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Academic Journal

hsa_circ_0020093 suppresses ovarian cancer progression by modulating LRPPRC activity and miR-107/LATS2 signaling.

  • Authors : Sun Y; Department of Gynecology, Women's Hospital of Nanjing Medical University (Nanjing Women and Children's Healthcare Hospital), 123 Tianfei Xiang, Mochou Road, Nanjing, 210004, China.; School of Pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, UK.

Subjects: Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism ; RNA, Circular*/RNA, Circular*/RNA, Circular*/genetics

  • Source: Biology direct [Biol Direct] 2024 Aug 21; Vol. 19 (1), pp. 69. Date of Electronic Publication: 2024 Aug 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150

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Academic Journal

Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.

  • Authors : Qin C; Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, P. R. China.; Key Laboratory of Research in Pancreatic Tumor, Chinese Academy of Medical Sciences, Beijing, P.R. China.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Journal of extracellular vesicles [J Extracell Vesicles] 2024 Aug; Vol. 13 (8), pp. e12488.Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print Cited Medium: Internet ISSN: 2001-3078

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Academic Journal

The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/drug therapy ; Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/metabolism

  • Source: BMC cancer [BMC Cancer] 2024 May 14; Vol. 24 (1), pp. 587. Date of Electronic Publication: 2024 May 14.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway.

  • Authors : Zhang Y; Department of Gastroenterology and Hepatology, the First Affiliated Hospital, Sun Yat-sen University, No.58 Zhongshan 2nd Road, Guangzhou, 510630, China.; Department of Hepatobiliary surgery, the Third Affiliated Hospital, Sun Yat-sen University, No.600 Tian he Road, Guangzhou, 510630, China.

Subjects: Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/*drug effects ; Cyclin-Dependent Kinase 6/Cyclin-Dependent Kinase 6/Cyclin-Dependent Kinase 6/*drug effects ; Hippo Signaling Pathway/Hippo Signaling Pathway/Hippo Signaling Pathway/*drug effects

  • Source: Clinical and translational medicine [Clin Transl Med] 2021 Aug; Vol. 11 (8), pp. e503.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω.

  • Authors : Ma C; Clinical and Research Center of Infectious Disease, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, P.R. China.; Peng P

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2020 Jul; Vol. 22 (1), pp. 483-493. Date of Electronic Publication: 2020 Apr 21.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer.

  • Authors : Morgan EL; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, U.K, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, U.K, United Kingdom.

Subjects: Cell Transformation, Viral* ; Signal Transduction*; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2020 Jun 18; Vol. 16 (6), pp. e1008624. Date of Electronic Publication: 2020 Jun 18 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

m 6 A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC.

  • Authors : Jin D; Clinical Medical Laboratory, Binzhou Medical University Hospital, Binzhou, 256603, People's Republic of China.; Guo J

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; AlkB Homolog 5, RNA Demethylase/AlkB Homolog 5, RNA Demethylase/AlkB Homolog 5, RNA Demethylase/*metabolism ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*secondary

  • Source: Molecular cancer [Mol Cancer] 2020 Feb 27; Vol. 19 (1), pp. 40. Date of Electronic Publication: 2020 Feb 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

RASSF1A-Hippo pathway link in patients with urothelial carcinoma of bladder: plausible therapeutic target.

Subjects: Signal Transduction*; Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*metabolism ; Tumor Suppressor Proteins/Tumor Suppressor Proteins/Tumor Suppressor Proteins/*metabolism

  • Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2020 Jan; Vol. 464 (1-2), pp. 51-63. Date of Electronic Publication: 2019 Nov 21.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lats2-Underexpressing Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate LPS-Induced Acute Lung Injury in Mice.

  • Authors : Dong L; Department of Critical Care Medicine, Taizhou Central Hospital, Taizhou University Hospital, Taizhou, Zhejiang 318000, China.; Li L

Subjects: Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*chemically induced ; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*therapy ; Bone Marrow Cells/Bone Marrow Cells/Bone Marrow Cells/*cytology

  • Source: Mediators of inflammation [Mediators Inflamm] 2019 Oct 21; Vol. 2019, pp. 4851431. Date of Electronic Publication: 2019 Oct 21 (Print Publication: 2019).Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 9209001 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Activating Hippo Pathway via Rassf1 by Ursolic Acid Suppresses the Tumorigenesis of Gastric Cancer.

  • Authors : Kim SH; Department of Internal Medicine, Chonbuk National University Medical School, Jeonju 54907, Korea. .; Jin H

Subjects: Carcinogenesis/Carcinogenesis/Carcinogenesis/*drug effects ; Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*metabolism ; Signal Transduction/Signal Transduction/Signal Transduction/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Sep 23; Vol. 20 (19). Date of Electronic Publication: 2019 Sep 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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