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Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer

Subjects: Tafamidis; Protein Conformation, alpha-Helical; Diflunisal / chemistry

  • Source: International Journal of Molecular SciencesVolume 21Issue 19International Journal of Molecular Sciences, Vol 21, Iss 7166, p 7166 (2020)Digital.CSIC. Repositorio Institucional

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Key residues in TLR4-MD2 tetramer formation identified by free energy simulations

Subjects: 0301 basic medicine; Lipopolysaccharides; Models, Molecular

  • Source: PLoS Computational BiologyPLoS computational biology, vol 15, iss 10PLoS Computational Biology, Vol 15, Iss 10, p e1007228 (2019)

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