett SL; Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.; Kaplan J

Subjects: Chediak-Higashi Syndrome/Chediak-Higashi Syndrome/Chediak-Higashi Syndrome/*genetics ; Eukaryotic Cells/Eukaryotic Cells/Eukaryotic Cells/*metabolism ; Lysosomes/Lysosomes/Lysosomes/*genetics

  • Source: Pigment cell research [Pigment Cell Res] 2002 Aug; Vol. 15 (4), pp. 251-7.Publisher: Munksgaard International Publishers Country of Publication: Denmark NLM ID: 8800247 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Roles and Mechanisms of the Protein Quality Control System in Alzheimer's Disease.

  • Authors : Liu Y; Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.; Ding R

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Proteins/Proteins/Proteins/*metabolism; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 29; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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