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Academic Journal

The Periplasmic Oxidoreductase DsbA Is Required for Virulence of the Phytopathogen Dickeya solani .

Authors : Przepiora T; Department of General and Medical Biochemistry, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdansk, Poland.; Figaj D

Subjects: Protein Disulfide-Isomerases* ; Virulence*; Dickeya/Dickeya/Dickeya/*enzymologyDickeya solani

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 09; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics.

Authors : Verderosa AD; Institute of Health and Biomedical Innovation and Centre for Immunology and Infection Control, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, 4059, Australia.; Dhouib R

Subjects: High-Throughput Screening Assays/High-Throughput Screening Assays/High-Throughput Screening Assays/*methods ; Protein Disulfide-Isomerases/Protein Disulfide-Isomerases/Protein Disulfide-Isomerases/*analysis ; Protein Disulfide-Isomerases/Protein Disulfide-Isomerases/Protein Disulfide-Isomerases/*antagonists & inhibitors

Source: Scientific reports [Sci Rep] 2021 Jan 15; Vol. 11 (1), pp. 1569. Date of Electronic Publication: 2021 Jan 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors.

Authors : Duncan LF; Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne 3086, Australia. .; Wang G

Subjects: Benzofurans/Benzofurans/Benzofurans/*pharmacology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Escherichia coli/Escherichia coli/Escherichia coli/*enzymology

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Oct 18; Vol. 24 (20). Date of Electronic Publication: 2019 Oct 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Soluble expression of IGF1 fused to DsbA in SHuffle™ T7 strain: optimization of expression and purification by Box-Behnken design.

Authors : Emamipour N; Molecular Parasitology Laboratory, Department of Parasitology, Pasteur Institute of Iran, Tehran, Iran.; Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.

Subjects: Escherichia coli K12/Escherichia coli K12/Escherichia coli K12/*genetics ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*genetics ; Industrial Microbiology/Industrial Microbiology/Industrial Microbiology/*methods

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2019 Apr; Vol. 103 (8), pp. 3393-3406. Date of Electronic Publication: 2019 Mar 14.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development.

Authors : Christensen S; Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland, Australia.; Griffith Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia.

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Chlamydia trachomatis/Chlamydia trachomatis/Chlamydia trachomatis/*metabolism ; Disulfides/Disulfides/Disulfides/*metabolism

Source: PloS one [PLoS One] 2019 Sep 19; Vol. 14 (9), pp. e0222595. Date of Electronic Publication: 2019 Sep 19 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Improving Fab' fragment retention in an autonucleolytic Escherichia coli strain by swapping periplasmic nuclease translocation signal from OmpA to DsbA.

Authors : Schofield DM; Department of Biochemical Engineering, University College London, Bernard Katz Building, London, WC1E 6BT, UK.; Sirka E

Subjects: Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/Bacterial Outer Membrane Proteins/*genetics ; Escherichia coli/Escherichia coli/Escherichia coli/*genetics ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*genetics

Source: Biotechnology letters [Biotechnol Lett] 2017 Dec; Vol. 39 (12), pp. 1865-1873. Date of Electronic Publication: 2017 Sep 05.Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8008051 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase.

Authors : Christensen S; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, St. Lucia, Queensland, Australia.; Grøftehauge MK

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Chlamydia trachomatis/Chlamydia trachomatis/Chlamydia trachomatis/*physiology

Source: PloS one [PLoS One] 2016 Dec 28; Vol. 11 (12), pp. e0168485. Date of Electronic Publication: 2016 Dec 28 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Expression and rapid purification of recombinant biologically active ovine growth hormone with DsbA targeting to Escherichia coli inner membrane.

Authors : Durrani FG; School of Biological Sciences, University of the Punjab, Lahore, Pakistan.; Gul R

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*metabolism ; Escherichia coli/Escherichia coli/Escherichia coli/*metabolism ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*genetics

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2015 Aug; Vol. 99 (16), pp. 6791-801. Date of Electronic Publication: 2015 Jun 28.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.

Authors : Duprez W; Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Bachu P

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Oxidoreductases/Oxidoreductases/Oxidoreductases/*metabolism ; Peptides/Peptides/Peptides/*pharmacology

Source: PloS one [PLoS One] 2015 Jul 30; Vol. 10 (7), pp. e0133805. Date of Electronic Publication: 2015 Jul 30 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Modulation of biofilm-formation in Salmonella enterica serovar Typhimurium by the periplasmic DsbA/DsbB oxidoreductase system requires the GGDEF-EAL domain protein STM3615.

Authors : Anwar N; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Biofilms/Biofilms/Biofilms/*growth & development ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

Source: PloS one [PLoS One] 2014 Aug 25; Vol. 9 (8), pp. e106095. Date of Electronic Publication: 2014 Aug 25 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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نتائج البحث

فلترة النتائج

The Periplasmic Oxidoreductase DsbA Is Required for Virulence of the Phytopathogen Dickeya solani .

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics.

The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors.

Soluble expression of IGF1 fused to DsbA in SHuffle™ T7 strain: optimization of expression and purification by Box-Behnken design.

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development.

Improving Fab' fragment retention in an autonucleolytic Escherichia coli strain by swapping periplasmic nuclease translocation signal from OmpA to DsbA.

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase.

Expression and rapid purification of recombinant biologically active ovine growth hormone with DsbA targeting to Escherichia coli inner membrane.

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.

Modulation of biofilm-formation in Salmonella enterica serovar Typhimurium by the periplasmic DsbA/DsbB oxidoreductase system requires the GGDEF-EAL domain protein STM3615.

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