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  • 1-10 ل  2,918 نتائج ل ""Ataxia""

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Subject : protein serine-threonine kinases
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Academic Journal

STK39-mediated amplification of γ-H2A.X promotes homologous recombination and contributes to PARP inhibitor resistance.

  • Authors : Xu Y; State Key Laboratory of Molecular Oncology and Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Panjiayuan Nanli No17, Chaoyang District, Beijing 100021, China.; Li C

Subjects: Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Dec 11; Vol. 52 (22), pp. 13881-13895.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A sterol-PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response.

  • Authors : Ovejero S; Institut de Génétique Humaine (IGH), Université de Montpellier-Centre National de la Recherche Scientifique, Montpellier Cedex 5, France.; Department of Biological Haematology, CHU Montpellier, Montpellier Cedex 5, France.

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/genetics

  • Source: The EMBO journal [EMBO J] 2023 Aug 01; Vol. 42 (15), pp. e112684. Date of Electronic Publication: 2023 Jun 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response.

  • Authors : Wang L; College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.; Zhan L

Subjects: Arabidopsis/Arabidopsis/Arabidopsis/*genetics ; Arabidopsis Proteins/Arabidopsis Proteins/Arabidopsis Proteins/*metabolism ; Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Feb 22; Vol. 49 (3), pp. 1411-1425.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase.

  • Authors : Kang Y; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.; Han YG

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Replication Protein A*/Replication Protein A*/Replication Protein A*/metabolism; Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Aug 25; Vol. 51 (15), pp. 7936-7950.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Cross‐talk between DNA damage response and the central carbon metabolic network underlies selective vulnerability of Purkinje neurons in ataxia‐telangiectasia

Subjects: Ataxia Telangiectasia; Purkinje Cells; Humans

  • Source: Journal of Neurochemistry. 166:654-677

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Academic Journal

Underexpression and abnormal localization of ATM products in ataxia telangiectasia patients bearing ATM missense mutations.

Subjects: Mutation, Missense*; Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*genetics ; Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*metabolism

  • Source: European journal of human genetics : EJHG [Eur J Hum Genet] 2012 Mar; Vol. 20 (3), pp. 305-12. Date of Electronic Publication: 2011 Nov 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9302235 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours.

  • Authors : Reiman A; School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK.; Srinivasan V

Subjects: Mutation*; Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*genetics ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

  • Source: British journal of cancer [Br J Cancer] 2011 Aug 09; Vol. 105 (4), pp. 586-91. Date of Electronic Publication: 2011 Jul 26.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited

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Academic Journal

Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians.

  • Authors : Piaceri I; Department of Neurological and Psychiatric Sciences, University of Florence and Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Largo Brambilla, 3, 50134 Florence, Italy.; Bagnoli S

Subjects: Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*genetics ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

  • Source: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2013 Apr; Vol. 34 (4), pp. 573-5. Date Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Immunodeficiency in ataxia telangiectasia is correlated strongly with the presence of two null mutations in the ataxia telangiectasia mutated gene.

  • Authors : Staples ER; Department of Immunology, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; McDermott EM

Subjects: Mutation, Missense*; Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*immunology ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*genetics

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2008 Aug; Vol. 153 (2), pp. 214-20. Date of Electronic Publication: 2008 May 26.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia.

  • Authors : Li J; Department of Cell Biology and Neuroscience, Nelson Biological Laboratories, Rutgers University, Piscataway, New Jersey, USA.; Chen J

Subjects: Ataxia Telangiectasia/Ataxia Telangiectasia/Ataxia Telangiectasia/*metabolism ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism

  • Source: Nature medicine [Nat Med] 2012 May; Vol. 18 (5), pp. 783-90.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 ل  2,918 نتائج ل ""Ataxia""